Gene therapy research switches off joint inflammation; switches on genetic process of joint repair
...rowski emphasized that "If joints are like a brick wall made from bricks of glucosamine, and then it makes sense that to rebuild a functional wall that you need the master bricklayer and not just the simple approach of getting more bricks." Elabor...Three-dimensional, miniature endoscope opens new diagnostic possibilities
...o image metastatic ovarian tumors on the abdominal wall of a mouse. The SEE probe was passed into the abdominal cavity through a fine-gauge needle. The resulting three-dimensional image showed several raised areas of tumor nodules, the presence of which was confirmed by histologic analysis of the tissue...Otherworldly bacteria discovered two miles down
...nature arises from interacting with the fracture's wall rock," commented Rumble. "It is possible that communities like this can sustain themselves indefinitely, given enough input from geological processes. Time will tell how many more we might find in Earth's crust, but it is especially exciting to ponde...Neural stem cells lend the brain a surprising capacity for self-repair
...and an unexpected role in maintaining the cellular wall that lines the ventricular region of the brain in ...ides. Without the normal complement of genes, that wall "disintegrated," he said, leaving holes in the brain. Surprisingly, they reported, the ventricular...UCSD researchers create roadmap to integrin activation
...tors ?changes that enable platelets to bind to the wall of blood vessels and to one another. "The road map of the activation pathway could lead to the development of new antithrombotic drugs or treatments for inflammatory diseases. In addition, the ability to engineer these activation pathways may cont...Ferns provide model for tiny motors powered by evaporation
...of water, into motion. When the cells in the outer wall of the sporangium were water logged, the sporangiu...res safely inside. But when the water in the outer wall evaporated, it caused the sporangium to unfurl and eject the spores into the environment. The rese...Distinguishing friend from foe in the battle against cancer
...ugs are, cancer cells with their backs against the wall have the tendency to fight back. A major goal of cancer research is to frustrate these acts of cellular desperation. In a forthcoming issue of Cancer Cell, investigators at the Salk Institute for Biological Studies uncover one means cancer cells use...Rescuing injured hearts by enhancing regeneration
...ts. They also had reduced thinning of the cardiac wall and the least amount of scarring. Rats receiving only the p38 MAP kinase inhibitor had increased proliferation of cardiomyocytes, but no longer had improved heart function at three months. Those receiving only FGF1 maintained their functional impr...Who gives stem cells their marching orders?
...embryos already need Nodal when they attach to the wall of the uterus, to expand their pool of stem cells, and to let individual cells know where they are with respect to their neighbors. However, to carry out these tasks, the Nodal protein must be cleaved by specific enzymes. The enzymes act as a sort of...New findings could lead to vaccine for severe malaria
...roteins that attach themselves to receptors in the wall of the blood vessels. This causes the red blood cells to accumulate in organ capillaries, and gives rise to life-threatening symptoms. Adults who have been infected several times can become partly immune as their defence system gradually starts to re...Tearing down the fungal cell wall
...gene drastically impacts the integrity of the cell wall of fungal spores produced in the reproductive phas...tial role in maintaining the structure of the cell wall of the conidia. Associate Professor Christopher Lawrence of the Virginia Bioinformatics Institute...New approach could lower antibiotic requirements by 50 times
... them to throw out antibiotics. A pore in the cell wall would obviously cancel the efflux effect,' Hagens explains. Pseudomonas bacteria cause pneumonia and are a common cause of hospital-acquired infections. Experiments in mice revealed that 75% of those infected with a lethal dose of Pseudomonas sur...Batten down the hatches against HIV
.... The phospholipids nestle securely onto the outer wall of the carbon nanotubes while the polyethylene glycol chains protrude into the surrounding solution. The required RNA molecules were fastened to the ends of these chains. Once inside the cell, the RNA could easily be split off by means of a sulfur–su...Napoleon's mysterious death unmasked, UT Southwestern researcher says
...nother part of his stomach that had penetrated the wall and reached the liver. The researchers ?obviously unable to observe the body ?compared the original descriptions of the lesions with modern images of 50 benign ulcers and 50 gastric cancers. They determined that no benign cancer could look like th...Einstein's tea leaves inspire new blood separation technique
... as red blood cells would be pulled to the outside wall of the chamber owing to centrifugal force. But because of a phenomenon called the "tea leaf paradox," the particles are instead pulled inward near the bottom of the chamber. Einstein proposed an explanation to this phenomenon in 1926 when he noticed ...Study to explore using magnets to correct 'sunken chest'
...ed to apply a force to gradually remodel the chest wall without piercing the skin," Harrison said. "Magnet...chniques is that they attempt to reshape the chest wall in one big operation," Harrison said. "A better idea is to apply a little force over a longer time, ...MU researcher placing eye implants in cats to help humans see
...two small cuts into the sclera, the outer wall of the eyeball. After removing the vitreous, which is the gelatinous fluid inside the back part of the eyeball, Narfstrom creates a small blister in the retina and a small opening, large enough for the microchip, which is just two millimeters in d...Scientists discover how body fights to control spread of cancer
...he cancer cells from attaching to the blood vessel wall which causes secondary tumours. We have discovere...e cancer cells then eventually penetrate the blood wall to form tumours at secondary sites. "The attachment of cancer cells to the blood vessel wall is on...Penn study on olfactory nerve cells shows why we smell better when we sniff
...is a patch of smell-sensitive tissue on the septal wall of the nasal cavity. The second, the main olfactory epithelium, is a smell-sensitive tissue inside the nasal cavity. Synchronized Breathing The septal organ is only about 1 percent the size of the main olfactory epithelium and isn't shared by...... blood vessels. During inflammation, the vascular wall presents surface selectins that adhere specificall... they could attract a large number of cells to the wall of their selectin-coated device, and that 38% of these captured cells were stem cells. King envisio...