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Tag: "vitro" at biology news

Contagious obesity? Identifying the human adenoviruses that may make us fat

...tial of multiple human adenoviruses in vivo and in vitro in animals," in the January issue of the American ...n adenovirus to cause human obesity by using an in vitro assay or even by animal testing, screening of the approximately 50 human adenoviruses might be accel...

Bioengineers create stable networks of blood vessels

...rug delivery in a model system that can be used in vitro and in vivo." The researchers used two important engineering enhancements to develop stable functional microcirculation. First, they created a "micro-scaffold" of a macroporous hydrogel polymer. The hydrogel is a three-dimensional, sponge-like mater...

New technique puts brain-imaging research on its head

...ormation they have found with their subjects to in vitro experiments or to animal models to learn even more about brain matter deformation. They have done experiments on humans with the head dropping forward, and plan to study different acceleration profiles, including rotations. "This method is a start...

Eisai announces Phase II data on E7389, a potential new therapy for the treatment of breast cancer

...dies to have highly potent anti-cancer activity in vitro and in vivo. Halichondrin B was originally isolated from a type of marine sponge. This study was designed to evaluate E7389 as a monotherapy in patients with refractory breast cancer. The primary endpoint of this trial was response rate, measured us...

Genetic testing still smart choice, despite uncertainties

Screening embryos for genetic diseases during in vitro fertilization offers couples the best chance for a healthy child, but a genetic glitch could potentially cause doctors to misdiagnose a small fraction of them, University of Florida researchers say. Citing concerns about the accuracy of preimplanta...

Natural compound from 'pond scum' shows potential activity against Alzheimer's

...her neurodegenerative diseases, according to an in vitro study by researchers in Switzerland. It is believed to be the first time that a potent agent against Alzheimer's has been isolated from cyanobacteria, commonly known as 'pond scum.' The study was published in the Dec. 26 issue of the Journal of Natu...

Old drug shows new promise for Huntington's Disease

...alifornia, San Francisco (UCSF). Based on the in vitro results, Massa decided to test the drug in vivo, o...ly convincing," Massa concluded. "Together, the in vitro and in vivo results suggest that Clioquinol has an effect of decreasing the symptoms of Huntington's...

Most embryos produced during IVF do not result in live births

...d that 85 percent of embryos transferred during in vitro fertilization fail to become live births, highlighting the need for improving diagnostic techniques to identify viable embryos. Published in the August issue of Fertility and Sterility, the study reviewed seven years of U.S. statistics from all the ...

Optimizing cell therapy against tumors is a balancing ACT

...hat a pragmatic strategy for ACT is to keep the in vitro T cell expansion phase as short as possible to kee.... TITLE: Acquisition of full effector function in vitro paradoxically impairs the in vivo anti-tumor efficacy of adoptively transferred CD8+ T cells TITLE:...

Israeli scientists successfully transplant frozen-thawed ovaries in sheep

... The first aim of the Israeli team was to test in vitro whether whole ovaries from sheep, together with the blood vessels, could survive the freeze-thaw process using a technique they have developed that allows precise control over the propagation of ice crystals during the freezing process, thus reducing...

Visceral Leishmaniasis: Successful Vaccine Trial In Dogs

... and macromolecules (CDM/LP) for the continuous in vitro cultivation of infective promastigote forms. Am. J...vets : Lemesre J.L. (1993). "Procédé de culture in vitro de différents stades parasitaires obtenus et applications biologiques". Brevet français, FR n° 93 05...

Engineered molecule amplifies body's immune response

...fits of interferon in the body." Their initial in vitro results were promising, and the engineered Stat1 molecule exhibited an increased responsiveness to interferon. Following up on these discoveries, Dr. Holtzman and his colleagues are currently performing gene transfer experiments, using both recombina...

Gene Bridges And Covalys To Develop Restriction-Enzyme-Free SNAP-tag Gene Fusion Kits

...g of SNAP-tag fusion proteins in live cells and in vitro with fluorescent or affinity probes. Kits to be introduced later this year by Covalys will allow for immobilization without prior purification, and purification of SNAP-tag fusion proteins. "We are particularly happy about this collaboration," said ...

Endocannabinoids ?the brain's cannabis ?demonstrate novel modes of action to stress

...ory and inhibitory synaptic transmission In an in vitro study, a multi-center Japanese team led by Atsushi Soya focused on the supraoptic nucleus (SON) where vasopressin and oxytocin are synthesized. They found that a synthesized cannbinoid (CP55,940) inhibited both excitatory and inhibitory synaptic tran...

New Discovery May Help Doctors Treat Infertility

...une issue of Endocrinology, used a test tube or in vitro approach, to elucidate the role that estrogen rece...n of the two different methods, the in vivo and in vitro studies, complement each other nicely and provide more precise answers to the role that the estrogen...

Climate model links higher temperatures to prehistoric extinction

...ent precursor cells in the bone marrow. In the in vitro portion of the study, researchers used mouse bone marrow cells containing the stem cells that give rise to mast cells. They cultured these precursor cells in conditions that allow mast cells to develop, and then added IFNγ to some of these cultu...

VCU study shows hormone-like molecule kills cells that cause inflammation in allergic disease

...ent precursor cells in the bone marrow. In the in vitro portion of the study, researchers used mouse bone marrow cells containing the stem cells that give rise to mast cells. They cultured these precursor cells in conditions that allow mast cells to develop, and then added IFNγ to some of these cultu...

Gifts from the sea

...logical disorders, vision, immunology, and even in vitro fertilization. Here are some of the locally available organisms MBL researchers study and why: Long-finned, or Woods Hole, squid (Loligo pealeii): This squid's large nerve cell fiber, called a giant axon, has helped neuroscientists understand basic...

Anthrax inhibitors identified by Burnham team

...ly potent and selective against LF in vitro. In in vitro assays, the compounds did not affect prototype human metalloproteinase enzymes that are structurally similar to LF. This is very important as selectivity is a fundamental prerequisite for a drug to be safe for use in humans. Three lead compounds whe...

Invitrogen Launches i-Path -- A Unique Systems Biology Platform at BIO 2005

...n. Mr Heindryckx said: "Eighteen out of the 25 in vitro matured MII oocytes survived this nuclear transfer...g the development of cloned human embryos using in vitro matured oocytes and non-autologous transfer via a conventional method of nuclear transfer. "Our fin...

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