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Tag: "vitro" at biology news

MIT bioengineer advances survival, promise of adult stem cells

...stem cells following a personal experience with in vitro fertilization almost 10 years ago. "Like some other scientists I know, my personal views about creating human ES cell lines changed when confronted with the reality of doing so from my own embryos. After this experience, I was not comfortable co...

Cells selectively absorb short nanotubes

...in an open question. "Published data citing in vitro (outside the body) toxicity are particularly inconsistent and widely disputed," writes biomaterials scientist Matthew Becker and his NIST colleagues. Public concerns surrounding the environmental, health and safety impacts of SWCNTs could derail effo...

Growth factor stimulates rapid extension of key motor neurons in brain

...wth factor 1 (IGF-1) dramatically increases the in vitro growth of corticospinal motor neuron (CSMN) axons ...axons, which confirmed the applicability of the in vitro experiments to living mammals. "The role of IGF-1 as a potent and specific enhancer of CSMN axon...

Math model predicts cancer behavior

...treatment, he said. Next up for the group are in vitro and in vivo experiments designed to test, validate and refine the mathematical model. ...

Discovery in the evolution of the immune system absorbing cells

...able of strong phagocytosis both in in vivo and in vitro experiments. The work has been published in Nature Immunology, the most prestigious journal worldwide in the field of immunology. According to Dr Sunyer, "this is important so that we can understand not only how the immune systems of fish and amphi...

Antibody extends life of mice with breast cancer

...metastasizing." The antibody was tested using in vitro models of tumor cell growth, in assays to determine its ability to damage or kill cells (cytotoxicity), in various models of cancer metastasis, and, finally, in mice with metastatic breast cancer. "In addition to providing a survival advantage," ...

SARS: No evidence that any of the treatments worked

...eria. They found 54 SARS treatment studies, 15 in- vitro studies, and three acute respiratory distress syndrome studies. Some of the in-vitro studies with the antiviral drugs found that a particular drug reduced the reproduction rate of the viruses, but most of the studies of these drugs in patients were i...

A natural chemical found in strawberries boosts memory in healthy mice

...rvous system and also shown to enhance both LTP in vitro and long-term memory in vivo." "The good news is that fisetin is readily available in strawberries but the bad news is that because of its natural product status there may be little financial interest in getting it into human clinical trials for di...

Study offers innovative profile of enzyme that aids tumor growth

...ly, the activities of enzymes have been studied in vitro using purified protein preparations. The outcome o...of the most time-consuming steps that accompany in vitro enzyme analysis while generating data more directly related to their naturally occurring activities....

Test reveals effectiveness of potential Huntington's disease drugs

...t memantine holds the most promise based on its in vitro efficacy," Dr. Bezprozvanny said. "Whole animal studies of memantine in an HD mouse model will be required to validate these findings." ...

Researchers report technique for freezing and preserving genetically enhanced pig embryos

...d preserving swine embryos that were created by in vitro techniques and that carried modified genetic mater...reserve swine embryos that had been produced by in vitro methods. Dr. Prather's team overcame the obstacles to freezing swine embryos by first removing lipi...

Origen publishes in Nature a robust and versatile method for creating transgenic chickens

...itions, Origen scientists could induce the PGCs in vitro to differentiate into embryonic germ cells that contribute to somatic tissue. "As well as the practical applications of this work, the ability to engineer PGCs and influence them to commit in cell culture to either the germline or the somatic lineag...

New technology addresses female fertility preservation

...eady led to the live birth of healthy mice from in vitro grown follicles. The results are published online...each follicle has one egg) from mice were grown in vitro until fully matured by providing the follicles and eggs with the necessary hormones for development ...

Nanotechnology being used to improve biocompatibility of human prosthetics and implants

...echnological University, the nanostructures and in vitro osteoblast behavior of individual CP splats were characterized. The splats were deposited using both plasma spraying and high velocity oxy-fuel (HVOF) onto polished Ti-6Al-4V substrates. The results showed that the nanostructured HA splats are capa...

Sperm created in the laboratory from embryonic stem cells produce viable progeny

...dult mice. "Our approach provides an accessible in vitro model system for studies of mammalian gametogenesis, as well as for developing new strategies for generation of transgenic mice and may one day facilitate nuclear transfer technology and infertility treatment," offers Dr. Nayernia. ...

UCSD researchers develop 'smart petri dish'

...cant advantage compared to other techniques for in vitro monitoring of cell morphology," that is, for monitoring cells in the laboratory, outside of humans or animals. ...

Researchers unveil strategy for creating actively-programmed anti-cancer molecules

...utic application. The compound could be created in vitro and delivered as a conventional single therapy. Alternately, the small molecule and antibody could be injected separately, with the new complex formed in vivo. The authors note that even though the administration of two separate compounds might compl...

Unique dual target specificity of kinase inhibitor key for success against cancer

... a broad range of lethal malignant glioma cells in vitro and in vivo. The findings, published in the May issue of Cancer Cell, shed light on which PI3 kinase family members are most likely to play a role in cancer progression. This study reinforces the concept that successful small molecule kinase inhibito...

Think fast! Rice undergrad unlocks nerve speed secret

...rgely by undergraduate Johanna Schaub, involved in vitro experiments on a synthetic and highly controlled complex of membranes and proteins. Via these experiments, Schaub was able to show that SNARE-driven membrane fusion ?the act that opens the door for neurotransmitter to leave the neuronal cell ?was inh...

Case Western Reserve University researchers find protein associated with brain cell death

...tion between the plaque and immune cells. In in vitro studies of brain tissue from mice, the researchers found that the microglia had the appropriate immune response that the plaque was harmful, but then the protein Vav was found to be a component in oxidative damage since elimination of the protein res...

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