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Tag: "vital" at biology news

Man and mouse share genome structures

...ow that the human genome has been sequenced, it is vital to learn how the genome is translated to make living cells and organisms, and how we can use that information to improve human health," said Bernstein, who is an instructor of pathology at Brigham & Women's Hospital and Harvard Medical School. "E...

Elusive HIV shape change revealed; Key clue to how virus infects cells

...p120's structure before the shape change, yielding vital before-and-after information on how the molecule rearranges itself when it encounters the CD4 receptor. "Knowing how gp120 changes shape is a new route to inhibiting HIV ?by using compounds that inhibit the shape change," says Harrison. He notes tha...

Iron Deficiency Sparks Dramatic Changes In Gene Expression

...r genes affected by ironstarvation are known to be vital in generating energy, copying thecell's genetic code and protecting the cell from free radicals andaging, said Thiele."We discovered that iron deprivation actually reprograms the metabolismof the entire cell," said Thiele. "Literally hundreds of prot...

Enzyme shown to help protect genomic stability

...ve one reason for this broad gene silencing is the vital need for genomic stability, for protection against...te has shown that an enzyme known as Ubp10 plays a vital role in protecting the telomeric regions of the genome from potential destabilizing molecular events...

Poplar trees redirect resources in response to simulated attack

...evated carbon dioxide, soil toxins, and drought on vital plant processes." Ferrieri says scientists trying...only just beginning to realize that isoprene has a vital role as an antioxidant in helping plants tolerate many different stresses, for example from insects ...

Protein Packages Found To Activate Genes; May Be What Regulates Development And Disease

...ise," Bernstein admits. HOX genes, as noted, play vital roles in embryo development. Understanding how the...nto a complex living organism. HOX genes are also vital for understanding the way that people get certain cancers. "Many of the proteins that regulate these...

Vital step in cellular migration described by UCSD medical researchers

A vital molecular step in cell migration, the movement of cells within the body during growth, tissue repair and the body's immune response to invading pathogens, has been demonstrated by researchers in the University of California, San Diego (UCSD) School o...

Critical role in programmed cell death identified

...g new avenues for studying and targeting a process vital to development and implicated in cancer and autoimmune diseases. The work, reported in the February 17 issue of Nature, demonstrates the role of mitochondria, the cellular power plant, in prompting worm cells to self destruct. These results unify ce...

Gene Therapy For Parkinson's Disease Moves Forward In Animals

... caused by the death of brain cells that produce a vital chemical known as dopamine, which carries messages that tell the body how and when to move. In tests with 31 monkeys, including a control group, scientists inserted copies of a gene to produce GDNF into a region in the front part of the brain called ...

The Shapes Of Life: NIGMS Project Yields More Than 1,000 Protein Structures

...ide important information about these molecules so vital to life.?/p> The nine pilot centers participating in the first phase of the PSI are: * The Berkeley Structural Genomics Center, http://www.strgen.org/ * The Center for Eukaryotic Structural Genomics, http://www.uwstructuralgenomics.org/ * The ...

Tiny scaffolding allows stem cells to become working fat cells

...sity, a person's population of fat cells has other vital roles. Fat cells extract lipids, or fatty acids, from the bloodstream. They also become a huge reservoir for glucose as well, and play a role in insulins ability to effectively convert glucose into energy. "If we could learn how to control fat form...

New RNA polymerase discovered in plants

...es and retrotransposons is lost. Methylation is a vital process involving a chemical modification in cytosine, one of the four chemical subunits of DNA. Without proper DNA methylation, higher organisms from plants to humans have a host of developmental problems, from dwarfing in plants to tumor developmen...

Gene therapy for Parkinson's disease moves forward in animals

... caused by the death of brain cells that produce a vital chemical known as dopamine, which carries messages that tell the body how and when to move. In tests with 31 monkeys, including a control group, scientists inserted copies of a gene to produce GDNF into a region in the front part of the brain called ...

VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain

...r called Bdnf. Bdnf is found in the brain and is a vital part of nervous system development. "We found that the interaction between the Bdnf gene and several other genes that interact with Bdnf were all regulated in one region of the brain that is known to play a role in drug addiction," Miles said. "Thes...

Fleshing out the genome

...ng to their likelihood to encode proteins "will be vital for any further experimentation and, eventually, for predicting biological function," said Eugene Kolker, president and director of BIATECH, an affiliate scientist at PNNL and lead author of a study in the Feb. 8 Proceedings of the National Academy o...

NIH Calls on Scientists to Speed Public Release of Research Publications

...dies to ensure the permanent preservation of these vital research findings; 2. securing a searchable compendium of these research publications that NIH and its awardees can use to manage more efficiently and to understand better their research portfolios, monitor scientific productivity, and, ultimatel...

Light therapy may combat fungal infections, new evidence suggests

...tal signals such as light in fungal development is vital to increase the benefits and decrease the costs that fungi present." The researchers first tested the importance of genes with known roles in light sensitivity of another, distantly related fungus. Yeast strains lacking one of those genes, known as ...

Affymetrix Licenses Microfluidics Technology From Caliper Life Sciences

...Caliper's microfluidics technologies -- into these vital areas of human health is important to our corporate ideals and to our future as a key technology provider to the industry." The scope of the license agreement includes nucleic acids processing and handling associated with GeneChip arrays, but exclud...

Chemicals in tattoo inks need closer scrutiny

...ng popularity of tattoos among young people, it is vital that we develop a better understanding of this form of self expression." The new research ?a joint effort between Finley-Jones and Leslie Wagner as part of an undergraduate research project directed by Jani Ingram, a professor of chemistry at NAU ?h...

Solutions that reduce death of marine life reeled in by International Smart Gear Competition

... in a developing country. "While it's obvious how vital the ocean's been to me, we're all dependent on an ocean full of life and, in turn, it's dependent on our actions," said grand prize winner Steve Beverly, fisheries development officer for the Secretariat of the Pacific Community. "It's just common se...

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