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Tag: "visualize" at biology news

Simulations unravel outer membrane transport mechanism

...programs, NAMD and VMD, respectively, simulate and visualize complex molecular interactions. By entering detailed data about the position and characteristics of every atom in the system, the researchers ran simulations of various scenarios to test which hypotheses were most feasible. Their work relied on detai...

New Brandeis research sheds light on memory by erasing it

...ibitor is applied. This provides a way to directly visualize the forgetting process and complements previous work done in Lisman's laboratory showing that when LTP is induced (as during learning), CaMKII moves into the synapse. ...

Bones in motion: Brown scientists to create new 3-D X-ray system

... students are already at work on pilot projects to visualize pigs walking, birds flying and frogs jumping, using seed funds from Brown's Office of the Vice President for Research and the National Science Foundation. Software will be rolled out in phases, Brainerd said, with a complete system available by 2010....

Imaging pinpoints brain regions that 'see the future'

...pre-testing showed he was easy for participants to visualize in a variety of situations. Comparing images of brain activity in response to the "self-remember" and "self-future" event cues, researchers found a surprisingly complete overlap among regions of the brain used for remembering the past and those us...

Scientists learn the origin of rogue B cells

...Most of what scientists do is to create systems to visualize complex phenomena, then to allow nature to give you the answers to your questions," says Casellas. Their new findings raise the question of how this knowledge might eventually help people with autoimmune disease. That question, says Casellas, is o...

Imaging techniques permit scientists to follow a day -- or four -- in the life of a cell

...nd cellular biologists, and advanced techniques to visualize cells in action are of great importance. The current issue of Cold Spring Harbor Protocols ( www.cshprotocols.org ) addresses these concerns with two freely accessible protocols: one for inserting 'reporter' proteins into cells to monitor what's go...

Proteins important in Alzheimer's, Parkinson's disease travel in the slow lane

...alized." Roy devised a system to simultaneously visualize the transport of two labeled slow-component-b proteins in living cultured mouse axons. This clarified unique aspects of slow-protein transport. He found that the "slow" proteins actually showed rapid bursts of movement followed by pauses. This interm...

HIV protein enlisted to help kill cancer cells

...d to cancer cells. "Dr. Mach designed tracers to visualize cancer in PET (positron emission tomography) scans," Hawkins says. "By binding our molecules to the tracers, we can deliver them to cancer cells. We've seen phenomenal results in the lab." Next Hawkins plans to combine pro-apoptotic proteins such a...

UCLA/Toronto researchers unlock key to memory storage in brain

...d with patterned walls and a unique smell. To visualize which brain cells stored the mouse's memories about the cage, the scientists tracked a genetic marker that reveals recent neuron activity. When the team examined the animals' amygdalas after the experiment, they found substantial amounts of CREB and...

Light-based probe 'sees' early cancers in first tests on human tissue

...anced version of an endoscope, instruments used to visualize internal organs, provided the clinical information required for diagnosis. The work was supported by the National Cancer Institute and the National Science Foundation. "Our initial study is very promising," Wax said of the findings. "We looked ...

Gene key to taste bud development identified

... up," Pevny explained. "This allows us to directly visualize those areas where SOX2 is active. It is a very powerful tool." In their work, Hogan and her colleagues use this fluorescence marker as a tool for tracking the activity of SOX2 in the esophagus, among other sites. As they worked with the mice, they ...

Nanoscale microscope sheds first light on gene repair

...represents a significant advance in our ability to visualize and quantify nuclear proteins in 3D." Bewersdorf, Bennett and Knight examined a protein called H2AX, a kind of histone. Histones are structural proteins that act as spools around which DNA is wound, and they can also play roles in gene regulation ...

Researchers image molecular motor structural changes

...sary to move along the microtubules. "In order to visualize the actual structure of the motor molecule bound to a microtubule, we combined the images generated by high-resolution electron microscopy," said study investigator Sharyn Endow, Ph.D., a Duke cell biologist. "We were able to see for the first time t...

Newly discovered behavior in cancer cells signals dangerous metastasis

...curred in the tumors. The researchers were able to visualize specific portions of DNA, called exons, to see if ... cells but is active in epithelial cells. "We can visualize the genes as they are dynamically changing," he said. "We can define the cell types by observing the...

Innovative movies show real-time immune-cell activity within tumors

...nts," Weninger says. "First, it is now possible to visualize the behavior of the individual cellular components of the tumor microenvironment in real-time. Second, we have demonstrated that T cells physically interact with tumor cells, which had not been shown before. Finally, it's the presence of antigen that...

Molecular anatomy of influenza virus detailed

...er them in the act of infection. "Being able to visualize influenza virus particles should boost our efforts to prepare for a possible pandemic flu attack," says NIAMS Director Stephen I. Katz, M.D., Ph.D. "This work will allow us to 'know our enemy' much better." One of the difficulties that has hampered...

Results with newer bladeless LASIK equivalent to standard microkeratome LASIK

... its computer-controlled precision, the ability to visualize the flap being created, and to stop the procedure whenever necessary. That said, however, the risk of complications with a traditional, microkeratome blade is very small: some vision loss from surgery with a microkeratome blade occurs in well under 1...

The molecular post office inside the cell

...Molecular Genetics in Berlin have now been able to visualize the structure of a "molecular machine" involved in protein sorting using cryo-electron microscopy and single particle analysis. This "machine" is made up of a single active ribosome, plus a special signal recognition protein and a matching receptor...

Scientists solve sour taste proteins

... which stimuli caused the ion channels to open. To visualize the presence of calcium ions in the cell, the scientists loaded the cells with two calcium-sensitive fluorescent dyes -- one that glowed green when the calcium concentration was high, the other that glowed red when the concentration was low. When th...

New GI technologies improve internal organ visualization

...y the possible benefit of endoscopic ultrasound to visualize the heart and help guide interventions. This s...ound (EUS) is frequently performed with a scope to visualize and detect abnormalities in the GI tract. Using EUS to guide them, researchers punctured the myoca...

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