Potent possibilities for parasite attack
... and L. braziliensis, which cause life-threatening visceral and disfiguring mucocutaneous leishmaniasis, respe...need new research, as WHO/TDR notes: "Treatment of visceral leishmanisis by first-line drugs is long (4 weeks), given systemically, and expensive (US$120–150)"....Keeping the immune system from starting a 'food fight'
...MP2, develop acute inflammation in deep pockets of visceral fat. The animals also showed symptoms of metabolic... they reported. Similarly, they showed that the visceral fat surrounding the internal organs of STAMP2-deficient mice became inflamed, and the animals develo...Just like us, social stress prompts hamsters to overeat, gain weight
...re weight gained significantly more fat, including visceral fat These results occurred when the intruder ham...se, like humans, they add fat to their abdomens -- visceral fat. Visceral fat is particularly unhealthy because it affects the internal organs and is associated...Forsyth scientists gain greater understanding of how embryos differentiate left from right
... gene expression and the position of the heart and visceral organs," Levin said. "We have now identified and explored an additional component of this novel mechanism ?a protein pump that generates voltage and pH gradients. For the first time, we have a glimpse of how three different vertebrates utilize such i...Potential vaccine developed for deadly leishmaniasis disease
...entally new "candidate," or potential, vaccine for visceral leishmaniasis, a parasitic disease that kills abou... Spread by the bite of infected female sand flies, visceral leishmaniasis infects about 500,000 people annually, with the majority of cases occurring in India, ...Contagious obesity? Identifying the human adenoviruses that may make us fat
... ending the experiment and measuring the chickens' visceral fat, total body fat, serum lipids, and viral antib...ies. Chickens inoculated with Ad-37 had much more visceral fat and body fat compared with the chickens infected with Ad-2, Ad-31 or the control group, even tho...Cells from amniotic fluid used to tissue-engineer a new trachea
...in the diaphragm that separates the lungs from the visceral organs. If the hole is large enough, the stomach and other visceral organs can end up in the chest cavity, crowding the lungs and stunting their growth. Using mesenchym...A New Era Of Hope For Neglected Diseases
...rectal artesunate for malaria, and paromomycin for visceral leishmaniasis). These PPP-driven projects should result in six or seven new drug registrations in the next five years. Research by Dr Moran and her colleagues has shown that PPPs have been a critical driver of this considerable increase in activity,...Visceral Leishmaniasis: Successful Vaccine Trial In Dogs
...m 1 to 42 % depending on the area, are affected by visceral leishmaniasis. These animals are thus a reservoir ... animal thus acquires long-term protection against visceral leishmaniasis. Although this vaccine’s effectiveness has been shown only on a limited number of ani...Insulin pulses keep the liver lean
...the hormone, leading to greater fat production and visceral weight gain. Resulting hikes in blood sugar and fat can also spell diabetes and heart disease, Najjar added. "When we eat, the pancreas produces insulin, which stimulates the absorption of sugar and fat by the liver," Najjar said. "But in today's We...OneWorld Health drug receives 'Orphan' designation from U.S. and European regulatory agencies
...edicinal Products (EMEA), for paromomycin to treat visceral leishmaniasis (VL). VL, also known as kala azar (...tes. The largest-ever Phase III clinical trial for visceral leishmaniasis was completed in November 2004 by OneWorld Health in collaboration with the Special Pr...