Hantavirus found in African wood mouse
... Netherlands. "This novel hantavirus is related to viruses that cause severe disease in humans in Central and...ncluding, fever, kidney failure, and bleeding. The viruses are carried by a number of rodents, including the brown rat, the striped field mouse, and the yellow...Flu not the only germ threat this time of year
... and maybe in your nose and lungs too. Some of the viruses are also wafting through the air you breathe, look...ren't really the flu at all, but other respiratory viruses like RSV. RSV is responsible for a lot of the illness blamed on flu," said Falsey, whose work is fun...Single microRNA causes cancer in transgenic mouse
...ct the presence of foreign invaders like bacteria, viruses or parasites. Lab tests revealed that the B cells in enlarged spleens had stopped evolving in the pre-B phase, right at the point where a B cell normally begins to create structures necessary for antibody development. "We believe that miR 155 ini...Gene-specific Ebola therapies protect non-human primates from lethal disease
...use they are designed to enter cells and eliminate viruses by preventing their replication. The drugs, which act by blocking critical viral genetic sequences, may be more potent than anti-virals such as protease inhibitors, which seek to inhibit a protein needed for viral replication. Ebola virus causes he...Protein finding could lead to treatment for inflammatory diseases
...regarding MC160 provide yet another example of how viruses inhibit NF-kB activation," Shisler said. "So we ar...anism, that of inhibiting NF-kB activity, that all viruses are trying to utilize to survive in the host. What is interesting is that MC160 appears to be doing ...Research details how a virus hijacks cell signals to cause infection
...to infect human cells. Broadening knowledge of how viruses cause infection, a new study describes elaborate m...es or growth factors. We showed in this study that viruses can co-opt kinase signaling processes to advance an infection." In describing how the coxsackieviru...New mechanism for essential genome-wide gene silencing identified
...lencing is also thought to protect the genome from viruses and other potentially damaging entities, thus preserving genetic integrity. In a new study, researchers at The Wistar Institute and colleagues have identified an important new global mechanism for this essential gene silencing, or gene repression. A...Biologists visualize protein interaction that may initiate viral infection
...but in order to do that we first have to learn how viruses work and how they initiate infection." The findin... adhesion molecule, a family of cell proteins that viruses bind to, and the number 3 defines a specific protein. "The binding occurs on dendritic cells, which...Viral 'fitness' explains different resistance patterns to aids drugs
...lity of the virus to replicate. These PI-resistant viruses only emerge, therefore, when challenged with high concentrations of drug. Overall, study findings showed that NNRTI resistance was found less often than PI resistance among patients who took the pills as directed. "We believe that when new drug ...Computer simulation hints at new HIV drug target
...retroviral therapy in the United States harbor HIV viruses that are resistant to at least one of the available drugs. In fact, people with an infection typically have a diverse array of HIV mutants, some of which are resistant to antiviral drugs. Drug-resistant strains of HIV are being found more often in re...Major WHO study concludes calcium supplements can reduce complications during pregnancy
...retroviral therapy in the United States harbor HIV viruses that are resistant to at least one of the available drugs. In fact, people with an infection typically have a diverse array of HIV mutants, some of which are resistant to antiviral drugs. Drug-resistant strains of HIV are being found more often in re...A clue from macaques yields evidence for impaired retroviral defense genes in humans
...version appears to respond to evolutionarily older viruses that are related to now-extinct viruses that are resident in the human genome. Previous studies had suggested that relatively few evolutio...Novel virus entry mechanism could lead to new drugs against poxviruses
...embrane must be removed. Previously, all enveloped viruses were thought to shed their lipid membrane by fusio...cal process. It increases our understanding of how viruses can manipulate biological membranes and will help the development of new drugs against poxviruses, s...Scientists force viruses to evolve as better delivery vehicles for gene therapy
...of California, Berkeley, researcher has shown that viruses - in this case, a benign one - can be forced to ev...hat the technique could be used to help pathogenic viruses evade the human immune system, potentially making them more virulent, he said that other and easier ...The diversity of marine life in the Gulf of Maine region is much greater than previously thought
...much of the sea floor and microscopic bacteria and viruses that live throughout the ecosystem. While most are invisible to the human eye, they are collectively major players in the web of ocean life." The Census of Marine Life is a global network of researchers in more than 70 nations engaged in a ten-year...Jefferson researchers building a better rabies vaccine
... will arouse the immune system's defenses. Because viruses such as rabies have high mutation rates, researchers typically "passage" the virus through mice. That is, they inject it into the animals, recover it, and then put into a second mouse. This is repeated at least five times. Five generations, Dr. Dietz...UCLA paper examines how one disease may prevent another
...d that new evidence can be found for using certain viruses to treat diseases such as HIV, which do not respond to other medications. "There have been several studies indicating that HIV patients co-infected with a virus related to Hepatitis C, called GB virus C, have less severe HIV disease and improved sur...Scientists identify molecular structure of key viral protein
.... The parainfluenza virus 5 is part of a family of viruses (paramyxoviruses) that causes everything from pneu... in particular, proteins associated with enveloped viruses such as HIV, influenza virus and the paramyxoviruses -- have two dramatically different shapes, one ...Researchers use mass spectrometry to detect norovirus particles
...illance tool for the detection of pathogenic human viruses in complex environmental samples such as human and animal waste." Typically, bacteria and viruses are identified by cultivation on selective media and cell lines. However, this process does not work......It now seems the answers might all be found in the viruses that infect them. Dr Alexei Drummond, from The U...l research team analysing the genetic sequences of viruses in animals. This pioneering technique has so far proved to be more effective than the traditional ...