UW scientists report a new method to speed bird flu vaccine production
...technique to more efficiently produce the disarmed viruses that are the seed stock for making flu vaccine in ...man immune system to recognize and defeat the wild viruses that spread among humans in an epidemic or pandemic. In their report, a team led by UW-Madison viro...Stolen gene allows insect virus to enter cells
...sts have long thought of baculoviruses, a group of viruses that can liquefy their insect hosts in a matter of...neeze in mammals, as potential pesticides. But the viruses would require tweaking to be effective since they kill insects more slowly than chemical insecticide...Metal-containing compounds show promise as HIV weapon
...to fight HIV/AIDS, but they have side effects, and viruses can develop resistance to them. "This molecule has all the characteristics of a good starting point for a new class of compounds," said Dr. Zbyszek Otwinowski, associate professor of biochemistry at UT Southwestern and an author on the study, which ...Drug resistant avian influenza viruses more common in Southeast Asia than North America
...f a key protein in different subtypes of avian flu viruses shows that resistance to the antiviral drug amanta...ne is spreading more rapidly among avian influenza viruses of H5N1 subtype in Southeast Asia than in North America, according to the study done by investigator...UF scientist finds unexpected link between cat and human AIDS viruses
Emerging relationships between the two viruses could one day lead to a vaccine for human A Unive...cher has discovered an unexpected link between the viruses that cause feline and human AIDS: Cats vaccinated with an experimental strain of the human AIDS viru...New study shows measles immunization may prevent fatal brain infection
...ildren under the age of five, or because wild-type viruses of the genotype identified are more likely to cause SSPE. The measles vaccine is known to be highly effective. Two doses provide immunity to 99 percent of those vaccinated. Since the risk of SSPE was much higher than originally estimated, and since...Preventing a pandemic: Study suggests strategies for containing a flu outbreak
...of 2.4 is relatively contagious, though some other viruses such as measles are substantially higher. In all cases, early intervention would be essential. The authors note in their study that the current World Health Organization stockpile of antivirals for avian flu could probably be sufficient to help cont...Prions rapidly 'remodel' good protein into bad, Brown study shows
...ike DNA and RNA ?the genetic material in bacteria, viruses and other infectious agents ?the research helps explain the puzzling process of how prions multiply and spread infection. Satpute-Krishnan said the speed of protein conversion was surprising. "The prions were taking all the existing protein and refo...Gene therapy reverses genetic mutation responsible for heart failure in muscular dystrophy
...ociated virus, or AAV, a class of relatively small viruses that do not cause any known disease. In earlier studies, Dr. Xiao's team found that direct intramuscular injection of AAV was effective in transferring a gene into muscle cells in a fairly wide area around the injection site. However, for gene therap......t require water and rapidly kill most bacteria and viruses on the skin. They are a convenient alternative for busy parents who are unable to get to a sink while caring for sick children. According to the U.S. Census Bureau, more than 7.5 million children under age 5 are enrolled in day care, placing them a...Agricultural workers at increased risk for infection with animal flu viruses
...ve a markedly increased risk of infection with flu viruses that infect pigs, according to a study funded in p...igs can be infected by swine viruses, bird (avian) viruses as well as human flu viruses--thereby acting as a virtual virus "mixing bowl," especially on farms w...New factor implicated in allergy and asthma attacks
...ne response the body uses to defend itself against viruses and bacteria. Now, though, researchers at the University of Texas Medical Branch at Galveston have discovered strong evidence that an additional factor is necessary to cause the severe respiratory inflammation involved in an allergy or asthma attack...HIV inserts into human genome using a DNA-associated protein
...cribes the first clear target for modulating where viruses insert into the human genome, which has implications for better design of gene-therapy delivery. Retroviral vectors are often used to introduce therapeutic genetic sequences into human chromosomes, such as in the delivery of Factor VIII for hemophili...Scientists characterize proteome of human cornea
...enmark. "Corneal infections by bacteria, fungi, or viruses are common disorders that can lead to corneal opacification. A group of inherited corneal disorders including granular and lattice corneal dystrophies are characterized by deposition of insoluble and opaque macromolecules in the cornea. Other disorde...New molecule may aid in production of biofuels and fungi-resistant plants
...y interfering with their chitin metabolism. Insect viruses need to degrade insect chitin for infection. Fungi may also be combated by degrading the chitin in their cell walls." More than one billion tons of chitin are produced by insects, fungi, and marine organisms every year. Despite this abundant product...Computer models aid understanding of antibody-dependent enhancement in spread of dengue fever
... triggered small increases in transmission it gave viruses an edge over other co-circulating dengue viruses that did not experience enhancement. Counter-intuitively, larger increases in transmission resulted ...Polymer gel can block toxic leakage problem in gene therapy
...to arrest toxic leakages of genetically engineered viruses that have plagued attempts to use gene therapy against cancerous tumors. The problem has been that viruses carrying anti-tumor genes have tended to leak from tumors, proving toxic to other body tissues. The...New possibilities for flu antiviral and vaccine research emerge from 'Spanish flu' virus
...ish flu virus is more closely related to avian flu viruses than other human flu viruses. Many experts say tha...ing stringent safety conditions designated for flu viruses and heightened security elements mandated by the CDC's Select Agent program. "We felt we had to re...Katrina floodwaters not as toxic to humans as previously thought, study says
...and chlorine. Instead, high levels of bacteria and viruses were the biggest human threat, not exposure to chemicals, Pardue and his associates say. The researchers obtained 38 floodwater samples from widespread sections of New Orleans, primarily in the area of the city known as the "East Bank," where the ma......h regulate the body's immune response to bacteria, viruses and other bugs. The discovery adds insight to the latest trend in lead research, as scientists shift their emphasis from the immediate public health threat to understanding the long-term burden on the body, said Michael McCabe Jr., Ph.D., associate ...