Enlisting genomics to understand flu evolution
... et al. found that a relatively uncommon strain of virus contributed its hemagglutinin gene (a highly varia...cognized by the host's immune defense system) to a virus common during the previous year. The reassorted virus suddenly became capable of infecting thousands...Achilles heel of the herpes virus possibly found
...ts haven't fully understood how the herpes simplex virus (HSV) manages to do all of this. And that has stoo...s may help explain why the oral and genital herpes virus has such a successful track record: The receptor, dubbed B5, is made by most cells for another purpo...New Vaccine To Be Used For First Time In Polio Outbreak Response
... in the country's capital Sanaa and suggesting the virus had spread across the country. Ongoing field investigations have identified additional suspected polio cases across the affected governorates in Yemen. Low immunization rates among Yemen's children may facilitate the spread of the virus. Experts are...Anthrax test, developed by army and CDC, receives FDA approval
...sed to identify B. anthracis. The gamma phage is a virus capable of entering bacterial cells and causing ce... readable result," Ezzell explained. "Wherever the virus is added to the surface of a culture plate that has been inoculated with suspicious anthrax colony g...'Mad cow' proteins successfully detected in blood
...sed to identify B. anthracis. The gamma phage is a virus capable of entering bacterial cells and causing ce... readable result," Ezzell explained. "Wherever the virus is added to the surface of a culture plate that has been inoculated with suspicious anthrax colony g...Study: Harmless virus kills some cancers
... is all it takes for a common, non-disease-causing virus to kill cervical, breast, prostate and squamous ce...chers. "Our results suggest that adeno-associated virus type 2 (AAV2), which infects the majority of the population but has no known ill effects, kills mult...Scientists turn tobacco against cancer
...made monoclonal antibodies could neutralize rabies virus and prevent disease in infected mice. They wanted to find out if plant-made antibodies could be effective for cancer immunotherapy. They first showed that plant-made monoclonal antibody purified from tobacco leaves could recognize, or bind to, human...Discoveries by UAB and Florida scientists may help transplanted organs survive longer
...y, Atkinson said, "was the use of adeno-associated virus as a way to deliver IL-10 into the body, allowing sustained levels of the molecule to be persistently secreted into the blood stream. The next step will be to evaluate the treatment to try to protect kidney transplants in non-human primates ?and if ...Harmless virus may hold key to more effective HIV drug discovery
...al to overcome drug resistance A simple, harmless virus might hold the key to the more effective and efficient development of HIV and anti-viral drugs, UCI chemical biologists have found. In order to better identify compounds that can outmaneuver a virus' effort to mutate and multiply, Gregory Weiss and ...Researchers seek to discover what really happens when a virus enters the body
...we really know what a body's host cell does when a virus infects it? Bell and Duca's collaboration is an ... of its faculty fellows, study the response as the virus moves outward. Their method differs from conventional laboratory studies of viruses that generally i...Identification of specific genes predicts which patients will respond to Hepatitis C treatment
...s a disease of the liver caused by the hepatitis C virus (HCV). About 230,000 Canadians are infected with i...feron. This treatment can currently get rid of the virus in only roughly 50% of persons infected with genotype 1, the most common genotype in North America a...Variation in HIV's ability to disable host defenses contributes to rapid evolution
...e, and might even promote further variation in the virus within patients. "This work elucidates new pathways which shape the evolution of the virus," says Viviana Simon, lead author of the study. ### Citation: Simon V, Zennou V, Murray D, Huang Y, Ho DD, et al. (2005) Natural variation in Vif function ca...New protein vital for immune response is found in surprise location
...ral diseases such as the flu, hepatitis, West Nile virus and SARS. The study is available online and will a...d elsewhere have previously found that when an RNA virus invades a cell, a protein called RIG-I first intercepts the virus and binds to viral genetic materia...Compound might defeat African sleeping sickness, clinical trial beginning this month
... a recent outbreak there of the Ebola-like Marburg virus remains under control. "The Swiss Tropical Institute will be responsible for selecting patients and carefully monitoring the trials," said Olson, who helped design and will oversee the study. She is an infectious disease expert who retired after a l...Fragment of yellow fever virus may hold key to safer vaccine
...and their colleagues have found the crucial bit of virus that people's immune systems need to spot and quas...ples from patients. In people, the mosquito-borne virus incubates for three to six days. Initial flu-like symptoms are followed by a brief remission of up t...High rates of sexually transmitted infections found in young drug users
...er institutions found high rates of herpes simplex virus 2 and syphilis among young drug users in Baltimore...c Health. The researchers examined herpes simplex virus 2 and syphilis test results in 543 heroin, cocaine and crack users from Baltimore, Md., aged 18-30 y...Hepatitis C responds best to combo of ribavirin and interferon, study concludes
...nflammation of the liver caused by the hepatitis C virus (HCV). It is transmitted primarily by blood-to-blo...ain cellular activities such their ability to kill virus cells and inhibiting the ability of viruses to make new copies of themselves and proliferate. Ribav...Most common lung cancers may begin in newly discovered cells
... cell lung cancers in people. A specially designed virus can activate the mutation in only a few cells. The... In this case, the mouse inhales a small amount of virus that activates the K-ras oncogene in some of the lung cells. Four years ago, Jacks's lab reported t......rongest association yet between a newly identified virus and the pediatric respiratory disease commonly kno...d Freiberg, determined the incidence of this novel virus in a sample of children under three years old with such respiratory infections. Nine hundred and for......partial correction to bleeding problems in mice A virus that typically infects insects could help with the... the outer layer, or "coat," from a baculovirus, a virus that infects butterflies and moths, onto another modified virus. This hybrid vehicle could more easi...