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Tag: "virus" at biology news

UCLA launches $20 million stem cell institute to investigate HIV, cancer and neurological disorders

... * HIV: UCLA scientists are exploring how the AIDS virus blocks stem cell function, as well as stem cell approaches to combating HIV disease. One potential therapeutic example includes inserting antiviral genes into blood-forming stem cells and reintroducing them into the body. As these blood cells develop...

Gene Signatures Predict Interferon Response For Multiple Sclerosis Patients

... division in neighboring cells—thus preventing the virus from reproducing—and triggering pathways that kill the infected cells. It's thought that interferon therapy may relieve symptoms associated with MS by correcting imbalances in the immune system that lead to disease. Interferon therapy produces change...

Norovirus, AIDS vaccine and Hepatitis Virus

...rhea and tested for the presence of norovirus. The virus was detected in 65 percent of the samples tested, ...e study the DNA of a simian/human immunodeficiency virus (SHIV) was made noninfectious by removing the gene that makes reverse transciptase (a protein the vi...

Antiretroviral therapy may prevent excess risk of some cancers in people with HIV

In people infected with human immunodeficiency virus (HIV), highly active antiretroviral therapy (HAART) may prevent most excess cases of Kaposi sarcoma and non-Hodgkin lymphoma, according to a new study in the March 16 issue of the Journal of the National Cancer Institute. Studies of people with acqu...

Viral protein influences key cell-signaling pathway

... shows that a protein produced by a cancer-causing virus influences a key signaling pathway in the immune cells that the virus infects. This stimulates the cells to divide, helping the virus spread through the body. The study,...

Stopping smallpox in its tracks: A new anti-viral approach

...this approach "may serve to turn the tables on the virus by interfering with the very pathways that are required for viral replication and extrusion." This study demonstrates, for the first time, that chemical inhibition of host cell signaling pathways exploited by infectious agents represents a new avenu...

HIV-1 spread through six transmission lines in the UK

...gests that HIV spread via at least six independent virus introductions and subsequent transmission chains. ...ain have been infected with human immunodeficiency virus type 1 or HIV-1 since the first identification of A ID S in 1982. Despite a recent increase in heter...

Gene therapy promising for growing tooth-supporting bone

... This study mixed BMP-7 genes with an inactivated virus in a gel-like carrier and injected it into wounds. Giannobile said using a virus, with the harmful effects turned off, harnesses the virus' ability to enter into cells and use their genetic machinery. Once inside the cell, the viruses help BMP-7 gen...

Marburg haemorrhagic fever in Angola update

...ve shown mortality rates ranging, according to the virus strain involved, from 53% to 88%. The only other l... more dramatically, in March. On 21 March, Marburg virus was detected in patient samples sent to the Centers for Disease Control and Prevention in Atlanta (U...

Promising new West Nile therapy cures disease in mice

West Nile virus alarmed Americans when it made its first U.S. appe... 16,000 Americans and killed more than 600. As the virus spread, medical investigators hastened research to develop an effective vaccine or therapy. None cur...

Anti cancer virotherapy well tolerated in first human administration, research finds

...i-cancer therapy based on the use of a common cold virus to control cancer cell growth has begun safety tes...ad injected a single dose of Coxsackie A21 (CVA21) virus directly into the advanced melanoma tumours of these patients with end stage disease. Both patients...

Researchers uncover sequence of major rice pathogen

...what Dean calls "hot spots" in the genome. "These virus remnants live in discreet parts of the genome and have high rates of recombination, which may be why the fungus can evolve new strains so quickly," Dean says. M. grisea undoubtedly produces toxins which may enable it to be a more effective pathogen....

Researchers make gains in understanding antibiotic resistance

...the drugs attack several sites at once. And if the virus mutates to avoid the effects of one drug, it still gets hit by another. However, in the case of these antibiotics, the binding sites are linked in one molecule. It's like a multi-drug treatment, but in one compound," he said. ...

Youth With HIV Take More Risks After New Meds Introduced

...d in 1996. The new drugs have successfully lowered virus levels and prolonged the lives of thousands of HIV...ents could mean more opportunities to transmit the virus to others, says Lightfoot. "Simultaneously, evidence suggests that many people living with HIV beli...

Biologists discover why 10% of Europeans are safe from HIV

...mutation (known as CCR5-delta32) that prevents the virus from entering the cells of the immune system but h...ubonic plague is a bacterial disease rather than a virus and is not blocked by the CCR5-delta32 mutation. Professor Duncan commented: "The fact that the CCR...

First North American Encapsulated Islet Transplant without Long-term Immune Suppression into a Patient with Type 1 Diabetes

...mutation (known as CCR5-delta32) that prevents the virus from entering the cells of the immune system but h...ubonic plague is a bacterial disease rather than a virus and is not blocked by the CCR5-delta32 mutation. Professor Duncan commented: "The fact that the CCR...

Live vaccines more effective against horse herpes virus

...lowing the recent deadly outbreak of equine herpes virus at Churchill Downs, home of the Kentucky Derby, a ... some 90 percent of infected horses, equine herpes virus type 1 (EHV-1) leads to a mild upper respiratory infection with fever, nasal discharge and fatigue f...

Shutting down the HIV assembly line

...ing a susceptible cell, the human immunodeficiency virus hijacks that cell's normal machinery to produce carbon copies of itself. New HIV particles roll off the cellular assembly lines, burst like bubbles out of the cell, and float off to invade other cellular factories. Vanderbilt University Medical Cente...

Turning viruses into allies against cancer

...ges of development, including modifications of the virus that causes measles and another, the herpes simple...cancer. In early clinical studies, the engineered virus -- developed by Biovex Ltd. under the trade name OncoVEX -- showed promise of causing necrosis (deat...

MUHC scientists describe genetic resistance to rampant virus

...s and persons infected with human immunodeficiency virus (HIV). Dr. Vidal believes her groundbreaking discovery increases the likelihood that therapies will be developed to fight CMV. ...

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