MRSA vaccine shows promise in mouse study
...ce against potentially lethal infections with five virulent S. aureus strains, the researchers report in the N...use of hospital-acquired infections, and USA400, a virulent community-associated strain that carries lung-damaging toxins. All five strains were resistant to m...St. Jude test of bird flu vaccine proves successful
...on in mice against lethal challenges with a highly virulent (Vietnam/1203/2004) H5N1 avian influenza virus. Mo...ed the DNA vaccine survived the challenge with the virulent H5N1 strain, while those that received a "blank" vaccine control did not survive. The vaccine also p...Solved: The mystery of flesh-eating bacteria's relentless attack
...otizing fasciitis. After injecting the mice with a virulent strain of Streptococcus of a type known as M14, is.... This may be one reason why some strains are less virulent than others; they might make more SilCR. "It would be interesting to study the amount of SilCR produ...Molecular anatomy of influenza virus detailed
...otential to identify particular features of highly virulent strains, and to provide insight into how antibodies inactivate the virus, and how viruses recognize susceptible cells and enter them in the act of infection. "Being able to visualize influenza virus particles should boost our efforts to prepare fo...Recurrence of a flu pandemic similar to infamous 1918 flu could kill 62 million
...s, the research team estimated that if a similarly virulent strain of flu virus were to strike today, about 62 million people worldwide would die. This could represent a devastating impact on global mortality, more than doubling deaths from all causes in a single year. However, only four percent of these f...A new understanding of how cells defend themselves against bacterial pore-forming toxins
...ey weapon in the attack arsenal of some common and virulent bacteria, such as Staphylococcus aureus, well-known for its role in hospital-acquired infections, Streptococcus pneumonie, responsible for middle ear infections and pneumonia, and Helicobacter pylori, implicated in ulcers. Pore-forming toxins compos...A wolf in sheep's clothing: Plague bacteria reveal one of their virulence tricks
The bacterium that causes the plague belongs to a virulent family of bacteria called Yersinia, a group that also includes a pathogen responsible for food poisoning. These bacteria insert into their host cells proteins and other virulence factors, which kill by -- among other things -- disrupting the cells' n...Experimental vaccine protects mice against deadly 1918 flu virus
...caused the 1918 pandemic and to protecting against virulent flu strains in the future, including the H5N1 avian flu virus. Details of the research are available online this week in Proceedings of the National Academy of Sciences. Gary J. Nabel, M.D., Ph.D., director of the Vaccine Research Center (VRC) at th...Stanford discovery may help predict when toxoplasma can be deadly
...ll in the china shop." The origins of the more virulent strains of Toxoplasma were first documented in a ...s can test whether the women have one of the more virulent strains, they can then better assess the risks to the fetuses. The group's further exploration of ...Resistance and genetic sensitivity to sleeping sickness
...on it induces takes effect after a few weeks. More virulent than the chronic form, its development cycle is also more rapid and, consequently, clinical detection can be made earlier. However, it is increasingly recognized that the existence of these two forms, the chronic one due to T. b. gambiense and the...Scientists find mutations that let bird flu adapt to humans
...ld be the organism that will trigger a pandemic of virulent human influenza. The avian virus has already changed dramatically from when it was first identified in 1997, says Kawaoka, who also holds an appointment at the University of Tokyo. "There are big differences between the virus first found in 1997 a...Queen bee promiscuity boosts hive health
...ent, in which we inoculated colonies with the most virulent disease of honeybees that is known, the dreaded Am...eens) with water tainted with spores of the highly virulent bacterium that infects bee larvae and causes the disease American Foulbrood. Sure enough, the more...Researchers develop technologies to devour food pathogens
... were reported due to spinach contamination with a virulent strain of E. coli. "What is happening is unacceptable," Linton said. Bhunia's technology is further described in an article published this summer in the Journal of Biomedical Optics. Linton and Morgan have been working with chlorine dioxide for y...The subtleties of tropical forest demise
...hose that have only recently appeared, such as the virulent chytrid-fungus pathogen that is decimating rainforest amphibians throughout the tropical world. (2) Those that are growing rapidly in importance, such as destructive surface fires in tropical forests. (3) Those that are poorly understood, such as the...'Protecting virus' offers instant flu protection and converts flu infections into their own vaccines
...ader. In effect the protecting virus converts the virulent virus into a harmless live vaccine. Research indicates that the 'protecting virus' would have the same beneficial effect whatever strain of influenza is infecting you. This is because the coat of the virus is irrelevant to the protection process ?...New findings could lead to vaccine for severe malaria
...smodium falciparium is the name of by far the most virulent of the four malaria parasites that infect man. It is particularly dangerous in that it also infects the placenta of pregnant women, with fatal consequences for both her and the foetus. This, combined with the often feeble medical resources of malaria...Reminding doctors which antibiotics to prescribe cuts C. difficile infection rates
... rates are rising rapidly in the UK and a new more virulent strain has recently been identified2 A 2005 study by the Healthcare Commission3 found that 38% of NHS Trusts did not restrict broad-spectrum antibiotic use, despite the known association between these compounds and CDI. BACKGROUND Drugs such...Scientists identify specific enzymes that make meningitis hard to fight
...death and the defeat of the bacteria. However, the virulent meningitis bacteria are able to repair this harmful damage and are therefore unaffected by the body's defences. The research team found that the two enzymes essential to the bacteria's repair mechanism are AP endonuclease and 3'-phosphodiesterase....Pacific Rim researchers to collaborate on distributed bioinformatics analysis of avian flu
...nto the interactions among factors determining how virulent a particular type of flu might be, and this will require a lot of raw computing power," said Maqsudul Alam, director at the Advance Studies in Genomics, Proteomics and Bioinformatics, College of Natural Sciences, University of Hawaii. "This will allo......mmune response may be a shared feature of the most virulent influenza viruses. In the new study, conducted ...s, suggesting the agent somehow sets the stage for virulent infection: "Somehow, early in infection, this virus does something to the host that allows it to gro...