viral 2 9

Tag: "viral" at biology news

Ancient DNA helps UF researchers unearth potential hemophilia therapy

...y, the gene would be unable to enter the cell. But viral gene therapy has been associated with medical complications, and a few human patients have died as a result. Instead, UF researchers used a novel nonviral approach, employing a strand of DNA present in modern-day fish called a transposon to transpor...

'Virus chip' detects new virus in prostate tumors

...iously unknown viruses and potentially uncover new viral causes for disease, the researchers say. While mos... men with mutations in both copies of their RNASEL viral defense gene, eight of them, or 40 percent, contained the virus, while the virus was found in only o...

Simple idea to dramatically improve dengue vaccinations

...ng pain and was "the most important mosquito-borne viral disease affecting humans" in 2005 according to the U.S. Centers for Disease Control. The study, from bioengineers and physicists at Rice University, appears in the March 24 issue of the journal Vaccine. The study suggests that the multi-site vaccina...

Immune response to HIV in the brain

...ecular techniques, the team found both a low-level viral infection in the brain and immune cells that had i...s a double-edged sword, protecting against rampant viral replication in the brain but leading to brain dysfunction." The paper was published in the April 2...

Experimental vaccine protects nonhuman primates when given after exposure to Marburg virus

...ecular techniques, the team found both a low-level viral infection in the brain and immune cells that had i...s a double-edged sword, protecting against rampant viral replication in the brain but leading to brain dysfunction." The paper was published in the April 2...

Learning to love bacteria: Stanford scientist highlights bugs' benefits

... the intriguing idea that persistent bacterial and viral infections have benefits. Stanley Falkow, PhD, the Robert W. and Vivian K. Cahill Professor in Cancer Research, is publishing his thoughts on this topic in an essay in the Feb. 24 issue of the journal Cell, in which he asks, "Is persistent bacterial...

Scientists look to the Bahamas as a model for coral reef conservation

... the intriguing idea that persistent bacterial and viral infections have benefits. Stanley Falkow, PhD, the Robert W. and Vivian K. Cahill Professor in Cancer Research, is publishing his thoughts on this topic in an essay in the Feb. 24 issue of the journal Cell, in which he asks, "Is persistent bacterial...

UW scientists unravel critical genetic puzzle for flu virus replication

...uce vaccines. Researchers have been trying to make viral vectors using nine genetic segments, a strategy that has never worked, Kawaoka notes. "To develop an influenza virus vector, we have to stick to this eight-segment concept," he says. Such a strategy may be useful for developing vaccines for a range...

Boosting newborns' immune responses

...n TLR8 was stimulated by various agents that mimic viral antigens, the cells produced normal, adult levels ...t levels of TNF-alpha in response to bacterial and viral triggers. "In the future, we could try to block adenosine in newborn animals to see if this helps p...

Ocean virus identified in human blood samples

...chool, and AVI BioPharma. The association between viral infection and the presence of a disease of unknown...nclude encephalitis and spontaneous abortion. The viral group being studied is the genus Vesivirus, one of four genera in the Caliciviridae viral family. So...

Immune system response to viral DNA is unique

...lished that such a pathway exists for detection of viral RNA inside infected cells," Stetson said. "In cont...nisms of antiviral responses and how cells discern viral and self-DNA." ...

Mice studies illustrate potential of chimp/human antibodies to protect against smallpox

...s injection, which the researchers correlated with viral replication in the lungs. In contrast, mice injected with either of the two types of hybrid antibodies did not lose weight. Since there was no difference in the protective abilities between the two hybrid antibodies, the researchers used 8AH8AL to d...

Defective immune system response to smallpox vaccine detailed in new study

...lement, the skin cells successfully controlled the viral replication. Dr. Leung and his group then looked more closely at why vaccinia infection fails to induce LL-37 production in atopic dermatitis skin. Comparing immune responses of skin cells grown in the lab from healthy volunteers and from people wit...

Waking a sleeping virus

... in fighting viruses is to block the activation of viral genes," says Patrice Morand, a physician at the Un... is that they only interrupt the late phase of the viral cycle. Since ZEBRA is essential to the first steps, waking the virus, blocking it would be much bett...

International HIV/AIDS trial finds continuous antiretroviral therapy superior to episodic therapy

...ive volunteers were assigned at random to either a viral suppression strategy, in which antiretroviral ther...ART) was taken on an ongoing basis to suppress HIV viral load; or a drug conservation strategy, in which ART was started only when the levels of key immune c...

'Nano-keys' bind cell receptors and trigger allergic reactions

...her immune responses, high cholesterol and perhaps viral infections. By understanding a membrane's role in cell function, she explained that these nano-keys could interfere with responses via the membrane interactions, rather than just targeting proteins to block responses. This could lead to designing li...

Viral protein helps infected T cells stick to uninfected cells

.... The greater stickiness happens because the p12 viral protein causes special adherence proteins found on the surface of T cells to cluster in large groups ?something that normally happens when T cells touch to communicate with one another during an immune response. The findings also suggest that a dru...

Faster immune system testing set to improve poultry quality

...al poultry producers worldwide. The major cause is viral infection. All viruses can cause immunosuppression to varying degrees but Marek's disease, infectious bursal disease and chicken anaemia are particular concerns. A simple test to identify flocks that have been immunosuppressed by non-apparent infecti...

Animals can change genes quickly to keep up with viral ingenuity

...molecular defenses against viruses by homing in on viral genetic material and directing its enzymatic destr... evolve countermeasures of their own to resist new viral strategies. The new research provides evidence for such rapid evolution of some RNAi genes: The rese...

Minor mutations in avian flu virus increase chances of human infection

...ein hemagglutinin (HA) on the virus surface. These viral HAs bind to host cell receptors containing complex...to fuse with the membrane of the host cell so that viral genetic material can be transferred to the cell. The switch from ?2-3 to ?2-6 receptor specificity...

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