viral 2 5

Tag: "viral" at biology news

Identification of specific genes predicts which patients will respond to Hepatitis C treatment

... about 170 million people worldwide. Over time the viral infection leads to liver damage, cirrhosis and/or ... groups were well matched with respect to age, HCV viral load (number of viral particles circulating in the blood), and liver disease activity. In order to ...

Variation in HIV's ability to disable host defenses contributes to rapid evolution

...pid evolution. Understanding how host defenses and viral countermeasures contribute to that evolution is vital. Host cells produce two proteins that mutate HIV DNA and interfere with the virus's ability to replicate. But HIV produces a protein, called Vif, that can disable the two defensive proteins. Vif...

New protein vital for immune response is found in surprise location

... vital to the immune system's ability to fight off viral infections but also has been found in an unexpecte... to new therapies aimed at preventing and treating viral diseases such as the flu, hepatitis, West Nile virus and SARS. The study is available online and wil...

Retroviral resistance gene found

...re able to enter the host cells and synthesize the viral DNA, but were excluded from entering the host cell...1 interferes with intracellular trafficking of the viral preintegration complex and traps the viral DNA in the cytoplasm. We hope that learning more about th...

Fragment of yellow fever virus may hold key to safer vaccine

...oup has identified a specific region on one of the viral proteins that elicits an immune response. Antibodi...s more attention, but yellow fever is the original viral hemorrhagic fever. It strikes more than 200,000 people a year, mostly in Africa, killing about 30,00...

A novel virus for croup

...l also contribute towards the clarification of the viral causes of lower respiratory tract infections generally; causes that have not always been apparent despite the frequency of such infections amongst children. ...

Elevated temperature enhances success of viral cancer therapy

...trates that tumor cells are even more sensitive to viral therapy after they have been incubated at an eleva...have a significant impact on the future success of viral strategies for cancer therapy. ONYX-015 is a mutated adenovirus that undergoes selective replicatio...

Gene Bridges And Covalys To Develop Restriction-Enzyme-Free SNAP-tag Gene Fusion Kits

...cation of BACs and E. coli chromosomes, as well as viral engineering. Gene Bridges, an EMBL spin-off, is headquartered in Dresden, Germany and maintains a commercial centre is in Heidelberg. For more information, visit: www.genebridges.com ...

Scientists show that tick-borne flaviviruses use a novel mechanism to evade host defenses

... inflammation of the brain. Hemorrhagic fevers are viral infections that cause capillaries to burst, leading to unusual bleeding on or under the skin or in various organs. The study released this week online in the Journal of Virology describes how a single virus protein--NS5--from the tick-borne Langat f...

Engineered molecule amplifies body's immune response

... severe case, the children die in infancy of fatal viral infections. In less severe cases, they later devel...its of hyper-responsive Stat1 in vivo for treating viral infection and cancer. They are also screening for drugs that might increase Stat1 responsiveness. T...

Secrets to antibody's success against West Nile Virus surprise scientists

...netic material that can then be assembled into new viral particles or virions and sent out to infect other host cells and reproduce. But with the viral reproduction process blocked by the antibody, scientists suspect that the host cell eventually destr...

Mass production of human papillomavirus could lead to gains against cervical cancer

...ating does the virus emerge as distinct, infective viral particles, called virions. Thus, said Ahlquist, in...e available approaches required a fully functional viral genome to make infectious virus." Two discoveries made it possible to develop a mass-production tec...

Gene therapy to lower blood pressure just enough

...mount of ANP a cell makes was needed. The special viral vector developed by O'Malley and his colleagues co...er the body will accept repeated injections of the viral vector or whether its immune system eventually react against it, said O'Malley. ...

Neurologix announces positive results of gene therapy clinical trial in Parkinson's disease

... Phase I trial is the world's first study to use a viral vector (the non-pathogenic adeno-associated virus,...n dose cohort) of the AAV (adeno-associated virus) viral vector with a human GAD gene (cDNA) were then infused at 0.5 microliters/minute, together with 15 m...

Bird samples from Mongolia confirmed as H5N1 avian flu

...on Society (WCS). It is the first instance of this viral strain occurring in wild migratory birds with no apparent contact to domestic poultry or waterfowl. Present in Mongolia for a health survey of wild bird populations in the south and north of the country, WCS field vets Drs. William Karesh and Mart...

Primate virus jumps species barrier to humans for first time in Asia

...ing human disease. "The issue of primate-to-human viral transmission has been studied extensively in Afric...man-primate contact. The vast majority of previous viral transmission research focused on bushmeat hunting and consumption, a practice in which local residen...

Quantum dots provide a faster, more sensitive method for detecting respiratory viral infections

...ult, when quantum dots come in contact with either viral particles or infected cells they stick to their su...iruses. There are specific medicines to treat some viral infections and there are definitely antibiotics to treat bacteria. Yet current detection tests take ...

Hopkins scientists uncover 'tags' that force proteins to cell surface

...nes that are seven to nine blocks long to identify viral proteins or other immune triggers," explains Li. Also, the number of possible combinations of eight-block-long protein segments provides a "reasonable number" to sort through -- 25 billion or so -- given today's high throughput technologies. To mak...

Several minute intermediate stage in virus-cell fusion discovered; opportunity for drug development

... will open and some won't. It's a crucial point in viral entry because it's critical for the pore to enlarg...sed by Young and Melikyan last year to investigate viral infection in a manner as close to 'real life' as possible. The researchers filmed the microscopic vi...

UIC developing drug for SARS

... symptoms have started, the drugs could reduce the viral load and ameliorate the disease." Like HIV, the SARS virus multiplies rapidly, hijacking the machinery of the cells it infects to clone itself over and over again. One of the first steps in that process is the production of a long chain of proteins...

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