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Tag: "viral" at biology news

U-M team recovers ancient whale in Egyptian desert

...crucial time it takes to diagnose the bacterial or viral cause and administer the proper antibiotic. "Here's a patient group, quite commonly found in emergency rooms around the country, who would do well if they could just have their core body temperature taken down in order to buy them time until the pat...

Scientists identify genetic pathways essential to RNA interference

...nts and animals and may help control resistance to viral infection, among other functions. For the current... RNAi that may underlie some cancers or be used in viral replication may offer further clinical potential. Along with Kim, the study's co-first authors are ...

Youth With HIV Take More Risks After New Meds Introduced

...n of HIV, like unprotected sex, are less risky" if viral levels are low, she adds. Although some studies suggest a shift toward risky behavior in adults in the post-HAART era, (see http://www.cfah.org/hbns/newsrelease/safe_sex11-01-01.cfm), Lightfoot and colleagues are among the first to examine whether H...

Biologists discover why 10% of Europeans are safe from HIV

...a32 mutation to its protection from another deadly viral disease, acting over a sustained period in bygone ...e Black Death to values today of 1 in 10. Lethal, viral haemorrhagic fevers were recorded in the Nile valley from 1500 BC and were followed by the plagues o...

First North American Encapsulated Islet Transplant without Long-term Immune Suppression into a Patient with Type 1 Diabetes

...a32 mutation to its protection from another deadly viral disease, acting over a sustained period in bygone ...e Black Death to values today of 1 in 10. Lethal, viral haemorrhagic fevers were recorded in the Nile valley from 1500 BC and were followed by the plagues o...

Shutting down the HIV assembly line

...oteins take in order to come together and create a viral particle. "The assembly process is just one part ...ep along the way is required to make an infectious viral particle." Spearman's team has focused on a protein called "Gag," the major HIV structural protein....

Turning viruses into allies against cancer

...surviving cancer cells released during the initial viral attack, essentially preventing the spread of these cells to other parts of the body. "This aims to treat metastatic disease and reduce tumor recurrence," said Robert Coffin, Ph.D., chief scientific officer at Biovex Ltd. While this has not been demo...

MUHC scientists describe genetic resistance to rampant virus

...read virus, cytomegalovirus (CMV)--a member of the viral group that causes some of the world's most prevalent diseases, such as herpes, chicken pox and mononucleosis. The groundbreaking research published in Nature Genetics last week, provides a roadmap for the development of human therapies for CMV, which...

Measuring hormone cuts antibiotic use in half in pneumonia patients

...vated in patients with bacterial infection but not viral infection or other inflammatory diseases, Dr. Tamm...ow procalcitonin levels, and were presumed to have viral pneumonia; they were not given antibiotics. The remaining 85% had high levels and were started on an...

Defensins Ward Off HIV In Two Ways

...lood cells are removed) and under conditions where viral burden is low, alpha-defensin-1 directly inactivates HIV virus. When serum is present, alpha-defensin-1 acts on vulnerable cells to block HIV infection at the stage when the virus is taken up by the cell and begins replicating itself and integrating ...

Secret of smallpox's success may lead to bioterror cure

... have a powerful tool for fighting a host of other viral pathogens, including HIV. Jacobs has received a $...o the vaccinia virus by completely eliminating the viral gene that allows pox viruses to hide. The more visible the vaccinia virus is to the immune system, t...

Supercomputers to focus brains on AIDS dilemma

...tive against AIDS. By blocking the activity of the viral enzyme HIV protease, these protease inhibitors brought greatly extended life-spans to patients who previously faced early deaths. Structural biology and molecular dynamics computer simulations played an important role in these discoveries. However, ...

Basis for DNA ejection from single phage particles

...ugh the release of pressure accumulated within the viral particle itself. Almost all phages (also known as...ormed of a capsid structure, or head, in which the viral genome is packaged during morphogenesis, and a tail structure that ensures the attachment of the pha...

Gladstone investigators discover how resting T cells avoid HIV infection

...tists thought that A3G had to squeeze into new HIV viral particles in order to produce its antiviral effect...ted activated CD4 T for incorporation into the new viral particles. Thus, this antiviral action of A3G that only occurs in activated T-cells can be overcome ...

Gene therapy cures inherited liver disease in rats

...us to carry the gene into the animal's cells. This viral vector, as it is called, was manipulated so that i...f the lack of genes in this area of the cell. The viral vector itself is important because it has no long term effect. It does not become part of the geneti...

Scientists discover how Ebola virus infects cells

...hagic fevers. "Finding medical countermeasures for viral hemorrhagic fevers is a global public health priority because not only do these diseases occur naturally but they also have the potential to be unleashed by bioterrorists," says NIH Director Elias A. Zerhouni, M.D. "This new research sheds light on ...

Molecular fossils uncover link between viruses and the immune system

...e structure. One plausible explanation may be that viral building blocks served as precursors for the evolu...ology, which have permitted detailed comparison of viral structures in atomic detail. Such comparison led to the discovery that viruses without any sequence ...

WHO suspends Marburg work, appeals for new funds

...s, the single most important factor in controlling viral haemorrhagic fevers is the engagement of affected communities as partners in control. To achieve this engagement, local belief systems about the causes of disease and traditional rituals for mourning the dead must be respected. When the public unders...

How A Latent Virus Eludes Immune Defenses

...ividing cells and doesn’t produce any proteins. No viral proteins means no red flags for immune cells. If t...ell and triggers an immune response—that helps the viral protein evade the killer T cells that could destroy it. Lab studies show that the amino acid element...

Touching Molecules With Your Bare Hands

...ividing cells and doesn’t produce any proteins. No viral proteins means no red flags for immune cells. If t...ell and triggers an immune response—that helps the viral protein evade the killer T cells that could destroy it. Lab studies show that the amino acid element...

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