viral 2 10

Tag: "viral" at biology news

Tool developed to silence genes in specific tissues using RNAi

...Ai is used by cells in many life forms to identify viral RNA, which often enters a cell as a double strand..... RNAi, therefore, recognizes the double strand of viral RNA as different, and sets in motion cell machinery that destroys the invading RNA. This involves cu...

Flu not the only germ threat this time of year

...ever mind Strep in the throat and ears, or Norwalk viral agents that attack the GI system, and so on. While the world's attention has migrated to bird flu, not a single person in the western hemisphere has contracted the deadly form of the disease. And though "regular" flu is still a potent threat, expect...

Avian influenza virus in mammals spreads beyond the site of infection to other organ systems

...hoid, and endocrine) for the presence of virus and viral protein. As expected, all cats were infected with...ssues revealed cellular damage at sites containing viral proteins, providing an explanation for the increased severity of disease in humans. These data unde...

Gene-specific Ebola therapies protect non-human primates from lethal disease

...tudy's authors, antisense drugs are useful against viral diseases because they are designed to enter cells ...ication. The drugs, which act by blocking critical viral genetic sequences, may be more potent than anti-virals such as protease inhibitors, which seek to in...

Research details how a virus hijacks cell signals to cause infection

...on of the heart in children and adults, as well as viral meningitis, which inflames the lining of the brain...fits, by contributing to future therapies to block viral infections. For now, we have learned more about cell functions, and how viruses may evolve unexpecte...

Access to antiretrovirals unlikely to reduce HIV infection rates

...re likely if the HIV-positive partner has a higher viral load. Because antiretrovirals therapy (ART) slows AIDS progression and reduces viral load in infected individuals, the drugs not only improve the health and prolong the life of those wh...

How can we protect patients with weakened immune systems from influenza?

... outer coating from year to year, a process called viral drift, which is why new flu vaccines are developed...mpletely new type of virus such as this represents viral shift, and is usually far deadlier because there is no pre-existing immunity in the population. Fu...

Study shows that cells have a natural defense against HIV

...herapies and would probably be less susceptible to viral drug resistance ?an increasingly urgent dilemma for patients and doctors. Currently, doctors treat people with AIDS using combinations of drugs that target the virus itself. These drugs do not eliminate HIV from the body, but they do block its abil...

Biologists visualize protein interaction that may initiate viral infection

...rchers might want to find ways to treat or prevent viral infections, but in order to do that we first have to learn how viruses work and how they initiate infection." The findings are detailed in a research paper to appear on Feb. 10 in the journal Cell. The research was carried out by Elena Pokidysheva a...

Plant-derived vaccines safeguard against deadly plague

... The group's results are the first to use Icon's viral expression system that adapts the tobacco mosaic virus (TMV) to produce a plant-based vaccine against plague. TMV, a common scourge of the plant world, causes widespread plant disease and can damage and mottle the leaves, flowers and fruits of whole ...

U of S researchers develop new vaccine candidate against hepatitis C

...e, in the same patient." The VIDO vaccine uses a viral protein that is common among different strains, ensuring that the vaccine will be effective against them. The researchers exposed dendritic cells in vitro to a HCV protein. The cells were also exposed to a strong immune stimulator to increase the i...

Viral 'fitness' explains different resistance patterns to aids drugs

... appear to be explained by the different levels of viral "fitness" of the drug-resistant HIV, say AIDS rese...type of medication also factors in. Differences in viral fitness of mutated resistant virus occur between different classes of antiretroviral drugs, said Ban...

AIDS drug from sunflowers

...ne of the few substances known today which inhibit viral integrase ?this is an enzyme which is essential if the pathogen is to reproduce.' In contrast to other enzymes medical experts expect there to be only a few side-effects from such integrase inhibitors. In the pharmaceuticals industry they are therefo...

Scientists force viruses to evolve as better delivery vehicles for gene therapy

...d Brian Kaspar, decided to speed up the process of viral evolution and direct the change in a way that woul...or Quantitative Biomedical Research (QB3). "In the viral realm, this approach is essentially untapped." This technique could be used to improve many other c...

Cyclosporine inhibits hepatitis C virus in vitro

...irus (HCV) achieved significantly better long-term viral response when taking the immunosuppressive agent Cyclosporine along with interferon-ribavirin combination therapy. Cyclosporine also showed efficacy against Hepatitis C virus in vitro. The results of this study appear in the January 2006 issue of L...

Scientists identify molecular structure of key viral protein

...rsity have determined the molecular structure of a viral protein, the parainfluenza virus 5 fusion (F) prot...ll allow us to better inhibit this key part of the viral life cycle." Tens of thousands of different proteins are at work in the human body, each folded int...

New vaccine for condition that kills 500,000 children a year

...t can safely prevent 98 percent of severe cases of viral diarrhea and vomiting that account for 2 million hospital visits and 500,000 pediatric deaths each year worldwide. In one of the largest pre-licensure vaccine clinical trials ever conducted worldwide, research championed by an Eastern Virginia Medic...

Researchers use mass spectrometry to detect norovirus particles

...ovirus--a category B bioterrorism agent--and other viral public health threats. The study is published in t...cteristic particles, or peptides, belonging to the viral coat protein, the virus can be positively identified by matching the results to entries in genetic d...

Ancient ants arose 140-168 million years ago

...ovirus--a category B bioterrorism agent--and other viral public health threats. The study is published in t...cteristic particles, or peptides, belonging to the viral coat protein, the virus can be positively identified by matching the results to entries in genetic d...

Unraveling the viral mechanism

...ues identified 12 protein copies that make up this viral motor. Chiu anticipates using the same technique to study other spherical viruses as soon as he can obtain the computer power to study larger structures. Soon, he said, he hopes to be able to study the interactions of virus and cell more closely. O...

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