New light microscope sharpens scientists' focus
...imately enable scientists to get a molecular level view of how proteins interact with one another inside cells. These are the interactions that drive cellular activity, and watching them in action will be important to understanding the interface between molecular and cellular biology. "As the PALM tech...Light guides flight of migratory birds
...ries in a rotated magnetic field, where they had a view of the whole sky, including the horizon. Once migr...here birds were exposed to the cue conflict with a view of the horizon, they did recalibrate their magnetic compass -- just as was previously observed only ...Structure determined for p53 tumor suppressor protein as bound to DNA for anti-cancer activity
...to its anti-cancer activity. Clearly, a detailed view of the p53 protein in direct contact with DNA could provide important insights into preventing and treating an array of human cancers. To date, however, despite having learned a good deal about the protein's biochemistry over the years, scientists ha...Molecular DNA switch found to be the same for all life
...eir E.coli study. "This work provides the first view of the mechanical transitions in ORC driven by ATP in a higher organism," said Nogales. "While our studies have not yet shown the initiator wrapped around the DNA, the structural similarity to the DnaA initiator found in the E.coli study suggests tha...Study identifies new role for breast cancer susceptibility gene
...signaling within the tissue microenvironment. This view will extend BRCA1's tumor suppression function to the surroundings that influence the fate of neighboring cells and fortify the pathogenic relevance of its defect to neoplastic growth," concludes Dr. Lee. ...Breast stem cells have features similar to 'basal' tumors
...cer is not simply a single disease. Scientists now view breast cancer as a heterogeneous disease, made up of various subtypes. This observation has led to speculation that breast tumours are derived from different cell types that could include the breast stem cell or its descendents that have suffered gen...Ecologists home in on how sperm whales find their prey
Ecologists have at last got a view of sperm whales' behaviour during their long, deep dives, thanks to the use of recently developed electronic "dtags". According to new research published in the British Ecological Society's Journal of Animal Ecology, sperm whales ?like bats ?use echo...Nutrition a major factor in rise in twin pregnancies
The commonly held view that IVF is the only culprit in the steady increase in the numbers of twins born over the past thirty years was challenged by a scientist speaking at the 22nd annual conference of the European Society of Human Reproduction and Embryology in Prague, C...MIT 'seeing machine' offers hope to blind
...ually challenged like her, to access the Internet, view the face of a friend, "previsit" unfamiliar buildi...ring's doctors. Participants used the machine to view 10 examples of Goldring's visual language. A majority - six - interpreted all 10 "word-images" corre...A switch between life and death
...onto to control. This will provide a more complete view of the Hippo pathway and may provide insights into the central role it plays in tissue growth and cancers in humans and other organisms. ...New MRI technique quickly builds 3-D images of knees
...h component of the image, so that a technician can view any aspect. High-resolution 3-D images are important not only from diagnostic and clinical standpoints, but also to help patients better understand their health conditions, says Block. "If you could actually look at a 3-D model from different persp...In a technical tour de force, Salk scientists take a global view of the epigenome
... will appear in a forthcoming issue of Cell. Our view of heredity has largely been written in the language of DNA, but recent discoveries in a field known as epigenetics - the study of heritable changes in gene function that occur without changing the letters of the DNA alphabet - show that how a cell "...U of MN uses robotic surgery techniques in cardiac cell therapy research
...er anesthesia. It also offers surgeons a magnified view of the heart and allows them to target the cell infusion more precisely. Harald Ott, M.D., co-leader of this study, now a surgery resident at Massachusetts General Hospital in Boston, pointed out, "Currently these types of cell therapies, in which ...UC San Diego biologists solve plant growth hormone enigma
...n was made did not really matter. The widely held view was that auxin could just be transported wherever it was needed. Not so, because turning auxin off in specific tissues of the plant led to defects in those tissues, while the rest of the plant appeared normal. "Knowing which auxin genes are activat...APS lecturer shows rare video of 'teacher-student' immune cell interactions in live animal
... Until recently, there has been no way to directly view much of this complex cellular teamwork in vitro and in real time. The von Andrian videos provided a real-time look at what happens inside a mouse lymph node when a foreign microbe enters the body. The videos were made possible by recent technologica...Researchers identify genes in fruitflies that may shed light on human cancer spread
...ell migration and simultaneously captured a global view of all the genes turned on when cells are on the move. The study, to be published April 3 in Developmental Cell, has implications for understanding cell migration and perhaps controlling cancer cells that move similarly to spread beyond an original......o see the same things again and again." Vermeij's view contrasts with that put forward by the late Stephen Jay Gould and others, who argued that the history of life is so dependent on improbable events and includes so many possible paths that the chances of repetition are vanishingly small. Vermeij argue...Alaska seal pup diet may hold key to decline of population
...and Evolutionary Physiology, 492.3/board #C768. On view 7:30 a.m. - 6 p.m. in the Convention Center Exhibit Hall. Research was by Lori Polasek and Shannon Atkinson of the University of Alaska, Fairbanks and Alaska Sealife Center, Seward, and Anne Hoover-Miller of the Alaska Sealife Center. The research i...Nanopore method could revolutionize genome sequencing
...the problem. "We don't think of it as DNA, we view it as a bunch of atoms and electrons that behave in ways we can predict and manipulate," said Di Ventra. ...Are dancers genetically different than the rest of us? Yes, says Hebrew University researcher
... This finding is not surprising, says Ebstein, in view of other studies of musicians and athletes, which also have shown genetic differences. Ebstein and his colleagues found in an examination of 85 dancers and advanced dancing students in Israel variants of two genes that provide the code for the serot...