Biologists probe the machinery of cellular protein factories
...ed he was right. "It was a completely heterodox view when we first proposed it, but it is now the accepted paradigm," said Noller, who directs the Center for Molecular Biology of RNA at UCSC. "Our latest results confirm that the ribosomal RNA is really the key to ribosome function. The proteins are als...Does missing gene point to nocturnal existence for early mammals?
...time wholly nocturnal creatures. "The classical view of how the eye sees is through photoreceptive cells in the retina called rods and cones," explained Dr Jim Bellingham, who led the research at The University of Manchester. "But, recently, a third photoreceptor was discovered that is activated by ...Pressured by predators, lizards see rapid shift in natural selection
Countering the widespread view of evolution as a process played out over the course of eons, evolutionary biologists have shown that natural selection can turn on a dime -- within months -- as a population's needs change. In a study of island lizards exposed to a new predator, the...New HIV statistics indicate increasing toll of AIDS on African American community
... NMAC's chair emeritus. "There is a danger that we view AIDS as a problem that only affects Africa when it remains a real and growing danger in our own backyard. That kind of complacency is killing people and it has to stop. This plan of action shows us the path forward to reversing this national dispar...Does natural selection drive the evolution of cancer?
...rests and meadows, oceans and streams. This is the view of researchers in an emerging cross-disciplinary field that brings the thinking of ecologists and evolutionary biologists to bear on cancer biology. Insights from their work may have profound implications for understanding why current cancer therap...Scientists get best look ever at water-life connection
...terium, Staphylococcus. The key to getting a good view of the interaction was to precisely locate an optical probe on the protein surface. They inserted a molecule of the amino acid tryptophan into the protein as a probe, and measured how water moved around it -- a technique Zhong began to develop when h...Innovative movies show real-time immune-cell activity within tumors
... cells, and killing them. Insights from this new view of the body's on-board defenses against cancer may open the way for improved immunotherapies to treat the disease. With a series of movies made under different experimental conditions, the researchers resolved important questions about the mechanis...To elude bats, a moth keeps its hearing in tune
...detection by moths" The authors point out that, in view of the vast diversity of bat calls, this is to be expected. ...Proteins anchor memories in our brain
...eins as "self." The research confirms an emerging view that autoimmunity can start in this cradle of the immune system, and not only at the sites where autoimmune diseases emerge, such as the pancreas in the case of type 1 diabetes, or the joints in rheumatoid arthritis. The discovery, from a mouse mod...Autoimmune disease triggered if T cells miss a single protein early on
...eins as "self." The research confirms an emerging view that autoimmunity can start in this cradle of the immune system, and not only at the sites where autoimmune diseases emerge, such as the pancreas in the case of type 1 diabetes, or the joints in rheumatoid arthritis. The discovery, from a mouse mod...'Nymph of the sea' reveals remarkable brood
...kable discovery provides an unequivocal and unique view of parental brood care in the invertebrate fossil record, it allows gender to be determined in an animal as old as the Silurian period of geological time, and indicates a remarkably conserved egg brooding reproductive strategy."...International team analyzes human genetic variation in key immune region
... other genomic efforts, to provide a comprehensive view of genetic variability in the human MHC. ...Most widely used organic pesticide requires help to kill
... report's authors, Jo Handelsman, of the long-held view of Bt's mode of killing. "What was proposed as a hypothesis in one paper became cited as proven in another and no one seemed to go back to the original literature until now." Handelsman is a Howard Hughes Medical Institute Professor in the UW-Madis...Better sludge through metagenomics
...ossibilities of the wastewater environment, with a view to understanding how the system works and predicting and averting failures or crashes. "This is a first step in a much broader strategy employing a systems biology approach to the study of microbial communities with the goal of designing predictive...USC team reveals structure of APOBEC family protein
...of Southern California have provided the first 3-D view of a protein from an enzyme family that, through its ability to mutate genes, can both help and hinder human health. Reporting in the Dec. 24 online edition of Nature, a USC team led by Xiaojiang Chen revealed the "unusual" crystal structure of the...When nerve cells can't make contact
...nimal model will be possible." From the point of view of the geneticist, the scientists in Göttingen have the best known animal model for autism worldwide. However, there is a limitation: only very few cases of autism are caused by neuroligin mutations and, with few exceptions, nobody knows which geneti...Killing brain tumors from within: A 'Trojan horse' approach
...hat the project has great potential, especially in view of the fact that over-expression of EGF receptors is involved in over 25 % of all types of cancers. The strategy developed to combat GBM can also be applied to other types of receptors found on cancerous cells, he added. Last year, Prof. Levitzki...Parental genes do what's best for baby
...at The University of Manchester say the prevailing view that maternal and paternal genes compete for supremacy in their unborn offspring fails to answer some important questions relating to child development. In fact, rather than a parental power struggle, the researchers suggest that certain offspring...Inheriting a tendency to brain infection
... his opinion, scientists will increasingly need to view common infectious diseases through the lens of such primary immunodeficiencies. "Understanding the genetic basis of the failure of the immune system should make it possible to devise novel ways to make it succeed," he said. Since the mid-1950s,......ightly separated from the dodder seedlings, out of view so to speak, in a set-up designed to block possible light cues. The researchers observed a growth response toward the tomato plants similar to that in their first experiment. Finally, to firmly establish that volatile chemicals from the host plant ...