New imaging technique tracks traffic patterns of white blood cells
...-channel videomicroscopy, researchers were able to view white blood cell subsets and their forming microdomains in the vascular system in real time. In the upcoming March issue of Nature Methods, the new research displays the migration and inner workings of white blood cells in the small veins and bone m...Trying to control pain can be a double-edged sword, say scientists
...onstantly battling pain, our research supports the view that it is better to provide a patient with the tools to cope with his or her persistent pain." The findings are welcomed by Pete Moore, lead trainer in pain management for the Expert Patients Programme Community Interest Company. "This is inte...Free drug samples influence prescribing, say one in three doctors
...d not be restricted further. "The generally held view that accepting modest incentive items, such as drug samples is appropriate and primarily of benefit to patients needs to be reconsidered, both by doctors and by policy makers," say the authors. Guidelines need to do more to challenge this view, they ...Penn researcher shows that DNA gets kinky easily at the nanoscale
..., yet it does," Nelson said. "In the conventional view of a DNA molecule, wrapping DNA into a nucleosome would be like bending a yardstick around a baseball." To study DNA on the needed short length scales, Nelson and his colleagues used a technique called high-resolution atomic force microscopy to ob...New way of tracking muscle damage from radiation
...de 60 images of the same area, including a dynamic view of what was happening in the muscles during a six-minute period following infusion of gadolinium, a contrast agent. "The rate at which the contrast agent flows in and out of a region, or whether it leaks out of the blood vessel, helps us understan...Gene linked with mental illness shapes brain region, researchers find
...ho have depression, and probably from the point of view of treatment, we should try to identify these people as early as possible and intervene before the 'hard-wiring' gets altered," Dr. German said. ...Peering into the shadow world of RNA
The popular view is that DNA and genes control everything of importance in biology. The genome rules all of life, it is thought. Increasingly, however, scientists are realizing that among the diverse forms of RNA, a kind of mirror molecule derived from DNA, many int...Genome archaeology illuminates the genetic engineering debate
...ering the normal order of genes in the genome. The view of genes being fixed in their position in the genome is largely based on studies in animal genomes. In contrast to those studies, however, the authors show that plant genomes evolved from a far more dynamic structure than previously believed. Maize...Discovery of the first resistance gene to rice yellow mottle virus
...mically useful yet susceptible to the virus with a view to optimizing their use. Standard genetic studies first found evidence that resistance was controlled by a single recessive gene. Subsequent genetic mapping identified a fragment of chromosome 4 containing the resistance gene. Data from rice genome...Hopkins scientists link immune response to 'ghost' parasites and severely congested sinuses
...nose, with a camera attached to provide a close-up view of the nasal and sinus passages. Slender surgical instruments placed alongside the endoscope allow surgeons to cut away inflamed tissue and polyps, clearing a path for the sinuses to drain normally. Lane says that if left untreated, polyps can lead...Memories: It's all in the packaging, scientists say
...onance imaging (fMRI), the scientists were able to view what happened in the brains of subjects when they experienced an event made up of multiple contextual details. They found that participants who later remembered all aspects of the experience, including the details, used a particular part of the brain...One signal elicits thousands of answers
...e provides a missing link in a global, integrative view of cellular regulation." Mann and his team improved and extended a previously developed technology, which enabled them to identify for the first time all phosphorylations of all proteins in living cells - and in their temporal dynamic. For this ap...Fast-freeze snapshot yields new picture of nerve-muscle junction
...k, developed the high-pressure freeze technique to view synapses while working in the laboratory of coauth...the neuromuscular junction and actually physically view the consequences of losing these proteins," said Richmond. The conventional technique is to use glu......operties of single-walled nanotubes (SWNTs) with a view to developing these materials as biologically compatible components of medical devices, sensors, and prosthetics. SWNTs are formed from carbon atoms by various techniques including deposition and resemble a rolled up sheet of chicken wire, but on a t...From a lowly yeast, researchers divine a clue to human disease
... Wisconsin group developed a method to get a broad view of how Sen1 works and what happens when it doesn't work properly. Normally, Sen1 acts like a molecular stop sign, telling another protein called RNA polymerase II when to stop transcribing genetic information from DNA into related threads of RNA. ...Unraveling where chimp and human brains diverge
... cell activity and energy metabolism. "If you view the brain as the body's engine, our findings suggest that the human brain fires like a 12-cylinder engine, while the chimp brain works more like a 6-cylinder engine," explained Geschwind. "It's possible that our genes adapted to allow our brains to i...Funding to tackle hospital superbugs
...of other drugs that modify host responses with the view to resolving infection and reducing inflammation in diseases such as arthritis. ...An artificial cornea is in sight, thanks to biomimetic hydrogels
...ds a lot of water. That material may promise a new view for at least 10 million people worldwide who are blind due to damaged or diseased corneas or many millions more who are nearsighted or farsighted due to misshapen corneas. Called Duoptix TM , the material can swell to a water content of 80 percen...Motorola researchers develop selective sensors based on carbon nanotubes
...h will be published in the journal Small. An early view of the article is available at the journal's web site ( www3.interscience.wiley.com/cgi-bin/jissue/10962734 7). "Our sensor is based on the novel properties of peptides and carbon nanotubes," Tao explained. "Peptides can be used to recognize and d...... observations gives scientists a uniquely detailed view of the changing physical characteristics of ocean surfaces, but long-term series of satellite measurements are required in order to detect trends. The National Oceanographic Data Center (NODC), part of the United States?National Oceanic and Atmos...