Depression model leaves mice with molecular scar
...eins that regulate the turning on-and-off of genes via a process called methylation. Methyl groups, the silencer molecules, attach themselves to the histones, turning off the gene. Notably, imipramine was unable to remove these silencer molecules, suggesting that they remained a latent source of vulnerab...Hot-spring bacteria flip a metabolic switch
...r energy and carbon dioxide into sugars and oxygen via photosynthesis. In fact, ancient cyanobacteria produced most of the oxygen that allows animals to survive on Earth. Cyanobacteria such as Synechococcus are often found in the microbial mats that carpet hot springs, where life exists at near-boiling ...Antibacterial coatings cut infection rates
...bacteria, which do the same, talking to each other via these signalling molecules until they reach sufficient density as a group on the surface. The bacteria then change their metabolism and start producing a slimy biofilm that protects them from antibiotics. Sitting under the protective biofilm, the bac...'Dating agency' boosts hunt for disease genes
... scientific infrastructure with government funding via the Medical Research Council. "The infrastructure is already up and running for handling patient samples. Now what we've done is to create a sort of scientists' dating agency and shop," explains the Director of the Network's archive, Dr Martin Yuil...Serious adverse reactions to smallpox vaccine appear to be limited
... The researchers evaluated adverse events reported via the Vaccine Adverse Event Reporting System (VAERS) and the Centers for Disease Control and Prevention. A total of 37,901 volunteers in 55 jurisdictions received at least 1 dose of smallpox vaccine. VAERS received 822 reports of adverse events follo...Carnegie Mellon U. transforms DNA microarrays with standard Internet communications tool
...ially developed to ensure that email messages sent via the Internet don't become garbled in transmission. In the standard Internet check-sum protocol, bits of information that begin as one value (0 or 1) may inadvertently flip to the opposite value as they move from one computer to the next in the form o...What can change in the brain? Electrical synapses, research shows
...r lightening-quick signals to pass between neurons via ionic current - is only beginning to be understood. Last year, the Connors lab published research showing that electrical synapses help set the brain's master circadian clock. ...Johns Hopkins flu expert calls for mandatory vaccination of health care workers
...rker or indirectly from other patients or visitors via medical staff. Previous research from Hopkins showed that annual flu shots have been almost 88 percent effective at reducing the risk of flu infection and that they reduced by one-half the number of deaths among hospital patients from the disease....... Customers typically submit sequences by email or via a form available on a company's website. The companies then construct the specified genes and mail them back a few weeks later, usually spliced into a bacterium such as Escherichia coli. New Scientist approached 16 such firms, identified by a Google ...Some good news for the world's poor
...w now that by providing them with new technologies via rice research we can lift them out of poverty," said IRRI Director General Robert S. Zeigler. The paper's lead author, Dr. Shenggen Fan, works at IRRI's sister institute, the Washington-based International Food Policy Research Institute (IFPRI). In ...WWF peeks into mysterious life of Borneo's pygmy elephants
... a collar that can send GPS locations to WWF daily via satellite. Now, for the first time, the public can track the movements of the elephants online through an interactive web map at www.worldwildlife.org/borneomap . "No one has ever studied pygmy elephants before, so everything we're learning is grou...Cancer support cells may evolve, fuel tumor growth, study shows
... cells around it. It's a back-and-forth cross-talk via which the whole entity evolves, not just a subset of cells within the cancer. It's an environment where changes in the surrounding cells are selected that will help tumor growth." Van Dyke's UNC collaborators in the new research were graduate stude...Telling axons where to go - and grow
...s the dynamics of the actin cytoskeleton primarily via phosphorylation of the actin depolymerization factors ADF/cofilin, with important consequences for cell morphology, cell motility, and the development of neuronal projections. Changes in LIMK1 concentration have an impact in neuronal growth cone act......s ?discarding parts of the proteins likely to dock via large surfaces, and zooming in on small regions of the remaining molecules that might hold motifs. Then it was up to the computer to scan the sequences for small patterns. The attempt was successful: in the fly data, for example, 26 sets of proteins ...Novel protein complex enables survival in hostile environment
...minal half of Fsr (named Fsr-N) collects electrons via F420 and the COOH-terminal half (Fsr-C) uses those...he methanogens acquired the sulfite reduction gene via horizontal transfer from that entity," Mukhopadhyay said. Rolf Thauer, professor and head of the D...Did feathered dinosaurs exist?
...ished by John Wiley & Sons, Inc. and available via Wiley InterScience ( www.interscience.wiley.com/journal/morphology ). Dinosaurs have long captured the imagination while their relationships have eluded full explanation. Innovative research and a comprehensive consideration of the old can also insp...Genetic defenders protect crops from fungal disease
... share a common purpose. However, they seem to act via different mechanisms, and PEN2 protects against a wider range of fungal pathogens. For example, Arabidopsis plants with a disabled PEN2 gene are also more susceptible to Phytopthora infestans, the fungus responsible for the notorious Irish Potato Fam...Envisat radar surveillance protects endangered prehistoric fish
...e zone. Each vessel is then sent with its position via a satellite link to the French authorities on Réunion, where they are analysed to identify legal and illegal vessels. "Authorised vessels are mandated to have an Argos satellite transmitter aboard, so they can be located and identified. Vessel pos...New view of cancer: 'Epigenetic' changes come before mutations
...rg and his colleagues propose that cancers develop via a three-step process. First, there is an epigenetic disruption of progenitor cells within an organ or tissue, altered by abnormal regulation of tumor-progenitor genes. This leads to a population of cells ready to cause new growth. The second step in...Max Planck researchers make a breakthrough in plant stem cell research
...nse Regulators", are subject to genetic regulation via the WUSCHEL gene. In particular, WUSCHEL restricts the activity of ARR7 in the apical meristem. The ARR genes in turn carry out a particularly important task in hormonal regulation: they are part of a negative feedback loop, by which the growth-induc...