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Tag: "via" at biology news

Researchers develop gene therapy to reverse pulmonary arterial hypertension

...ene therapy to deliver an inactive Survivin-mutant via a virus--known in science as a "dominant negative construct"--effectively inhibiting endogenous Survivin. The therapy reversed PAH in rats and improved their heart function and their survival, thus holding out some promising avenues of treatment for ...

Stem cells bring fast direct improvement, without differentiation, in acute renal failure

...potential late phase contributions to organ repair via differentiation of stem cells into cells that have been destroyed in ARF," the study noted. ...

Nanoscale method for investigating living systems

... of ions and which we can control from the outside via voltage." Quantum dots can be encoded with different colors making them useful as fluorescent labels for staining cells. Their resistance to photobleaching and physical size of less than 10 nanometers are making them increasingly popular in biomedic...

Taking a flying jump

...ults suggest that signals in the brain transferred via the 'giant fibre pathway', initiate a "take-off" sequence, involving stretching of the legs and depression of the wings that can move the fly in a specific direction. Previous studies did not detect directional jumping1, but observations were made i...

Aloe vera coating may prolong freshness, safety of fruits and vegetables

...Science and Technology and the European Commission via FEDER (European fund for regional development). ...

Neurologix announces positive results of gene therapy clinical trial in Parkinson's disease

...ateral (one side of the brain) infusion of AAV-GAD via a hair-thin catheter into the subthalamic nucleus ...and 12 months. These evaluations included scoring via the UPDRS, neuropsychological testing, videotaped examinations and timed motor tasks. PET scans wer...

Gene discovery sheds light on causes of rare disease, cancer

...nd in soil and water, can be transmitted to humans via undercooked and unpasteurized food, causing flu-like symptoms or gastrointestinal distress. For individuals with weakened immune systems, listeriosis can be fatal, and infections during pregnancy can lead to miscarriage, stillbirth, premature deliver...

Hide and seek: Researchers discover a new way for infectious bacteria to enter cells

...nd in soil and water, can be transmitted to humans via undercooked and unpasteurized food, causing flu-like symptoms or gastrointestinal distress. For individuals with weakened immune systems, listeriosis can be fatal, and infections during pregnancy can lead to miscarriage, stillbirth, premature deliver...

'Jumping genes' contribute to the uniqueness of individual brains

...al, but in humans a hundred or so are free to move via a "copy and paste" mechanism. Long dismissed as useless gibberish or "junk" DNA, the transposable L1 elements were thought to be intracellular parasites or leftovers from our distant evolutionary past. It has been known for a long time that L1 eleme...

Bacteria are key to 'green' plastics, drugs

...pathway metabolizes glucose and produces succinate via dissimilar chemical reactions. That means the two don't compete or interfere with one another. In fact, Bennett and San designed the paths to be complimentary, but even so, they were gratified to see how well the process worked once both paths were p...

USC researchers determine mechanism of action of chemotherapy drug

... the use of MGd leads to the death of cancer cells via disruption of critical enzymes needed for cell survival and replication. "We have increased the understanding of this drug's mechanism of action," Hacia said of the study, adding that it also may "provide support for the hypothesis that agents that ...

Gene expands malaria's invasion options

...ome P. falciparum strains invade red blood cells via protein receptors on the surface that contain a sugar known as sialic acid. If scientists treat blood cells with an enzyme to remove sialic acid, the parasite can no longer invade. Other strains - including one called W2mef - can invade using the sia...

Decisions, decisions: Male or female?

...o is active in humans and mice. When communication via the JAK/STAT pathway misfires, diseases such as cancer can result, he said. "Evolutionarily, germ cells are one of the most ancient cell types, needed by every type of animal to reproduce," Van Doren said. "Their developmental program is very simila...

New tool reveals secrets of migrating cells

... of T cells produced in the thymus and distributed via the bloodstream to the lymph nodes, whence they move into the body's tissues. Her first use of two-photon imaging three years ago surprised her and many immunologists because it showed that thymocytes or immature T cells were highly mobile, traveling...

New defibrillator signals doctor of patient's irregular heartbeat or device malfunction

...fibrillator which automatically signals the doctor via wireless satellite transmission if the patient's h... defibrillator (ICD) sends a signal to a satellite via a small transmitter that can be placed on a nightstand, worn on a belt or kept in a purse. In addit...

Bees, Brains and Addiction

...m computer modeling of the bee brain can be tested via human brain imagining studies. For example, Sejnowski said that by using functional magnetic resonance imaging, which measures blood flow to reveal which regions of the brain are active, researchers in his laboratory have discovered that our brains p...

Invitrogen Launches i-Path -- A Unique Systems Biology Platform at BIO 2005

... vitro matured oocytes and non-autologous transfer via a conventional method of nuclear transfer. "Our final goal is to use human therapeutic cloning for infertility treatment by creating artificial eggs and sperm for patients who are infertile because of absence or premature loss of eggs or sperm. We w...

Scientists succeed in cloning human embryos from eggs matured in the lab

... vitro matured oocytes and non-autologous transfer via a conventional method of nuclear transfer. "Our final goal is to use human therapeutic cloning for infertility treatment by creating artificial eggs and sperm for patients who are infertile because of absence or premature loss of eggs or sperm. We w...

Scripps research scientists solve structure of a critical innate immune system protein

...is a crucial initial step in solving its structure via x-ray crystallography, the technique that Wilson and his colleagues employ. Because glycoproteins are covered with sugars, they are heterogenous due to the multiple glycoforms that make it harder, but not impossible, to form good crystals. A number o...

Mechanism for the captation of nutrients in plants- unknown to date

...ough this mechanism is less than that incorporated via endocitosis. Thus, the experiments carried out sh...up by the fact that saccharose pick-up is produced via endocitosis is, fundamentally, to find out if the saccharose captured through endocitosis is that in...

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