Progress being made in exploring potential use of stem cells to treat heart disease
...eplacement cells for damaged heart muscle, valves, vessels and conduction cells holds great potential," says Srivastava, who is also a UCSF professor of pediatrics and the Wilma and Adeline Pirag Distinguished Professor in Pediatric Developmental Cardiology. "Although there are clearly many obstacles to over...Attacking cancer's sweet tooth is effective strategy against tumors
...ntin. Angiogenesis inhibitors would wipe out blood vessels and the oxygen supply with it, leaving the cells with no way to cope. "There is definite potential to combining these things," she said. ...U of MN uses robotic surgery techniques in cardiac cell therapy research
...been shown to improve the development of new blood vessels and to improve function of injured heart muscle. Both are in human clinical trials as well. The research is published in the current issue of the Journal of Thoracic and Cardiovascular Surgery. Once more animal studies are completed, the technique...USC researchers investigate protein that protects tumors
...er cells flourish by issuing a call for more blood vessels ?the biological equivalent of food for the tumor. ...is protein ?on its surface communicates with blood vessels nearby," Gill says. "It sends the signal for more blood vessels to grow. One key item for any cancer...Proteins spur diabetic mice models to grow blood vessels, nerves
...ow have a (growth) factor that attracts both blood vessels and nerves--that's why it's unique for diabetes," Li said. "This demonstrates that netrins are critical for development and may be important as a new therapy." Li and fellow researchers from the University of Utah and Stanford already had shown Netr...Ocean acidification threatens cold-water coral ecosystems
...tom trawling ?a commercial fishing method in which vessels drag large, heavily weighted nets across the bottom ?to be the greatest threat to cold-water corals. Now, however, a new study published in Frontiers in Ecology and the Environment suggests that human activities could be threatening cold water reefs...COX-2 inhibitors significantly reduce risk of cancer
...ell death, angiogenesis (the creation of new blood vessels to nourish growing tumors) and metastasis," says Harris, who is also a member of the OSU Comprehensive Cancer Center. Harris says his research group is only midway through analyzing data from the other parts of the study, but adds that early result...Weighting cancer drugs to make them hit tumors harder
...selectively absorbed by tumors because tumor blood vessels are more permeable or "leakier" than normal blood ... Thus, larger molecules can pass through the tumor vessels more easily. Drugs with a greater molecular weight also reduce chemotherapy's toxicity to healthy t...Man-made heart tissue improves cardiac performance
...earchers have developed a method to engineer blood vessels within the tissue of previously engineered heart m...he field of tissue engineering is to produce blood vessels within heart muscle tissue. In this study, the researchers were successful in this task. Their live...Proteins stop blood-vessel and tumor growth in mice
...rowth of cancer tumors in mice by preventing blood vessels from sprouting. The proteins are promising candida..., and that they inhibit the formation of new blood vessels in cell culture," said William Schiemann, Ph.D., Assistant Professor in the Program in Cell Biology ...Free-radical busting antioxidants might not promote healthy hearts
...etween the levels of oxidized cholesterol in blood vessels and the severity of heart disease. This might help explain the disappointing results of clinical trials with other free radical-scavenging antioxidants, such as Vitamin E, which have shown no protective effect against heart disease in humans. The pr...One fish, two fish: New MIT sensor improves fish counts
... waves off of them. With the old technique, survey vessels send high-frequency sonar beams into the ocean, where they dissipate much like the light from a flashlight shining into a darkened room. In contrast, the new system uses low-frequency sonar that can travel much greater distances and still return us...Growth factor-promoting angiogenesis expressed in tumor cells and normal neurons
...eration but instead encourages the growth of blood vessels needed to support the expanding tumor. Importantly, these findings provide definitive evidence that factors promoting tumor progression extend beyond the tumor itself and involve a complex interaction between the cancer cells and the normal cells tha...Blood flow in brain takes a twist, affecting views of Alzheimer's
...prints" of astrocytes are literally all over blood vessels in the brain: Portions of astrocytes known as "astrocytic endfeet" wrap around nearly all the blood vessels in the brain. Previously a few scientists have looked at slices of brain tissue and come up with hi...Mice with glowing hearts shed light on how hearts develop
... in the brain, in parasympathetic nerves, in blood vessels or in Purkinje fibers, which prompt the heart's ventricles to pump. The researchers have also transplanted cells from the mice with glowing hearts into normal mice to see whether the transplanted cells function normally within the host heart, which c...Leave it to salmon to leave no stone unturned
...eant to navigate in shallow waters, can find their vessels grounded. Smaller species of salmon that spawn at higher densities are capable of even more widespread tilling, according to Moore, who has for six summers worked with sockeye salmon through the UW's Alaska Salmon Program. Using counts of spawning s...Basic research leads to a novel cancer therapy
...his blocks the development of tumours. If no blood vessels are created in tumour tissue, the tumour fails to ...inhibitor, which blocks both the building of blood vessels in tumours as well as other illness-related enzymes in tumour cell signalling networks. Clinical st...Botox could help target resistant tumors for treatment
...r research, which focuses on briefly opening blood vessels that feed tumor cells in order to better deliver t...ular targeting are methods aimed at destroying the vessels that feed tumors, thereby depriving them of oxygen and nutrients. "In contrast, pro-vascular appro...Researchers develop portable 'vein finder' for faster, more accurate injections
...ubstance, so ultrasonic waves reflected from blood vessels have different characteristics than transmitted on...trasound systems to evaluate the heart, valves and vessels for general blood-flow studies. But this kind of equipment is impractical and too costly for field u......to Ménard, since they need to travel through blood vessels to get to the liver. However, many of the parasit...ed by the mosquito bites were drained by lymphatic vessels and ended up in lymph nodes close to the site of the bite. Their journey seemed to stop there, as th...