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Tag: "vessels" at biology news

New bacterium discovered -- related to cause of trench fever

...ause extremely painful lesions and tumors of blood vessels on the skin of immunocompromised patients. But when I saw this patient, this type of infection had never been seen at UCSF, and the bacterium causing the infection was unknown.” Koehler’s group went on to discover that two different Bartonella s...

Studies to find better ways to preserve human eggs, ovarian tissue under way

...eorgia Institute of Technology to regenerate blood vessels and pancreatic substitutes, noting studies published in Tissue Engineering and Cell Transplantation. “Regenerative medicine will help supplement the shortage of organs in the future, and we need technology to preserve those we make.” ...

Migration alert -- How tumor cells home in on the lymphatic system

...This means that tumor cells “know” which lymphatic vessels will be more effective routes for dissemination,” she explains. “Therapeutically, it indicates that a drug target for lymph node metastases could be blocking the signaling molecule or its receptor on the tumor cell.”...

University of Pittsburgh School of Medicine researchers develop 'off-the-shelf' vascular grafts

...ine investigators have engineered artificial blood vessels from muscle-derived stem cells (MDSCs) and a biode... there is a critical need for new sources of blood vessels for vascular grafts. The saphenous vein taken from a patient’s leg continues to be the most commonl...

3-D ultrasound scanner provides in-depth view of the brain

... use of dyes to enhance ultrasound images of blood vessels in the brain. The new advance is the latest in a series of developments Smith's team has made since developing the first 3-D ultrasound scanner in 1987 for imaging the heart from outside the body. "Wherever there is a commercial 2-D niche now,...

Statin treatment improves spatial memory in mouse models of Alzheimer's

...ide, a substance that causes dilation of the blood vessels in the brain, which eventually will increase blood flow and improve circulation to the memory region of the brain. These findings suggest that increases in brain nNos levels may play an important role in statin-induced improvement of spatial referenc...

Mice with a migraine show signs of brain damage

...ds for oxygen are suddenly so great that the blood vessels in the brain can’t keep up,?said Nedergaard. “It’s....? Brain tissue closest to the oxygen-rich blood vessels soaks up the oxygen as fast as they can, leaving tissues further away with a diminished supply. It’s...

Catching cancer's spread by watching hemoglobin

...high-resolution, three-dimensional images of blood vessels by taking advantage of the natural multiple-photon...uke University, should provide 3-D images of blood vessels in relatively deep tissue (up to 1 mm, much better than conventional microscopes) with a resolution ...

How to steer a moving cell

...imary tumor, crawl through tissues and enter blood vessels ?spreading the cancer throughout the body. Richard Klemke, Ph.D., professor of pathology at UCSD School of Medicine and the Moores Cancer Center, and his colleagues set out to better understand the complexity of signaling mechanisms within the cel...

Students invent protective pouch to enhance cell therapy

...ts, similar to the ones used to keep clogged blood vessels open. Once the stents are in place, microcapsules ... device causes no pressure drop in the model blood vessels and that the microcapsules can easily be injected and withdrawn. Link said he and his team member...

Studies force new view on biology of flavonoids

...de synthase, which has the effect of keeping blood vessels healthy and relaxed, preventing inflammation, and lowering blood pressure ?all key goals in prevention of heart disease. Both of these protective mechanisms could be long-lasting compared to antioxidants, which are more readily used up during thei...

Cure for cancer one step closer

...d the world, and two vapour phase nitrogen storage vessels (-196ºC) and two -80ºC freezers which have the capacity to house in excess of 164,000 tissue and blood samples. The small sections of tissue collected from patients will be stored in cryogenic vials which will help preserve the tissue's proteins a...

Nanotextured implant materials: blending in, not fighting back

...to killing off bad cells." Normal healthy blood vessels have a thin lining of specialized cells called the endothelium, surrounded by a thicker layer of smooth muscle cells that make up the arterial wall. The proteins collagen and elastin make up much of this lining and create a texture of fine nanoscale ...

Researchers identify ovarian cancer biomarkers

...ve identified markers unique to the cells of blood vessels running through ovarian tumors. The finding, while...rs that were present in large amounts in the blood vessels of cancer tissue but not in the vessels of normal tissues. The researchers went on to study in deta...

Genes set scene for metastasis

...that work together to remodel the network of blood vessels at the site of the primary tumor. These genes were also found to promote the spread of breast cancer to the lungs. The study, conducted in mice and reported in this week's Nature, helps to explain how cancer metastasis can occur and highlights target...

A genetic 'gang of 4' drives spread of breast cancer

...e into the bloodstream and penetrate through blood vessels into lung tissues. Although shutting off these ge...enes greatly reduced growth of the tangle of blood vessels typically seen in tumors. Further experiments revealed that the tumor blood vessels that did form al...

Molecular differences between early and advanced melanomas could provide new drug targets

... of angiogenesis Ð the growth of microscopic blood vessels that nourish cancerous tumors and lead to unregulated cell growth. When melanoma cells overexpressing Akt were introduced into immunocompromised (nude) mice, the mice developed aggressive tumors that expressed high levels of VEGF, whereas a control ...

Blame the brain for high blood pressure

...olecule-1), which is located in the walls of blood vessels in the brain. JAM-1 traps white blood cells c... to understand the type of inflammation within the vessels in the brain, so that we know what drug to use, and how to target them. JAM-1 could provide us with ...

UW launches study testing adult stem cells for heart damage repair

... occurs when the coronary arteries and the smaller vessels that supply oxygen-rich blood to the heart muscle ...l blood clots downstream, blocking the small blood vessels in the heart. These blockages can result in a series of mini-heart attacks that, while they may b...

Twin studies reveal genetic components leading to cardiac and kidney disease

..., such as heart attack or stroke. "When blood vessels stop contracting and relaxing properly, it is the first indication of vascular dysfunction," said O’Connor The endothelium secretes several hormones that are markers of how well it is functioning. Release of one of these markers, called endotheli...

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