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Tag: "versions" at biology news

Cellular message movement captured on video

...stasis, and other disease processes. Tumor-causing versions of signaling molecules may attach to paxillin and disturb the normal adhesion and growth factor signaling steps required for controlled proliferation and cell growth. For example, human papilloma virus, which can cause cervical cancer, makes a protei...

First confirmed common genetic risk factors for breast cancer

...sociated with breast cancer susceptibility. Normal versions of these genes help prevent cancer from occurring in the first place, by helping cells to repair DNA breaks and other abnormalities that can result from chance or exposure to an environmental toxin, such as excessive UV sunlight. However, BRCA-1, BRC...

Survival of the rarest: Fruit flies shed light on the evolution of behavior

...y in populations of fruit flies with two different versions of the foraging gene. This gene is of particular i...of the virus. In this case, flies carry one of two versions of the foraging gene (either the "rover" or "sitter" type). Rover larvae move around more than sitte...

Dinosaur hearing, listening to muscle noise, quieter cubicles

...ity meeting and will include numerous lay-language versions of selected meeting papers. These papers will enable you to cover the meeting, even if you can't leave your desk. NOTEWORTHY SALT LAKE CITY MEETING EVENTS For those at the meeting, there will be noteworthy sessions including an evening tutori...

Gene found for rare disorder may reveal new pathway in mental retardation

...ients with the SMCIA and SMC3 mutations had milder versions of the distinctive facial features found in classical CdLS, such as thin eyebrows that join together, long eyelashes, thin lips and excessive body hair. "In many of these patients, an experienced clinician might recognize their more subtle facial...

Individual differences in a clock gene predict decline of performance during sleep deprivation

...he human population, encoding either long or short versions of the corresponding protein. Each individual will possess two copies of the gene, either of which might be the long or short form. Previous work had indicated that the different forms of the gene appear to influence characteristic morning and evenin...

Bacterial walls come tumbling down

...me function should help scientists design modified versions that are more suitable for use in people. Understanding the structure of this enzyme should also speed up screening and design of new antibiotics, which are in constant demand as microbes continually evolve new ways to evade the drugs that researc...

RNA enzyme structure offers a glimpse into the origins of life

...difficult, and Robertson tried dozens of different versions of the ribozyme under different conditions before he succeeded. Using x-ray crystallography--which involves shining a beam of x-rays through the crystals and analyzing the resulting diffraction patterns--Robertson and Scott were then able to determin...

Gene therapy for blindness clears hurdle in mice

...ene is essential for healthy eyesight, but mutated versions of it are passed from generation to generation in ...n experiments to create a therapy in which healthy versions of the gene can be introduced into the eye using an apparently harmless virus to deliver the genetic...

Scientists find new genetic clue to cause of Alzheimer's disease

...ealth (NIH). The researchers suggest that faulty versions of the SORL1 gene contribute to formation of amylo... research is needed to determine the how different versions of the SORL1 gene influence production of the harmful protein fragments. ...

Motor protein plays key role in connecting neurons

...ons during development," says Dr. Xiong. Different versions of the myosin family proteins are critical to essentially every cell including muscle cells and those that turnover and divide rapidly, such as skin and intestinal cells, and eggs or oocytes. The rapidly moving protein is easily degraded an...

Killing the messenger RNA -- But which one?

... "What we found was that, in certain cases, edited versions of these microRNAs are being produced that differ from the unedited versions by only a single nucleotide change," says Kazuko Nishikura, Ph.D., a professor in the Gene Expressio...

Chromosomal microarray analysis proves accurate

...romosomal testing did not. This study involved two versions of the test, and the newer version was more successful in identifying chromosomal abnormalities. The targeted microarray analysis used here is essentially a gene chip method of assessing the makeup of chromosomes in a particular part of the human ...

Virginia Tech's System X supercomputer provides super tool for simulation of cell division

...h computer science team created massively parallel versions of a deterministic global search algorithm, DIRECT, and a deterministic local search algorithm, MADS, to do the twiddling, and then combined the results. "A deterministic global search algorithm systematically explores the parameter space, finding go...

Early-stage immune system control of HIV may depend on inherited factors

...f infection appears to depend on both the specific versions of key immune-system molecules called HLA Class I ... the immune system in early infection and that the versions of HLA Class I previously associated with slower HIV-1 disease progression also contribute more to t...

Tarantula venom and chili peppers target same pain sensor

...apsaicin receptor. They also showed that synthetic versions of the venom peptides activated the receptor. In studies with mice, they found that normal animals flinched when their paws were exposed to the peptides, which they call vanillotoxins. Mice genetically engineered to lack capsaicin receptors did not r...

Study uncovers mutation responsible for Noonan Syndrome

...tructures of SOS1, the scientists made recombinant versions of the mutants and expressed them in mammalian cells, where it was discovered that they promoted excessive activation of RAS and its downstream target, MAP kinase, the same pathway activated by PTPN11 mutations. "These results are the first exampl...

When the label says 'low fat,' calories can pile up, study says

... to 50 percent more calories when they eat low-fat versions of snack foods than when they eat the regular versions, according to a new Cornell study. Further, a companion study finds, when food labels show serving sizes on such packaged low-fat snacks as granola or chocolates, normal-weight people tend not t...

Does missing gene point to nocturnal existence for early mammals?

...e animals like birds, fish and amphibians have two versions of this photoreceptor, mammals, including humans, only have one. The findings ?published in the Public Library of Science journal PLoS Biology ?reveal how our experience of the light environment may be impoverished compared to other vertebrates an...

Stanford discovery may help predict when toxoplasma can be deadly

...es in their hosts. "We think that the different versions of Toxoplasma strains evolved for optimal interaction with different hosts," said Boothroyd, noting that the wrong pairing of parasite and host can have dire consequences. "If a given strain gets into the 'wrong' host, the result is a system out ...

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