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Tag: "verified" at biology news

DNA Molecules Used To Assemble Nanoparticles

...sing cell sorters, 3-D microscopes and other tools verified that these dendrimers hit their targets, were admitted into the cells and gave off their signaling light. The self-assembled dendrimer clusters were shown to be well formed and functional. "This is the proof-of-concept experiment," Choi said. But no...

Another Look Finds Promising Proteomics Test is Not Biologically Plausible

...s laboratories so that results from one lab can be verified by others. "We are moving in that direction,?he adds. “The technology being used to develop a variety of proteomic diagnostic tests is getting better and we are getting more reproducible results.? Researchers worldwide are excited about the notion o...

New species from old data

...s laboratories so that results from one lab can be verified by others. "We are moving in that direction,?he adds. “The technology being used to develop a variety of proteomic diagnostic tests is getting better and we are getting more reproducible results.? Researchers worldwide are excited about the notion o...

Cracking the olfactory code in bees

...s laboratories so that results from one lab can be verified by others. "We are moving in that direction,?he adds. “The technology being used to develop a variety of proteomic diagnostic tests is getting better and we are getting more reproducible results.? Researchers worldwide are excited about the notion o...

Signaling protein builds bigger, better bones in mice

...s laboratories so that results from one lab can be verified by others. "We are moving in that direction,?he adds. “The technology being used to develop a variety of proteomic diagnostic tests is getting better and we are getting more reproducible results.? Researchers worldwide are excited about the notion o...

Gene variations explain drug dose required to control seizures

...er of the IGSP. If the genes' predictive value is verified in clinical trials, such a "pharmacogenetic" approach might make it possible to safely reduce the time required for patients with epilepsy and their physicians to reach an effective dose of the medications that control seizures, said David Goldstein,...

Discovery Promises Simpler Therapy for Sickle Cell Disease

...e genetic defect, Stamler said. "This finding, if verified in clinical trials, could change physicians' approach to sickle cell disease," Stamler said. "Current efforts for managing the disease completely miss the role that red blood cell-derived nitric oxide plays. The disease might therefore be treated by ...

Measuring Enzymes At End Of Cancer Pathway Predicts Outcome Of Tarceva, Taxol

...rrow Transplantation. If results of this study are verified and validated, "a CDK2 test would provide the best marker yet for effective use of Tarceva," he says. The only experimental predictive test currently available is whether lung cancer cells have a mutation in their epidermal growth factor receptor (EG...

Supercomputers to focus brains on AIDS dilemma

...'s very exciting that scientists at Merck have now verified all of this experimentally." A paper by Daria Hazuda, a leader of Merck's drug discovery group, and her colleagues at Merck and the Instituto Ricerche di Biologia Moleculaire in Rome published in the August 3, 2004 Proceedings of the National Academ...

Gov't Creates Gene Database of Normal Human Tissues

...e than 42,000 detectors built into two chips using verified cDNA libraries upon which many other researchers currently rely. Analyzing the organ tissue with this tool allowed Khan and his team to identify 18,927 genes that constitute their database. "We found that each organ had a unique expression level prof...

A novel method to measure circadian cycles

... rhythms is an anecdotal as well as experimentally verified fact. But, until now, to systematically study circadian differences (and thereby hope to rout out the underlying genetic causes), scientists have had to rely on prolonged behavioural observation. To screen for and identify circadian rhythm variation...

Scientists create digital bacteria to forge advances in biomedical research

...physical Dynamics. Emonet and his colleagues have verified the accuracy of AgentCell in biological experiments. AgentCell now enables scientists rapidly to run test experiments on the computer, saving them valuable time in the laboratory later. Emonet is the lead author of a paper announcing the development...

New law for resolution allows unprecedented sharpness in fluorescence microscopy

...olution limit in fluorescence microscopy, and then verified it in experiments. Unlike in the light microscopes conceivable so far, in a STED microscope, the relevant focal fluorescence spot can, in principle, be reduced in size to the size of a molecule (2-5 nm). This is due to the fact that the spot size is ...

Rutgers researchers scientifically link dancing ability to mate quality

...yday life, however, has not always been rigorously verified by science. Now, a study by scientists at Rutgers, The State University of New Jersey, for the first time links dancing ability to established measures of mate quality in humans. Reporting in Thursday's edition of the British science journal Nature,...

Many needles, many haystacks

...d bind to the fly protein translin. The scientists verified that this happened, then they made subtle changes in the sequence. When these changes stopped the molecules binding, they knew they had a new linear motif. Now the lab will expand the method; Russell predicts that hundreds of linear motifs remain to...

Avian flu transmission to humans may be higher than thought

...med human cases of HPAI (with 38 deaths) and 1,838 verified outbreaks in poultry in July 2005. In this study, the researchers found "a total of 8,149 individuals (17.9 percent) reported flu-like illness, 38,373 persons (84.4 percent) lived in households keeping poultry, and 11,755 (25.9 percent) resided in h...

Dogs keep dying: Many owners unaware of toxic dog food

...uated several times." Cornell veterinarians have verified diagnostic tests enabling detection of seriously poisoned dogs. Aflatoxin curtails the production of cholesterol and many proteins that profoundly affect blood clotting. A minimum screening profile should assess the liver enzyme ALT to detect damage ...

Inflammation and drugs to control this activity studied in a variety of tumors sites

... humans," she said. Her team's results need to be verified in other populations, she said. "While our results are statistically suggestive that there is an association between these variations in the gene and colorectal adenomas, there needs to be biological follow-up so we know the functional relevance of t...

MatBase -- A new transcription factor knowledge base released by Genomatix

...27.000 known TF ?gene interactions, experimentally verified complexes with other TFs (promoter modules), and weight matrix descriptions for the DNA binding sites of TFs.In contrast to other available TF databases, each entry in MatBase is thoroughly tested for quality and usability for functional analysis of ...

High-throughput oncogene mutation detection in human cancers by mass spectrometry-based genotyping

... 15 different cancer types, and then independently verified over half of the mutations they identified using traditional DNA sequencing or other methods. They found that over 92 percent of mutations identified by the mass spectrometry method were validated in this manner, and believe that much of the differen...

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