Artificial cornea offers better results for infants, some blind patients
... source for transplants, such tissue can trigger a variety of problems, including rejection by the immune system as well as difficulties such as scarring from infections or out-of-control growth of blood vessels. For years doctors have worked to develop an artificial cornea, known as a keratoprosthesis or a ...Taking 'chips' to the next level of gene hunting
...rcent of the genome long believed to be "junk." A variety of DNA microarray technology, one of the two new chips, called the TIP-chip (transposable element insertion point) can locate in the genome where so-called jumping genes have landed and disrupted normal gene function. This chip is described online th...Embryonic patterning makes the feathers fly
...ltured embryonic chicken skin model and targeted a variety of potential downstream signaling pathways with specific inhibitors. They got their biggest hits with the so-called mitogen-activated protein kinase, or MAPK, pathway. Manipulating the MAPK pathway produced a wide repertoire of feather patterning, fr...... genes. Yet few know anything about epigenetics, a variety of methods that our cells have evolved to transmit heritable changes without changing DNA. Among other things, epigenetics is crucial to differentiation, the process which makes one cell from another, and thus is at the heart of the mystery of stem...Seals protect brain, conserve oxygen by turning off shivering response on icy dives
...cause they are problems that affect people under a variety of circumstances. Doctors often are called upon to treat people who have suffered accidental hypothermia, for example, as a result of falling into the ocean or becoming lost during the winter. In addition, several hundred thousand people die or are i...... Alpha9alpha10 nicotinic receptors are found in a variety of body tissues, including white blood cells and the dorsal root ganglia ?a group of nerve cells near the spine and involved in pain transmission. The new study showed alpha9alpha10 nicotinic receptors provide a previously unknown route to pain re...Rising ocean temperatures, pollution have oysters in hot water
... grounds." The oyster beds are also important to a variety of marine life that serves as food for larger fish. It was within this context that the North Carolina team did their study. Warm water increases energy demand The researchers divided oysters into three groups. One group was acclimated to wat...Plant-derived molecules, genetic manipulation point to future chemoprevention methods
...rly interactions can be manipulated to stave off a variety of cancers. The latest studies with new and promising chemopreventive agents were presented at the American Association for Cancer Research's Frontiers in Cancer Prevention Research meeting today. Trterpenoids and the rexinoid LG100268 prevent lung...Most important actors in the growth process of neurons identified
... new finding can lead to better understanding of a variety of nerve diseases. A complex network A human being has approximately 100 billion neurons, the body's information and signal processors. The great majority of them are found in the central nervous system. The brain contains complex networks of neuron...Genetic study of Neanderthal DNA reveals early split between humans and Neanderthals
...e specimens. However, the scientists performed a variety of studies to confirm that the vast majority of the human-like sequence in the library was indeed Neanderthal and not just contamination from human bone collectors and laboratory workers. The researchers then verified the authenticity of the Neande...Researchers make nanosheets that mimic protein formation
...eir ability to self-organize, it will help us in a variety of practical applications from light-harvesting na...ins comprise the outermost cell envelope of a wide variety of bacteria and other single-celled, prokaryotic organisms called archaea, and they are able to form...High-throughput oncogene mutation detection in human cancers by mass spectrometry-based genotyping
... to detect a spectrum of known gene mutations in a variety of cancer genes that they say is both sensitive and cost-effective. They say that if validated, this method of genotyping might ultimately be used in "real time" to match patients to available targeted therapies. Results were presented at the first ...Engineer ramps up protein production, develops versatile viral spheres
...stems to mass-produce designer proteins for a wide variety of medical uses. At the annual meeting of the American Chemical Society (ACS) Sept. 13 in San Francisco, Stanford engineering Professor James Swartz will discuss advances in such "cell-free" protein synthesis, including production of versatile, nanos...Protein 'fingerprint' in spinal fluid could spot Alzheimer's disease
...lecular engineering at Cornell. Researchers at a variety of centers have long sought biomarkers in blood or cerebrospinal fluid that identify the presence of Alzheimer's pathology and distinguish it from other conditions that cause dementia. "Some of these studies have met with limited success, but mos...Edge density key to controlling gypsy moth spread
...ame plan of containment might aid in controlling a variety of pests. ...Mass vaccination unnecessary in the event of a large bioterrorist US smallpox attack
...th and Human Services Tommy Thompson to evaluate a variety of intervention strategies to determine whether the United States could contain a large-scale smallpox bioterrorist attack and, if so, how. Specifically, the researchers were charged with determining whether surveillance and containment ?isolation ...Beyond the book: Software automates access to brain atlases
... revised NeuARt II interface indexes the data in a variety of ways, including spatial maps and alphanumeric information, coming off a single interface. It includes all the information in the printed volumes, in a much more accessible form. It does so without violating copyright, Burns said. Publishers of t...Researchers create genetically matched embryonic stem cells for transplantation
...cted embryonic stem cells into MHC-matched mice, a variety of specialized tissues formed, with no rejection and no need to suppress the recipients' immune system. Daley's laboratory at Children's Hospital Boston is now trying to replicate its results with human eggs. As Daley noted, there are several pot...Twenty Years of Malaria Research: Outcomes and Perspectives
...owned experts and featuring talks and debates on a variety of topics related to malaria, from epidemiology to therapeutics and from immunity to socio-economics. As the Shoklo Malaria Research Unit (SMRU) in Mae Sot, Thailand, which borders Burma, celebrates its twentieth anniversary, its Director, Professo......said that the functional classification embraced a variety of industrially important genera, including Lactococcus, Enterococcus, Oenococcus, Pediococcus, Streptococcus, Leuconostoc, and Lactobacillus species. "The sequence of these diverse species offered a window into the sugar metabolism and energy conver...