Making Sure Sacred Sheep Don't Become Extinct
...ed by breeders or researchers to introduce genetic variation into existing Churro populations. At one time, there were 2 million of these sheep. In 1977, when conservation efforts started, there were fewer than 500. Now the estimates are around 1,500.—By David Elstein, Agricultural Research Service Informatio...Tamoxifen-like drug suggests new ways to selectively block estrogen
... 40 to 50 in progress." GW5638 was developed as a variation on tamoxifen in the early 1990s by co-author Tim Willson and colleagues at what was then Glaxo Wellcome, hence the name GW5638. McDonnell, at Duke, recognized its potential and demonstrated efficacy in animal models of tamoxifen-resistant breast canc...Unique library of plant genes germinates, takes root at UNC
...sts trying to understand the genes contributing to variation in traits of economic importance in crops," Vision said. ...Excess liver gene protects against high-fat diet
...chers reported. The findings suggest that natural variation among individuals in the quantity of the liver receptors might lead to differences among them in their susceptibility to high cholesterol and heart disease in a manner dependent on diet. Furthermore, drugs that modulate LXRa activity may have potenti...Certain fish have a special mating preference
...ies, inferring possible modes of speciation. Since variation in predator regime exists between as well as within species, we can test specific theoretical predictions regarding genital evolution to evaluate what processes might have caused the patterns." Langerhans also plans to examine whether other species ...IMF Launches World’s First DNA Database for Myeloma Patients
...ies, inferring possible modes of speciation. Since variation in predator regime exists between as well as within species, we can test specific theoretical predictions regarding genital evolution to evaluate what processes might have caused the patterns." Langerhans also plans to examine whether other species ...Depression gene may weaken mood-regulating circuit
...ed on possible functional consequences of a slight variation in its DNA sequence across individuals. Everyone inherits two copies of the gene, one from each parent, which comes in two common versions: short and long. The short version makes less protein, resulting in less recycling, increased levels of seroton...Researchers extend mouse lifespan by protecting against free radicals
...o on. The researchers studied mice with a genetic variation that made them produce more human catalase, the enzyme that breaks down hydrogen peroxide. They targeted delivery of the catalase to different areas of the cell: the cytoplasm, where catalase normally goes to decompose hydrogen peroxide; the nucleus,...New tool reveals secrets of migrating cells
...brary Of Science-Biology. Two-photon imaging is a variation on the standard technique of labeling cells with fluorescent dye and then hitting them with a laser that makes the dye glow and the cells light up. A certain energy or color of laser light is needed to make the dye, in this case green fluorescent pro...Fluorescing lab worms signal longer life spans
...The CU-Boulder researchers attribute the life span variation observed in the genetically identical worms in the...e reporter protein could predict up to a four-fold variation in the life expectancy of a worm. In a typical experiment, the brightest worms had life expectancies...Variation in HIV's ability to disable host defenses contributes to rapid evolution
...ause HIV to mutate, and might even promote further variation in the virus within patients. "This work elucidate...V, Murray D, Huang Y, Ho DD, et al. (2005) Natural variation in Vif function can differentially impact APOBEC3G/3F neutralization: A potential role in HIV-1 dive...New mitochondrial DNA gene chip may be early cancer diagnosis tool
...ancer indicators against the background of natural variation in mtDNA. The NIST Cancer Biomarker Validation and Reference Laboratory assesses cost, efficiency and reliability of potential diagnostic techniques using biomarkers before further clinical evaluation in other laboratories of the EDRN. The lab found...Looks matter to female barn swallows
...usly rule out biases such as age, size and initial variation in signals of male quality, like coloration, and to demonstrate that mate-selection decisions are continual and dynamic. The results of the study have implications for the evolution and upkeep of showy ornamental traits -- such as a peacock's tail or...NIH renews network focused on how genes influence drug responses
...rogram to examine the genetic basis for individual variation in response to medications for treating tobacco de... NCI for a multidisciplinary team to study genetic variation in the molecular pathways that regulate anticancer drug responses. (Howard L. McLeod, Pharm.D., Wash...Carnegie Mellon University research reveals how cells process large genes
...s from mRNAs, generating structural and functional variation among the gene products." ...Reversal of role for a viral protein associated with the development of lymphoma
...s from mRNAs, generating structural and functional variation among the gene products." ...Cultural norms not unique to human societies
...how some cultural behaviors, the level of cultural variation shown by chimpanzees is exceeded only by humans. The study, conducted at the Yerkes National Primate Research Center of Emory University by a collaborative team of scientists from the United States and the United Kingdom, is published in the current ...Survival of heart patients on beta-blockers varies greatly with genetic variation
...he beta-2 gene commonly has two points of sequence variation within the human population--for most of the population, the gene's coding sequence will be identical from person to person at all other points. Thirty-nine percent of the population possess a set of beta-2 genes with a C base at position 79, and 16 ......one knows morning people and late-night owls. The variation in individual circadian rhythms is an anecdotal as well as experimentally verified fact. But, until now, to systematically study circadian differences (and thereby hope to rout out the underlying genetic causes), scientists have had to rely on prolon...