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Tag: "variant" at biology news

Research updates 65-year-old genetic discovery

...tistician and geneticist, concluded that this gene variant was the same in humans and chimpanzees and existed...n't have the same change in the middle of the gene variant as humans, but rather have a change at the start." Both changes in the sequences cause this bitter t...

Variation in bitter-taste receptor gene increases risk for alcoholism

...ol of Medicine in St. Louis, has found that a gene variant for a bitter-taste receptor on the tongue is assoc... In cell culture experiments, Goate found that the variant receptor produced by this gene was less responsive to bitter compounds. "The more common variant is...

Face perception is modulated by sexual orientation

...ngs indicated that invariant (facial identity) and variant (facial expression) features are similarly processed in the brain, independent of the gender of the individual who is viewed or the sexual orientation of the viewer. The researchers found that, consistent with their hypothesis, the gender of a viewe...

Evolution follows few of the possible paths to antibiotic resistance

...penicillin and cefotaxime. Analyzing how well each variant protected host Escherichia coli cells against trea...n contrast, most mutational paths of the enzymatic variant we examined fail to continuously increase resistance. Importantly, this is not a reflection of the f...

Gene variation increases SIDS risk in African Americans

...o clear idea how it increased risk since the Y1103 variant did not affect channel operation under normal conditions." Cellular activity, particularly that of nerve and muscle cells, is controlled by the flow of ions like sodium and potassium. A change in an ion channel, if it disrupts ion flow, can alter...

A large step forward in the fight against African sleeping sickness

.... For some time now, scientists have known that a variant of ApoL-1 is not neutralized by Trypanosoma brucei rhodesiense. This truncated ApoL-1 variant can help to overcome the parasite that infects our body, but only when it is present in very high co...

New weapon in battle against osteoporosis

...ar biologist. Many patients carry a particular variant of the CB2 gene But how far can these results be...oved a complete success: "We found that a specific variant of the CB2 gene occurs more frequently among the patients than among the healthy control group," say...

Inflammation and drugs to control this activity studied in a variety of tumors sites

... subgroup of individuals who had two copies of one variant showed a statistically significant reduction of nearly 70 percent in the risk for developing adenomas. Among the other individuals who did not have this genotype, regular use of ibuprofen had little effect on risk of colorectal adenomas. "Our data ...

New human retrovirus originated in mice

...ate cancer is tenuous at best. "First, the genetic variant we studied occurs in familial clusters that constitute only a very small sliver of prostate cancers," he said. "And secondly, there are many reasons to believe that the virus might not relate to prostate cancer." For example, he pointed out, analys...

Viral genetic differences are possible key to HIV dementia

...ins. "If we identify the quintessential neurotoxic variant of HIV, could we use that as a predictor of HIV dementia?" He says that such knowledge could also help care providers make "guided therapeutic decisions ?for example, the detection of particular viral genotypes may lead physicians to select for anti...

H5N1 vaccine could be basis for life-saving stockpile

...ey developed a few years ago against one antigenic variant of the avian influenza virus H5N1 may protect huma...accine could be developed specifically against the variant causing the outbreak, the researchers said. An antigen is a molecule that stimulates production of a...

Scientists to employ Arctic ice and polar bears to protect diversity of world's crops

...ey developed a few years ago against one antigenic variant of the avian influenza virus H5N1 may protect huma...accine could be developed specifically against the variant causing the outbreak, the researchers said. An antigen is a molecule that stimulates production of a...

Ready, set, mutate?and may the best microbe win

... about 700 of those were capable of creating a new variant of the target gene. In all, the researchers identified 343 unique strains, each of which contained one of just six variants of the critical gene. The first of the six, dubbed Q199R, arose almost immediately, and was the dominant strain through the 5...

Chimpanzee study reveals genome variation hotspots

...irst step in studying the evolution of copy number variant regions and their downstream implications for disease and phenotypic variation," Perry says. In the study, researchers looked at the structural genomic variation in DNA samples of 20 wild-born male chimpanzees. "We identified 355 copy number varian...

DNA to the defense

...r surface. These proteins are encoded by VSGs, or variant surface glycoprotein genes. While the immune system attacks most of the parasites in a given host, some trypanosomes rapidly evolve and express new variants of VSG, thereby allowing the parasite to persist and spread through a population. In the ...

Prion find points way to test for human 'mad cow' disease

... transmission of the malformed proteins that cause variant Creutzfeldt-Jakob disease (vCJD) via blood transfu...al biochemical test that will determine how common variant CJD is, and keep contaminated blood and organs from spreading it further." Creating such a test is ...

Large-scale genomics project will hunt genes behind common childhood diseases

... the five percent of people with a particular gene variant for a disease, but also the larger percentage who suffer the disease without having that variant." To accomplish the large-scale genotyping analysis, the Center for Applied Genomics at Children's Hospital will use the BeadLab, a highly automated la...

Control measures fail to stop spread of new H5N1 virus

A new variant of the bird flu virus H5N1 emerged in late 2005 an...also warned that it is possible that this new H5N1 variant will spread further through Asia and into Europe, as it evolves to form other sublineages that vary ...

Tamed 11,400 years ago, figs were likely first domesticated crop

...s. "In this intentional act of planting a specific variant of fig tree, we can see the beginnings of agriculture. This edible fig would not have survived if not for human intervention." Figs are very easily propagated: A piece of stem stuck in the ground will sprout roots and grow into a plant. No grafting ...

St. Jude test of bird flu vaccine proves successful

...and public health officials fear that such an H5N1 variant would trigger a human pandemic (worldwide epidemic...ne system to track and attack such an emerging new variant without missing a beat," Webby said. "We wouldn't have to wait to start developing a vaccine against...

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