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Tag: "vaccine" at biology news

CHAVI announces international search for genes affecting HIV response

...the infection on their own -- and try to produce a vaccine to mimic those responses. "We intend to use natur...oint the way toward the most promising avenues for vaccine development," said David Goldstein, Ph.D., director of the Center for Population Genomics and Pharma...

How HIV 'exhausts' killer T cells

...ersons immunized with vaccinia virus, a live virus vaccine against smallpox that is effectively cleared by the immune system. According to Walker, those findings indicate that activation of the PD-1 pathway occurs during the immune system's general response to viral infection. In test tube studies, the...

Bird flu study highlights need to vaccinate flocks effectively

...etection of bird flu, irrespective of the level of vaccine protection in a flock. Dr Nick Savill, of the University of Edinburgh's Centre for Infectious Diseases, said: "Vaccination reduces the chance of birds becoming infected and reduces the amount of virus they shed and the time over which they shed it...

The molecular mechanism of a diabetes vaccine revealed

...partment has revealed the molecular mechanism of a vaccine for Type 1 diabetes. The new findings should help ... years ago, Prof. Cohen and colleagues developed a vaccine that arrests the progression of Type 1 diabetes in laboratory animals. They had discovered that a pa...

Virus has 'catastrophic' affect on red squirrels, research shows

...de Act. Researchers say that in the absence of a vaccine for the disease the only effective way of stopping the spread is to target grey squirrel control at the narrow entry points and corridors to England's 16 designated red squirrel refuges by killing the small numbers of greys that may come in. Squir...

High-dose flu vaccines appear to safely boost immunity in elderly

...xamined 30 minutes, two days and 28 days after the vaccine and were contacted six months later to inquire abo...verage, individuals who received higher dosages of vaccine had higher concentrations of antibodies against the flu virus in their blood one month later. In ad...

Scientists aim to thwart use of flu as bioweapon

...y more. "But with bird flu on the horizon and the vaccine shortages that have occurred in recent years, it's become a hotbed of research interest. Besides, flu is responsible for 35,000 deaths and 200,000 hospitalizations in the United States alone. It's a serious health problem," Topham added. ...

Radiation-killed bacteria vaccine induces broad immune response in mice

... San Diego, School of Medicine demonstrated that a vaccine made from irradiated Listeria monocytogenes bacteria, unlike a vaccine made from heat-killed bacteria, provides protection against challenge with live Listeria. The irradi...

Researchers add crucial information on how the body's T cells react to parasitic diseases

...ite--making this set of proteins a poor choice for vaccine development, Tarleton said. The importance of the new research, however, isn't in specifically what happens in T. cruzi and Chagas Disease. Rather, it is a new understanding of how T cells react to infection in all parasitic diseases, including ma...

Mice lacking key immune component still control chronic viral infections

...iral proteins for CD8 T cells to recognize. If so, vaccine developers may need to revise their approach in order to create vaccines that trigger the most potent antiviral immune responses. "The ultimate relevance of these backup systems to human disease isn't known yet, but it's worth noting that we never ...

Silence of the amoebae

...ility of these silenced amoebae to serve as a live vaccine by evoking an intestinal immune response. If successful, it may put an end to amoebic diseases that claim the lives of thousands yearly and afflict millions more....

Heat-shock protein vaccine reduces alveolar bone loss

Heat-shock protein (HSP) can be utilized as a vaccine to cross-protect against multiple pathogenic speci...omonas gingivalis heat-shock protein (HSP) 60 as a vaccine candidate to inhibit multiple bacteria-induced alveolar bone loss.Recombinant P. gingivalis HSP60 wa...

Avian flu modeled on supercomputer, explores vaccine and isolation options for thwarting a pandemic

...to school closures and travel restrictions, as the vaccine industry struggles to catch up with the evolving v...ve that a large stockpile of avian influenza-based vaccine containing potential pandemic influenza antigens, coupled with the capacity to rapidly make a better...

HIV vaccine takes different tack to boosting immune response

...in Houston have reason to believe their unorthodox vaccine could one day help to prevent or control HIV infec...infection," said Chen. "Hopefully this therapeutic vaccine can boost the natural immune responses strong enough so you don't have to take these anti-HIV drugs ...

Congenital rubella syndrome nearly eradicated in the US

... congenital rubella syndrome, but a more effective vaccine introduced in the 1970s has helped in eliminating transmission of rubella from expectant mothers to their unborn babies. "Effectively, congenital rubella syndrome has been nearly eradicated from the United States," according to the statement. There...

New vaccine for condition that kills 500,000 children a year

...w England Journal of Medicine, the investigational vaccine Rotateq demonstrated that it can safely prevent 98...ar worldwide. In one of the largest pre-licensure vaccine clinical trials ever conducted worldwide, research championed by an Eastern Virginia Medical School ...

Jefferson researchers building a better rabies vaccine

...he finding has enabled the researchers to refine a vaccine they previously created against rabies in wildlife...hogenic and lethal, and have developed a very safe vaccine for the immunization of wildlife," says Bernhard Dietzschold, DVM, professor of microbiology and imm...

Outsmarting the smartie bug

...ether a complete description of the targets of the vaccine that will help monitor the disease and provide new...sule production in any bacterial species. The new vaccine will protect children from many of the most common serotypes but monitoring is needed to check wheth...

U of S researchers develop new vaccine candidate against hepatitis C

...tious Disease Organization (VIDO) have developed a vaccine candidate for hepatitis C, leading to hope in the ...ccines and Immunotherapeutics (CANVAC), produced a vaccine candidate that decreased the amount of a carrier virus expressing hepatitis C virus (HCV) protein in...

Plant-derived vaccines safeguard against deadly plague

...ough an innovative feat of plant biotechnology and vaccine design, researchers in the Biodesign Institute at ...rsity have successfully turned tobacco plants into vaccine production factories to combat the deadliest form of plague. The vaccine elicits a protective immune...

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