Smokers invite to test vaccine against nicotine addiction
UCSF's Habit Abatement Clinic is testing a vaccine that enlists help from the immune system to keep nicotine away from the brain. The vaccine is designed to help smokers quit and to limit the urge to start smoking again. Called NicVax, the i...AIDS vaccine research offers new insights on survival
...y difficult to control. Attempts to develop an HIV vaccine that triggers the production of antibodies -- the mechanism responsible for vaccine protection against other viruses including polio and hepatitis B -- have been unsuccessful. "HIV mu...Innovative method for creating a human cytomegalovirus vaccine outlined
...of Medicine has declared that development of a CMV vaccine should be one of the highest priorities for vaccine makers. Now, in a new study in the August 1 issue of The Journal of Virology, researchers at The Wis...Scientists tie several cancers to common 'oncogene engine'
...ma. "We have just opened a trial to offer the same vaccine to patients with all of the other cancers in this related family," said Fisher. "Prior to this, virtually no rational experimental treatments were available for these diseases, and patients have already started coming from throughout the country to e...... for variation further dims hopes for an effective vaccine for affected populations in rural Africa. ...A sweet solution for Alzheimer's disease?
...revious drug candidates for Alzheimer's disease. A vaccine designed to destroy amyloid รข, for example, was fi... mice used in the scyllo-inositol studies, but the vaccine turned out to be toxic in some humans. It caused an autoimmune reaction in about 10 percent of patie...Higher risk for cervical cancer seen among women infected with multiple HPV types
...th HPV 16 and 18, the targets of Gardasil. The vaccine also will prevent infection by the HPV types 6 and...ical cancer in thousands of women. However, the vaccine will not protect against HPV 58, which the new study discovered to be far more oncogenic than others...Experimental vaccine protects lab animals against several strains of H5N1
...ed the virus and used it to vaccinate ferrets. The vaccine protected the ferrets from getting sick when exposed not only to the flu strain from which the vaccine was made, but also two other strains, including a deadly strain labeled A/Vietnam/1203/04. Cross-st...Researchers find 'secret weapon' used by SARS virus
...ible new route by which scientists might fashion a vaccine against SARS, researchers at the University of Tex...timately lead to the creation of a live attenuated vaccine for SARS." Although many viruses interfere with host cells making messenger RNA or translating it...Tumor wizardry wards off attacks from the immune system
... trial that pairs T-reg depletion with anti-cancer vaccine as a therapy for pancreatic cancer patients. "We're attacking the problem from different angles hoping to translate these findings to our patients," Linehan says. "Right now, no effective treatment exists for pancreatic cancer." ...Defense peptide found in primates may block some human HIV transmissions
...as developed a similar approach to growing anthrax vaccine in tobacco plants. An inexpensive way to produce the drug with only a small amount of tobacco would help to make it accessible in areas such as Southeast Asia, Africa and the Caribbean where the disease spreads most quickly. "If we could develop ...Combination therapy with a monocloncal antibody and a vaccine leads to tumor rejection
...A4 monocloncal antibody used in combination with a vaccine expressing GM-CSF (Gvax) was able to eradicate skin and breast cancer in mice. In a new study appearing online on June 15 in advance of print publication in the July issue of the Journal of Clinical Investigation, this same research group investigate...Scientists to employ Arctic ice and polar bears to protect diversity of world's crops
...Children's Research Hospital have announced that a vaccine they developed a few years ago against one antigen...during a pandemic (worldwide epidemic) until a new vaccine could be developed specifically against the variant causing the outbreak, the researchers said. An a...H5N1 vaccine could be basis for life-saving stockpile
...Children's Research Hospital have announced that a vaccine they developed a few years ago against one antigen...during a pandemic (worldwide epidemic) until a new vaccine could be developed specifically against the variant causing the outbreak, the researchers said. An a...Study details hepatitis C ability to block immune system response
...rrhosis, and hepatocellular carcinoma. There is no vaccine available to prevent HCV, and current therapies are costly, have serious side effects and are curative in only a fraction of patients. According to the World Health Organization, the major causes of HCV infection are use of unscreened blood transfusi...T cells activated to fight HIV basis for dendritic cell therapeutic vaccine
...cept behind the development of a novel therapeutic vaccine loaded with a patient's own souped up dendritic ce...at proved the approach is safe. In that trial, the vaccine was derived using a readily available HIV protein. Even with this somewhat generic approach, T cell ...Combating anthrax: Results of study published this month as researchers look for a better vaccine
...y published this month by a Saint Louis University vaccine researcher scrutinizes what in the future could be...ailable anthrax vaccine. This new type of anthrax vaccine produced the immune response doctors were looking for, according to peer-reviewed research published...NHGRI announces latest sequencing targets
...r studying other human infectious diseases and for vaccine research, most recently for the virus causing Severe Acute Respiratory Syndrome, or SARS. Comparing the human genome with the genomes of other non-human primates and other organisms has been shown to be an effective tool for identifyin...Survivors of childhood polio do well decades later as they age
...isease, and the last case of polio not caused by a vaccine occurred in the United States in 1979. The three major types of polio include spinal polio, a paralytic polio that attacks nerve cells in the spinal cord; bulbar polio, in which the virus attacks motor neurons in the brainstem; and bulbospinal polio,......ersons immunized with vaccinia virus, a live virus vaccine against smallpox that is effectively cleared by the immune system. According to Walker, those findings indicate that activation of the PD-1 pathway occurs during the immune system's general response to viral infection. In test tube studies, the...