Innovative movies show real-time immune-cell activity within tumors
... to fluoresce blue. In one group of the mice, a vaccine developed by Wistar professor and study co-author ...unologists as antigens. In a second group, no such vaccine was given. Movies captured with the two-photon microscope then recorded the unfolding scene in the...Quality not quantity important for immune response to HIV
...may have a profound impact on the development of a vaccine against the disease. "Conventional medical wisdom...ch year. Despite being first identified in 1981, a vaccine to prevent infection has so far proved elusive. When HIV infects the body, it hides out in so-cal...Plague proteome reveals proteins linked to infection
...ublic health and biodefense and can guide drug and vaccine designers in their quest to disrupt the microbe’s ability to infect. Y. pestis is the bacterium that caused the infamous Black Death plagues. Fleas are vectors for the disease and can spread it to rodent and human hosts. This study mimicked envir...Malaria vaccine prompts victims' immune system to eliminate parasite from mosquitoes
...nstitutes of Health have developed an experimental vaccine that could, theoretically, eliminate malaria from ... upon the blood of the vaccinated individual. The vaccine would not prevent or limit malarial disease in the person who received it. An article describing t...Handling HPV vaccines and screening: The views of 100 authors
...ay in some instances be recommended as a universal vaccine for both genders towards the prevention of cervical cancer. "An unprecedented and phenomenal challenge for Public Health in the 21st century", according to Dr. Xavier Bosch, Guest Editor and driving force behind this monograph; "The background, the r...Bird flu vaccine additive may stretch supply
...an effective immune response to an avian influenza vaccine with doses as low as one-quarter of the norm when ...comes to be, adjuvants might be used to extend the vaccine supply. Furthermore, the authors note, H9N2 is itself a pandemic threat. The researchers vaccina...H9N2 avian flu vaccine paired with adjuvant provokes strong human immune response at low doses
...e called an adjuvant, low doses of an experimental vaccine against a strain of avian influenza (H9N2) provoke...M.D. An adjuvant is a substance that is added to a vaccine to boost the body's immune response to the vaccine's antigen. "In the event of an influenza pandemic...When nerve cells can't make contact
...d in the 1990s that the measles, mumps and rubella vaccine could cause autism in small children has no scientific basis at all. Today, it is clear that genetic factors are the major cause of the illness. Studies of identical twins have been particularly convincing in demonstrating this fact - the probability...New finding points way to foiling anthrax's tricks
... breathing problems and shock within days. While a vaccine is available, there is no effective treatment. The bacteria succeed by forming capsules that invade lung cells, then capturing iron in order to reproduce, and finally, manufacturing a toxin that kills the cells and releases thousands of new spores...Immune cell communication key to hunting viruses, Jefferson immunologists show
...pulate it and could have implications for improved vaccine development. To better understand how proteins are recognized by killer T-cells, Dr. Sykulev and his co-workers created a biosensor out of semiconductor nanoparticles called quantum dots. These served as a unique scaffold to carry presenting proteins...Vaccine combined with short-term postexposure antibiotics protects monkeys from inhalational anthrax
Anthrax vaccine administered in combination with a short course of...received three doses of the licensed human anthrax vaccine (anthrax vaccine adsorbed) postexposure. In the group that received ciprofloxacin but no vaccine, o...Americans support free access to research
...d Robert Reinhard, community advisor to NIH's AIDS vaccine trials. "Time and again the lesson is that improved knowledge in the community furthers the public health agenda." In another strong signal of broad support for public access, Sen. John Cornyn (R-TX) and Sen. Joseph Lieberman (D-CT) recently introdu...Plant-cell-produced technologies-cutting edge approach to bringing solutions to the market
Four months after the world's first vaccine made in plant cells has received regulatory approv...kers and industry representatives. The pioneering vaccine developed by Dow AgroSciences works against the Newcastle disease virus (NDV) in poultry. The latest...Gene transfer using mutant form of good cholesterol cuts vascular plaque and inflammation
... with researchers from Sweden, also are developing vaccine against LDL cholesterol (bad cholesterol) that one day may be administered in childhood to provide lifelong protection against vascular inflammation and plaque. The gene therapy research was supported by grants from the National Institutes of Healt......gy, it would take several months to produce enough vaccine against such a new virus for even a small proportion of the world's population. By that time, it would probably be too late; the virus would already have spread to most parts of the world. Health authorities must therefore consider all the methods ...St. Jude test of bird flu vaccine proves successful
A commercially developed vaccine has successfully protected mice and ferrets agains...tudy at St. Jude Children's Research Hospital. The vaccine was developed by Vical Incorporated in San Diego, California. This finding, coupled with results of...Mayo Clinic Cancer Center: Harnessing the measles virus to attack cancer
...cer Center has opened a new clinical study using a vaccine strain of the measles virus to attack recurrent gl...inic is unique in its pursuit of oncolytic measles vaccine strains for cancer treatment, and the research has grown from the most basic laboratory science to t...MRSA vaccine shows promise in mouse study
...rchers at the University of Chicago have created a vaccine that significantly protects immunized animals from...ding source of community-associated illness. The vaccine protected mice against potentially lethal infections with five virulent S. aureus strains, the resea...Vaccine shown effective against chancroid
...orld Health Organization, and efforts to develop a vaccine against the virus have achieved limited success. But what if a vaccine against another sexually transmitted infection found widely in that region of Africa ?chancroid ?was...Origen publishes in Nature a robust and versatile method for creating transgenic chickens
...facturing practices have long been established for vaccine production in chicken eggs. Moreover, the overall cost of facility and operations is a fraction of that associated with fermentation methods of manufacture. The ability to readily create transgenic chickens through this technology, and then to scale ...