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Tag: "vaccine" at biology news

Cancer vaccines -- Taking a jab at cancer by stimulating the immune system

...from scientific discussion to social debate, other vaccine studies are continuing to make progress. While HPV vaccine efforts had the "benefit" of a viral source for the disease, other researchers are developing vaccin...

Scientists unveil piece of HIV protein that may be key to AIDS vaccine development

...ing that could have profound implications for AIDS vaccine design, researchers led by a team at the National ...that can broadly neutralize HIV. "Creating an HIV vaccine is one of the great scientific challenges of our time," says NIH Director Elias A. Zerhouni, M.D. "N...

Researchers find hepatitis A and hepatitis C attack same protein to block immune defenses

... of hepatitis C’s chronic nature and the lack of a vaccine against it. But while better sanitation has driven a decline in hepatitis A cases in the United States, Lemon said, "It’s a significant risk for many people traveling overseas, because they fail to receive the vaccine." Hepatitis A has also been the ...

New research shows that flu is a trigger of heart attacks

...are at risk of heart disease receive the influenza vaccine every autumn, according to the authors of a new re...iac patients. If people can recognise that the flu vaccine has specific cardioprotective effects, then high-risk people will be more likely to make sure that t...

Experimental vaccine given during pregnancy reduces stillbirths from common virus

...nstitutes of Health have developed an experimental vaccine that reduces stillbirths among rodents born to mot...ith CMV each year at about 40,000, and there is no vaccine or treatment for pregnant women who have the infection. In a 2000 report, the Institute of Medicine...

Bacteria research offers hope for new vaccine against meningococci

...ly and effectively monitor the function of various vaccine candidates and new drugs, obviating the numerous costly and time-consuming tests that have been necessary until now. At the same time, the system provides a clear picture of the process of infection. “With these findings as tools, we can continue...

Anti-herpes treatment reduces HIV levels in women infected with both viruses

...s providing clinical benefits. Importantly, an HSV vaccine that would either prevent HSV infection or diminis...evention. The development and evaluation of an HSV vaccine should rank high on the international research agenda.' Gareth Thomas, UK Minister for Internation...

2,000 influenza virus genomes now completed and publicly accessible

...ine their virulence, and look for new therapeutic, vaccine and diagnostic targets," says NIAID Director Anthony S. Fauci, M.D. The Influenza Genome Sequencing Project, initiated in 2004, has been carried out at the NIAID-funded Microbial Sequencing Center managed by The Institute for Genomic Research (TIG...

Bird flu -- Call for antiviral drugs to be shared

...his ability, it would take 6-8 months to develop a vaccine effective against the new virus. Public health off...there will be plenty of time to bring an effective vaccine into use. But if the number is high then it could be difficult or impossible to contain the virus wi...

Creating new life forms that may help eradicate cancer affecting women

...d protein, HER-2/Neu, to immune cells, to create a vaccine called Lovaxin B. What these cells do is enlist killer T cells to seek and destroy tumor cells that over-express the HER-2/Neu molecule. This is significant because HER-2/Neu is over- expressed in 20%- 40% of all breast cancers. As Dr. Shababi e...

Vaccine to cope with viral diversity in HIV

...nd in many viral strains into lengths suitable for vaccine immunogens. "We can capture 62% of the variation found in the Nef protein and 81% of the variation in the Gag protein into immunogens of three gene lengths", says Nickle. These short-length immunogens are potentially useable in a vaccine, as they...

Early-stage immune system control of HIV may depend on inherited factors

...iming an early T cell response may be important to vaccine design, and the impact of an individual's genetic HLA Class I background implies that a successful vaccine would have to overcome genetic factors associated with a less protective response," he adds. Altfel...

OHSU researchers demonstrate how white blood cells cannibalize virus-infected cells

...m, it also offers hope of a new method for gauging vaccine effectiveness. The research is published in the cu...ch CD8+ T-cells respond to and consume a candidate vaccine could likely determine whether that vaccine is effective in educating the body's immune system as to...

Evolution of influenza A virus

...ns of influenza virus evolution more difficult, as vaccine strain selection then becomes dependent upon intensive surveillance, whole-genome sequencing, and phenotypic analysis....

Vaccine-producing 'plant-factories'

...interest therapeutically and in the development of vaccine antigens. This discovery, published in the latest issue of The Plant Cell, contributes, moreover, to refuting one of the current scientific dogmas regarding the mechanisms of protein transportation in plant cells. The research was carried out b...

New findings could lead to vaccine for severe malaria

...lacenta," she says. "This would mean that a future vaccine cannot be based on the principle of one protein-one receptor, as was previously believed." Now that scientists know that several placental receptors are involved in the binding mechanism, attention will be shifted to the parasite itself, and whether...

'Protecting virus' offers instant flu protection and converts flu infections into their own vaccines

...uch an extent that the harmful infection becomes a vaccine against that very form of influenza. It can also c...ent that harmful infections are transformed into a vaccine against that form of influenza. 'Protecting virus' has a significant alteration to one of the viru...

Tiny Tampa Bay fish key to evolution of immune system

...ov said. "For example, if we're trying to create a vaccine against a specific pathogen such as anthrax, smallpox or bird flu, we have to take into account the defensive measures those and other organisms might have." Organisms such as plants, fungi and primitive animal life are classified as having an innat...

Early HIV treatment fails to restore memory T cells

...n should be studied, and in particular that an HIV vaccine may need to stimulate immune responses that can act very quickly following infection, before the bulk of lymphocytes capable of countering the infection are lost. ...

HIV-1 kills immune cells in the gut that may never bounce back

...hich to approach HIV vaccines. "What good is a vaccine going to be if you get immune responses in periphe...rkowitz says. "It's pretty clear that a successful vaccine will need to address issues surrounding mucosal immunity, which is an area that -- relatively speaki...

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