Science's Breakthrough of the Year: Watching evolution in action
...s and topics in the upcoming year include drug and vaccine development for avian flu, RNA-interference in humans, high-temperature superconductors, the microbial family tree, detection of the merging of two neutron stars and ultrahigh-energy cosmic rays ?the speediest atomic nuclei in the universe. Researche...New vaccine platform may fight infections with causes from influenza to bioterrorism
...n of immune cells that HIV destroys in humans. The vaccine platform developed by Children's Hospital of Pitts...ool of Medicine, and co-authors describe how their vaccine consisting of a specific antigen to pneumocystis and a molecule normally expressed on activated T-ce...Scientists develop fungus-fighting vaccine
A group of scientists in Italy have developed a vaccine with the potential to protect against fungal patho...-fungal vaccines are currently available. The new vaccine was made of a sugar-like molecule called beta-glucan that is found on the cell wall of the fungus an...Preventing a pandemic: Study suggests strategies for containing a flu outbreak
...and prevaccination -- even with a poorly effective vaccine -- could potentially contain an outbreak in Southe..., helping to reduce morbidity until a well-matched vaccine could be produced," she said. The danger of avian flu is that the virus could develop into a new st...New study shows measles immunization may prevent fatal brain infection
...the notion that the strain of virus in the measles vaccine caused the infection. The study, in the November ...easles, it could not be ruled out that the measles vaccine strain caused the infection. William Bellini, PhD, and colleagues at the Centers for Disease Control...Volunteers sought for avian flu vaccine study
...r is enrolling volunteers in a study to test a new vaccine that targets avian flu, the first such vaccine against the virus. The Vanderbilt trial, led by Kathryn Edwards, M.D., will test the new vaccine in ...UF scientist finds unexpected link between cat and human AIDS viruses
...ps between the two viruses could one day lead to a vaccine for human A University of Florida researcher has ...version of the disease as those immunized with the vaccine currently used by veterinarians. The surprise finding may mean cats with feline immunodeficiency vi...US/African project deciphers deadly parasite genome
...ship has given a boost to the goal of developing a vaccine against a disease that has had a severe impact on ...tious goal of developing a genomics based sub-unit vaccine to control this protozoan pathogen. "Such an achievement would be a major breakthrough for vaccine d...Updated data on novel HPV vaccine confirms efficacy in large population
Updated data from a study on a promising new vaccine against a pre-cancerous cervical virus shows super...d the protocol (e.g. by missing visits, etc.), the vaccine prevented 99 percent of HPV 16 or 18-related high-grade cervical pre-cancers (1 of 9,342 pts versus ...Grand Challenges in Global Health initiative funds Yale project
...ll study a novel solution to a problem facing many vaccine developers. Some of the most promising vaccines fo...t that they are safe. "A big need in the world of vaccine development is the ability to predict whether vaccines for humans are safe and effective," said Flav...UW scientists report a new method to speed bird flu vaccine production
In the event of an influenza pandemic, the world's vaccine manufacturers will be in a race against time to fo...med viruses that are the seed stock for making flu vaccine in large quantities, life-saving inoculations may be available more readily than before. The work is...Researchers develop new testing methods for potential monkeypox or smallpox outbreak
...n the monkeypox and smallpox viruses, the smallpox vaccine likely kept these inoculated people from becoming seriously ill. The researchers believe these people were fully protected against monkeypox because smallpox vaccination can provide cross-protective immunity against this virus. "In our study, we fou...Survey Uncovers Surprising Attitudes Towards HIV Vaccine Research
...d felt it personally important to help support HIV vaccine research, a majority expressed reluctance to suppo... friend or family member’s participation in an HIV vaccine clinical trial. These were among the conflicting findings of a telephone survey of more than 3,500 ...Experimental shingles vaccine proves effective in nationwide study
In one of the largest adult vaccine clinical trials ever, researchers have found that an experimental vaccine against shingles (zoster vaccine) prevented about half of cases of shingles--a painful nerve and ski...LIAI scientists make major finding on potential smallpox treatment
...e creation of worldwide stockpiles of the smallpox vaccine over the last several years. Kronenberg said that if further study continues to validate the safety and effectiveness of Dr. Crotty's finding, "we may one day see high-quality batches of anti-H3 antibody stockpiled around the world right along side...Breast tumors in mice eradicated using cancer vaccine
...chool of Medicine has shown that by using a cancer vaccine based on the bacterium Listeria monocytogenes, the...e that are not immunogenic when presented by other vaccine approaches. Paterson first hit on the idea of using Listeria as a cancer vaccine vector over ten y...Vaccine targets tumors where they live
...ans with melanoma. The researchers show that this vaccine is safe and feasible to use for local delivery int...mmunity and provides a foundation upon which other vaccine strategies can be contemplated for local delivery. ...Learning how SARS spikes its quarry
...ike protein they used could provide the basis of a vaccine against SARS, since it appears to be recognized by the immune system of the host. In future studies, Harrison and his colleagues plan to explore the steps that occur after the spike protein attaches to the receptor. The researchers know that the sp...Researchers report breakthrough against world’s deadliest viruses
...er." According to Dr. Geisbert, this is the first vaccine system, or platform, that has protected nonhuman p...tes from both Ebola and Marburg. "In addition, the vaccine targets dendritic cells, which are the same cells that Ebola and Marburg attack," said Dr. Geisbert.......fantum, transmitted by sand fly bites. There is no vaccine for this disease, which can rapidly lead to death ...as parasite reservoir for humans. Development of a vaccine for dogs could help brake transmission of the disease to humans, by reducing this reservoir. Such pr...