Same-Sex Mating Discovered in a Toxic Fungus
...Ph.D., also of Duke. "Organisms, including fungi, usually exist in an approximately one-to-one sex ratio," Lin said. "Yet in Cryptococcus neoformans, one mating type predominates, leaving them with apparently few chances to mate. It's been a mystery." In 1996, another group discovered that those alpha isol...Canada approves marijuana-based pain spray
...c pain are of freezing, cold or burning sensations usually of the limbs and most often of the lower extremiti... and application site reactions. Side-effects were usually mild or moderate in severity and often resolved with down-titration or interruption of treatment.8 ...UNC launches study of liver injury caused by drugs
...case even though drugs that cause liver injury are usually entirely safe for the majority of patients taking them," he added. The main purpose of DILIN is to find and study people who have experienced liver injury due to medications, said Watkins, who is Verne S. Caviness distinguished professor of medicine,...New understanding of DNA repair may pave way to cancer treatments
...tissue culture and in animal models. "Melanoma is usually resistant to chemotherapy, but we found that by inhibiting ATF2, it became more sensitive to treatment," Ronai said. Consequently, his laboratory developed a small peptide that interferes with ATF2 function, efficiently blocking melanoma growth in mo...Researchers find promising cancer-fighting power of synthetic cell-signaling molecule
...trolled process called apoptosis. Cancer cells are usually defective in these regulatory pathways, so researchers hypothesized that structurally modified sphingolipid analogs might be even better at making cancer cells behave more normally. Merrill and his collaborators have been studying sphingolipids for ...Measuring hormone cuts antibiotic use in half in pneumonia patients
.... Tamm said. "Once the treatment is started, it is usually continued for 10 to 14 days, because nobody knows when you can stop without a risk for the patient," he said. Because levels of procalcitonin have been found to be elevated in patients with bacterial infection but not viral infection or other inflam...A little stress gives beneficial oomph! to immune system
...or wounded in some other way ?activated leukocytes usually return to their resting position in a few hours." Some of the mice in the study were restrained in clear plastic ventilated tubes for two-and-a-half hours. These mice ?the stressed group ?could not turn around in the tube, but they could move forwar...NIAID begins clinical trial of West Nile virus vaccine
....S. appearance in New York City in 1999. The virus usually is transmitted to humans through the bite of a mosquito that has been infected after feeding on an infected bird or animal. The virus also can be spread through blood transfusions, organ transplants and breastfeeding, as well as from mother to child ...Study reveals dramatic difference between breast cancers in US and Africa
...merica, most breast cancer occurs after menopause, usually in the late 50s or 60s. In Africa, it most often strikes women in their 40s. The average age of the African women in this study was 44. Studies suggest that the rate and genetic profiles of breast cancers in African American women are likely to fall...Elephant seal pups suffer from ocean warming
...ature changes, as an increase in water temperature usually causes their prey to migrate to cooler areas, depleting local food resources and resulting in pup starvation. Elephant seals, which feed in deep waters, were previously thought to be better buffered against ocean temperature changes than other sea ma...Norovirus found to cause traveler's diarrhea
...on cause of nonbacterial gastroenteritis outbreaks usually associated with developed countries, according to a new study by researchers at the Johns Hopkins Bloomberg School of Public Health and other institutions. The researchers also found that the longer travelers stayed at their destination, the more lik...Findings have implications for tracking disease, drugs at the molecular level
...single nanoparticles under conditions where people usually look at thousands or millions of stain molecules. This could allow us, for instance, to track a single molecule of a drug in a cell or other biological sample." Other advantages of the technique are that the gold particles can be prepared easily, ha...Study uncovers bacteria's worst enemy
...es are the elements above atomic number 89 and are usually radioactive. The study's results indicate that actinide toxicity is primarily chemical, rather than radiological, and so a bacteria's resistance to radiation does not necessarily ensure a tolerance for radionuclides. In fact, the bacteria's worst ene...Cellular Defects in Premature Aging Disease are Reversible
...se being the leading killer, and affected children usually die before they reach their late teens. Less than two years ago, NIH-led researchers discovered that the genetic basis for HGPS is a single mutation in the gene encoding lamin A. Lamin A is a critical structural protein that acts as the scaffolding ...... chest, the abdominal cavity and around the heart, usually caused by exposure to asbestos. Due to its active mining and manufacturing of asbestos in the mid-1900s, Australia has the highest incidence of mesothelioma in the world. Rates of the disease have tripled in the past 20 years and are expected to pea...Discovery clarifies role of peptide in biological clock
...rising that the process is regulated by a peptide, usually a slow signaling agent, rather than a neurotransmitter, associated with fast events, Herzog said. "We're trying to understand the mechanics of how the system synchronizes and the secondary messenger systems as well," Herzog said. "We're getting clos...Stealth Worms May Improve Insect Pest Control
..., beneficial insects or the environment. Nematodes usually have to be underground; their targets are soil insects." The formulations keep improving as newer isolates of nematodes are found, and there is a lot of commercial interest in matching nematodes to pests, Stock says. "Yet these nematodes are so pow...'Smart drug' targets deadly brain cancer
.... When first diagnosed, glioblastoma multiforme is usually treated with surgery, radiation therapy and chemotherapy -- and median survival is 12 to 16 months. For patients in whom the disease recurs, the prognosis is indeed dismal: there are no good treatment options. The Next Step Mayo Clinic researchers ...Butterfly migration could be largest known
...he winter. Painted ladies migrate every year, but usually less conspicuously and in far fewer numbers. This year, however, exceptionally high winter rainfall in southern California has created a bumper crop of plants for the caterpillars to eat, fuelling a population boom, Shapiro said. The butterflies tak...Whole-body MRI Takes Less Than 20 Min To Scan A Patient's Entire Body For Cancer Spread To Bone
... about 20% better than bone scintigraphy, which is usually performed for this purpose. “Whole-body MRI is a relatively new technique that uses an automatic moving table and fast software. It offers a better sensitivity and higher specificity in detecting bone metastasis than other methods,?said Joan C. Vila...