Study examines genetic risk factors for Alzheimer's disease
...udy is just the first in series we are undertaking using new technology to look comprehensively at every gene in the human genome in Alzheimer’s Disease and we hope that there are other exciting findings to come.? There is no known cure or preventative treatment for Alzheimer’s disease, which affects one...Super-fermenting fungus genome sequenced
... the capacity of P. stipitis to ferment xylose and using this knowledge for improving xylose metabolism in other microbes, such as Saccharomyces cerevisiae, brewer’s yeast, offers a strategy for improved production of cellulosic ethanol,?said Eddy Rubin, DOE JGI Director. “In addition, this strategy could...Biodiesel study targets cleaner air, cleaner engines
...nvolved six farms to evaluate the effectiveness of using biodiesel in agriculture. "This project was designed to accelerate the adoption of biodiesel use on Ontario farms through a series of on-farm evaluations," said Deanna Deaville, Special Project Coordinator with the Ontario Soil and Crop Improvemen...New success in engineering plant oils
...o find ways to manipulate the accumulation of fats using genetic techniques." The researchers focused on an enzyme known as KASII that normally elongates fatty acid chains by adding two carbon atoms. The longer 18-carbon chains are more likely to be acted on by enzymes that desaturate the fat. So the sc...Heart failure: Intervention possibilities from imaging programmed cell loss
...y cell loss—or apoptosis—in heart failure patients using annexin A5 imaging," explained Leo Hofstra, director of cardiovascular imaging at the University Hospital of Maastricht in the Netherlands. "Such a strategy may offer a new possibility for studying interventions to minimize damage to the heart muscle...Sandia researchers take new approach to studying how cells respond to pathogens
...ining them into one compact, miniaturized platform using our unique microfluidic and imaging tools," Singh ...erates hypotheses to be tested next. Singh says using an integrated microfluidic platform sets Sandia apart from the rest of the world. Sandia researchers...Transfusion expert urges wider use of filtered blood
...ized clinical trials, on the risks and benefits of using leukoreduced blood. They assessed the statistical ... among the first hospitals in the country to begin using leukoreduced blood for all cardiac surgery cases. Since then, the hospital has extended its leukored...UCI scientists reconstruct migration of avian flu virus
.... Local vaccinations can be better administered by using strains from regions that have repeatedly contribu...re likely to isolate the strain that you should be using to make the vaccine." The study appears this week in the online early edition of the Proceedings ...Jefferson scientists find rabies-based vaccine could be effective against HIV
...t viral proteins into the rabies virus genome, and using such viruses-based vaccines in preventing disease in rhesus macaques. One was a glycoprotein on the surface of HIV, while the other was an internal protein from simian immunodeficiency virus (SIV). They used the latter because HIV does not cause dise...Gut research yields new anti-cancer approach
... inhibitors). The team conducted these experiments using colorectal cancer cells as study models because they arise from normal gut cells and share some of their qualities (e.g. normal inflammatory signals). Unlike normal gut cells, however, cancer cells do not die when removed from the gut wall. Living on...Using nanomagnets to enhance medical imaging
...bserved MRI response under non-clinical conditions using imagers at The Children's Hospital in Denver. The information gained is fed back into recipes for making even better nanomagnets. The work described in the new paper was supported in part by the National Science Foundation. ...Researchers from the University of Navarra analyze new kinds of cancer-fighting antibodies
...l illnesses. Specifically, the article discusses using monoclonal antibodies in order to stimulate the immune system. In this therapy the antibodies are directed to the immune system cells in order to provoke a stronger reaction against cancer. This has the advantage of exploiting a mechanism with an act...Gene tests and brain imaging reveal early dementia
...oup had reduced parietal lobe activity, detectable using an MR camera, and that these same people were the ones who went on to suffer memory deterioration two to three years later. "It's surprisingly difficult to diagnose Alzheimer's with any certainty, but things are made easier if you know who runs t...UC Davis researchers use heated nanoprobes to destroy breast cancer cells in mice
... single 20-minute treatment. Dosing was calculated using an equation that included tumor concentration of bioprobes, heating rate of particles at different amplitudes, and the spacing of AMF bursts. Tumor growth rate slowed in the treated animals, a response that correlated closely with heat dose. No to...Allergy to hair dye increasing
... in their 20s, and 2% of men in their 20s reported using hair colouring products. By 2001 the proportions had increased in these three groups to 41%, 85%, and 33%, respectively. Severe hair dye reactions among children have also recently been reported. Wider debate on the safety and composition of ha...Scientists identify molecular cause for one form of deafness
...ity of espin to cross-link F-actin is decreased by using genetically modified 'deafness' mutants with progressively more damaged actin binding sites, the structure changes from a well-ordered crystalline array of filaments to a nematic, liquid crystal-like state," said Wong, who also is a researcher at the...Study shows isolation of stem cells may lead to a treatment for hearing loss
...cells in terms of neural and hair cell development using a panel of stem cell development and hair cell markers. The formation of spheres from early postnatal cochlear tissues and their expression of a wide range of developmental markers unique to hair cells confirm the possibility that self-supporting ha...Researchers design pulsed mircrojet system to deliver protein drugs without pain or bruising
... drugs for local and systemic applications without using needles. "The microjet system delivers precise... Mitragotri. "Speeding the delivery, combined with using extremely small jet diameters and less liquid per pulsation, was shown to be more effective." ...Scientists find genes involved in the battle between Hessian flies and wheat
...rustration." Hessian flies can be controlled by using specifically bred wheat varieties called resistant wheat cultivars. Infestations by the flies also can be prevented by planting wheat after the fly is no longer active and laying eggs. This "fly-free date" is set in different regions according to cli......Portuguese water dogs. A similar analysis was done using 526 dogs from 14 small breeds and nine giant dog breeds. Ultimately, the researchers analyzed DNA from more than 3,000 dogs from 143 breeds to pinpoint a specific gene sequence variant, or haplotype, associated with small size in the canine genet...