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Tag: "using" at biology news

CT scan reveals ancient long-necked gliding reptile

...he surface. Repeated attempts to remove the matrix using both mechanical and chemical techniques have been unsuccessful." "The fossils sit on sheets of stone less than a quarter inch thick," says Tim M Ryan, research associate in anthropology and member of Penn State’s Center for Quantitative Imaging. ...

Could fungal collection hold the key to new life-saving drugs?

... being exploited for natural products. Although using biotechnology to develop new drugs is by no means simple, the industry has seen steady success over the past few years. Between 2000 and 2005, over 20 new drugs were released onto the market originating from natural sources. And although this is the ...

New findings challenge established views on human genome

...nome marked just the first step toward the goal of using such information to diagnose, treat and prevent di...cent years, researchers have made major strides in using DNA sequence data to identify genes, which are traditionally defined as the parts of the genome that...

Penn researchers link cell's protein recycling systems

...s for breaking down proteins and have succeeded in using this link to rescue neurodegenerative diseases in a simple animal model. The study appears this week in Nature. The cell has two internal pathways for breaking down proteins. The ubiquitin-proteasome pathway marks unwanted proteins with ubiquitin...

Bacteria ferry nanoparticles into cells for early diagnosis, treatment

... more efficient than other experimental techniques using viruses and bacteria. "With other techniques, you can usually incorporate only one copy of your gene cargo to each bacterium or virus particle," Akin said. In the new approach, bacteria can carry hundreds of nanoparticles, each of which can in ...

Exploring the dark matter of the genome

...Both heterochromatin and euchromatin are sequenced using a method called whole-genome shotgun sequencing. Celniker says, "We grind up whole flies and produce libraries of DNA fragments of two sizes, some that are 2 kilobases long" -- a kilobase (Kb) is 1,000 bases -- "and some that are 10 kilobases long. C...

In nature, proteins sweep up nanoparticles

...eter in diameter. The team examined the biofilm using transmission electron microscopy at Berkeley Lab’s...n this intriguing signal, they examined the sample using an extremely high-spatial-resolution imaging tool called secondary ion probe spectrometry, which is ...

University of Pittsburgh School of Medicine researchers develop 'off-the-shelf' vascular grafts

...adable porous, tubular polyester urethane scaffold using a rotational vacuum seeding device. After culturing their vascular constructs for seven days, the investigators then implanted them in the abdominal aortas of rats eight weeks before performing tests to determine how well the grafts had performed...

Staphylococcus aureus hides out in cells

...850) did inside human lung epithelial cells (A549) using an in vitro model. They found that shortly after S. aureus entered the lung cells, the bacteria’s gene expression profile dramatically changed: gene expression for bacterial metabolic functions and transport shut down, putting the bacteria in a dorma...

Potent possibilities for parasite attack

...le of the many genes whose function is unknown, by using experimentally induced RNAi to 'knock-down' gene activity prior to host infection. "In addition to their function with respect to promoting diverse clinical outcomes," commented David Sacks, PhD, Head of the Intracellular Parasite Biology Section ...

Mutating the entire genome

...ticular gene or other DNA sequence knocked out. So using existing technology to knock out the estimated 20,... Wu and Capecchi improved their new method by using it in combination with a “transposon” or so-called “jumping gene” named piggyBac, which comes from a...

UCF nanoparticle offers promise for treating glaucoma

...Dakota State University, developed the research on using nanoparticles as a delivery mechanism for the comp...hetnikov started looking into the possibilities of using nanoparticles as drug delivery tools. Subsequent research with his advisors led to the specific app...

Weizmann Institute scientists develop a general 'control switch' for protein activity

...ecise timing of fruit ripening would be controlled using a substance that increases the activity of proteins responsible for ripening. Moreover, numerous proteins are used in industrial processes, as biological sensors and in other applications. The possibility of controlling these applications – strengthe...

Reconstructing the biology of extinct species: A new approach

...e first time, we can test our previous conclusions using a new source of information." ...

Study identifies 5 genetic themes key to keeping stem cells in a primitive, flexible state

... They also applied very rigorous analysis methods, using data from StemBase, the largest stem cell gene expression database in the world. Designed by bioinformaticist Dr. Miguel Andrade, the database includes data from thousands of DNA microarrays submitted mainly by scientists in Canada’s Stem Cell Networ...

AAAS decries latest stem cell veto

...estrictions on federal funding of medical research using embryonic stem cells, which proponents say would be derived from microscopic embryos left over and due to be discarded after in vitro fertility treatments. Current U.S. policy limits such funding to fewer than 20 stem cell lines that had been created...

Experts predict Tamiflu could halve the pandemic influenza death toll versus no intervention

...ategies to reduce the spread of pandemic influenza using Tamiflu prophylactically. It was predicted that th...analysis that indicates that a prevention strategy using Tamiflu may help contain a pandemic outbreak.3 The study also predicts that if the stockpile is ...

Antarctic icebergs -- Hotspots of ocean life

...surements – physical, biological and chemical, and using satellite images provided by NASA. At the same...C-developed technologies, Helly collected the data using the SIOExplorer-in-a-Box digital library system ( http://SIOExplorer.ucsd.edu ) and then stored the ...

St. Jude study shows genes play an unexpected role in their own activation

...er who turns on the water flow in a pipe system by using a certain tool,” Brindle said. “What we discovered...ny different genes, depending on which tissues are using it and which signaling molecule caused cAMP to put CREB to work,” Brindle said. “It is another clue ...

Avian influenza survivors' antibodies effective at neutralising H5N1 strain

...udying or that the monoclonal antibodies generated using our technique will be able to tackle such a virus," says Professor Lanzavecchia. "Nevertheless, we are encouraged by the broad neutralizing activity of these antibodies in the lab and the moderate doses required." Using administered antibodies has...

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