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Tag: "used" at biology news

Mouse brain tumors mimic those in human genetic disorder

...y be promising drugtargets; and brain images often used to determine the need fortreatment may not actuall... blood vesselsand microglia."Next, the researchers used the mouse model to investigate a clinicalconcern. Physicians rely on several tests to determine whet...

Spider Venom Could Yield Eco-Friendly Insecticides

... Unlike some conventional insecticides, the toxins used in the engineered virus would not end up in the food supply. Recent laboratory research on cockroaches and tobacco budworms demonstrates that the toxins can disrupt the insects?nervous systems or induce paralysis in just a few minutes. King and his ...

New imaging method gives early indication if brain cancer therapy is effective, U-M study shows

..., which they call a functional diffusion map. They used a magnetic resonance imaging scan that tracks the diffusion, or movement, of water through the brain and mapped the changes in diffusion from the start of therapy to three weeks later. The tumor cells block the flow of water, so as those cells die, w...

Gene variations explain drug dose required to control seizures

...ratio between a drug's toxic and therapeutic dose, used as a measure of the drug's relative safety for a particular treatment. Similarly, appropriate doses of carbamazepine take time to determine because of the drug's variable affects on patient metabolism and its potential neurologic side effects. The ...

Solution to Pollution: New Bacteria Eats Toxic Waste

...ser for contaminated soil. The bacteria, now being used around the world, is an inexpensive and highly eff...c aromatic hydrocarbons (PAH’s). The site had been used by industry as a place to apply preservatives to wood, yet Sims found the land to be relatively free...

Scientists decipher genome of fungus that can cause life-threatening infections

...s, revealeddifferences in the virulence strategies used by C. neoformans comparedto other pathogenic fungi...unistic human pathogenof global importance that is used by researchers as a model for fungalpathogenesis. Since the 1980s, the number of Cryptococcus infect...

Poplar trees redirect resources in response to simulated attack

...aboratory have applied some of the same techniques used in medical imaging to track the distribution of nu...ners. Their research using radiotracers like those used in human PET scanning is helping to unravel the mysteries of plant biochemistry. http://www.bnl.gov...

Purdue proves concept of using nano-materials for drug discovery

...ining the proteins, and the chambers could then be used to search for drugs that deactivate the pumps, Lee said. Such an advanced technology could be used to quickly screen millions of untested drug compounds that exist in large pharmaceutical "libraries....

Plant hemoglobins: Oxygen handlers critical for nitrogen fixation

...spheric nitrogen to ammonia, which is subsequently used by the plant for growth and colonization of nitrogen-poor soils. Symbiotic nitrogen fixation is important for sustainable agriculture and contributes millions of tons of reduced nitrogen to crops and pastures each year. As reported this week, resear...

Scientists rid stem cell culture of key animal cells

...evated concentrations of FGF2, a protein routinely used for human embryonic stem cell culture, to test whether FGF2 preserves undifferentiated stem cells in the absence of BMP. The result was that "the cells looked perfect." Xu says he has grown the resulting stem cells in the desired undifferentiated sta...

Vital step in cellular migration described by UCSD medical researchers

...urons. For this reason, they believe the mechanism used by alpha4 integrins to localize Rac activity may participate in a wide variety of cell migratory and pathfinding events. In addition to Nishiya and Ginsberg, additional authors were William B. Kiosses, Ph.D., The Scripps Research Institute, La Jolla...

U-M scientists find genes that control growth of common skin cancer

...y signaling in the growth of BCC.The investigators used genetically engineered mice in which they couldmanipulate expression of an Hh pathway component, called Gli2 ,effectively turning it on or off at will in the skin. As expected,expression of Gli2 resulted in BCC formation. In addition, theresearchers ...

Weill Cornell Research Reveals Secrets Of Trafficking Within Cells

...ollege of Cornell University in New York City have used an exciting new technology to better understand ho...study was conducted in fibroblasts, a kind of cell used in many cell-culture experiments. But Dr. Ryan said the findings have broad implications for cells t...

New Study from Affymetrix Laboratories Points to Changing View of How Genome Works

...h the National Cancer Institute, the research team used high-density GeneChip(R) microarrays to study ever... of the human genome, there are about 26,000 genes used to make proteins that ultimately control the structure and function of every cell in the body. Most ...

First-ever Compounds To Target Only Metastatic Cells Are Highly Effective Against Breast, Prostate, And Colon Cancers

...ny interested in this, especially because the mice used in our trial seemed to experience minimal toxicity -- a good sign that patients might tolerate these compounds, too," Dr. Huang said. "It's all very exciting," he said. "Metastatic disease is such a tough problem, and these compounds could provide p...

Discovery of key protein's shape could lead to improved bacterial pneumonia vaccine

...ly appearing onthe surface of these bacteria. When used in a vaccine, these pieces ofcarbohydrate stimulat...pull it apart to see ifsmaller pieces of it can be used to make a vaccine that triggersproduction of antibodies against the CbpA. Since all the S. pneumonia...

New comparative toxicogenomics database

...ly appearing onthe surface of these bacteria. When used in a vaccine, these pieces ofcarbohydrate stimulat...pull it apart to see ifsmaller pieces of it can be used to make a vaccine that triggersproduction of antibodies against the CbpA. Since all the S. pneumonia...

ASU researchers finds novel chemistry at work to provide parrot's vibrant red colors

... the parrot species they sampled. The researchers used a chemical analysis technique called high-performance liquid chromatography to survey the pigments present in red parrot feathers. McGraw and Nogare collected and analyzed samples from 44 parrot species that have red feathers. Overall, there are some...

Transport System Smuggles Medicines Into Brain

... the parrot species they sampled. The researchers used a chemical analysis technique called high-performance liquid chromatography to survey the pigments present in red parrot feathers. McGraw and Nogare collected and analyzed samples from 44 parrot species that have red feathers. Overall, there are some...

Scientists develop new color-coded test for protein folding

...wever, gold nanoparticles have not been previously used to investigate the folding and unfolding of proteins." The initial batch of gold-cytochrome solution had a rosy red hue and a pH value of 10--about the same as an over-the-counter heartburn medication. But when drops of hydrochloric acid were added,...

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