Polymers with copper show promise for implanted sensors
...ors and fewer clots on the sensor surfaces when we use nitric oxide-releasing polymeric coatings," said Meyerhoff. However, those materials have some characteristics that may limit their usefulness. "In some instances, the chemistry in the polymer is sensitive to moisture and heat, so whether it can be ......several differences exist in how the two pathogens use PGA to their advantage. PGA is currently used as an antigen for vaccine production against Anthrax This paper presents PGA as a promising target for drug development aimed at combating these hospital-acquired infections and other illnesses caused by...NIH Calls on Scientists to Speed Public Release of Research Publications
...ady rise. "With the rapid growth in the public's use of the Internet, NIH must take a leadership role i...esearch publications that NIH and its awardees can use to manage more efficiently and to understand better their research portfolios, monitor scientific pr...Reducing malarial transmission in Africa
...y countries to change their treatment policies and use more expensive drugs, including drug combinations that will hopefully slow the development of resistance and minimize transmission of resistant parasites. In this month's premier open-access journal PLoS Medicine Colin Sutherland and colleagues from...Stem Cell Research Shows Potential for Replacing Tissue Damaged in Heart Attacks
...ates today,?says Dr. Lough. In looking at ways to use ES cells, the research team had to consider the fact that the cells are “pluripotent,?meaning that they can develop into any of the 210 different cell types in the human body ?including tumors. That meant they had to determine how ES cells could be f...No relief for Pacific Northwest drought
...e similarity to conditions last seen in 2001. "We use five different global climate models as the underlying basis for our projections, and they are all showing the same thing," Neilson said. "It is going to become extremely dry in many parts of the Pacific Northwest and northern Rocky Mountain states, ...A human parasite with a streamlined mitochondrion
...-because they make large amounts of energy as they use oxygen. However, some eukaryotic cells, including important parasites of humans--such as Entamoeba histolytica, the causal agent of amoebic dysentery--live in environments that are too oxygen poor to support this process. Nevertheless, Entamoeba stil...50-year-old Mystery Solved: Protein Tags Regulate Key Ion Channel
...ch is why so many of the most potent mediations we use to care for our patients' target one or another ion channel." Goldstein's team discovered the type of ion channel known as background (or leak) potassium channels in yeast cells in 1995 and in fruit flies in 1996. Although potassium leak was first d...Researchers discover chemical compounds that affect plant growth
...e team's chemical genomics approach focuses on the use of small molecules to modify or disrupt the functi...yet is poorly understood. The researchers can now use the compounds they have discovered to identify target pathways and proteins within the endomembrane ...Stopping smallpox in its tracks: A new anti-viral approach
...erapeutics. These inhibitors, which are already in use in human anti-tumor therapy, may have widespread applications in human viral infections and protection from smallpox. These findings reveal a new approach to the identification and development of antiviral compounds. This is especially critical at a ...New Drugs For Bad Bugs: UF Approach Could Bolster Antibiotic Arsenal
...UF scientists developed a system of pumps they can use to expose bacteria to changing concentrations of a...the bacteria are killed or see if they regrow, and use mathematical modeling to estimate the optimal dose. “Based on the results in the lab, then you can ...Scientists discover how plants disarm the toxic effects of excessive sunlight
...molecules. "We've discovered a pathway that cells use to turn on certain genes and respond to singlet ox...ay be better able to design bioenergy systems that use sunlight as an alternative to traditional fossil fuels. "By understanding how biology solves this pr...HIV-1 spread through six transmission lines in the UK
...ing sex with men, a significant increase in condom use has been reported since 1990, which could explain the equilibrium reached for the number of infections. “Antiretroviral therapy may also have impacted on transmission rates, but our evidence does not demonstrate this. You would expect growth rates t...Products containing specific probes for detecting alternative splice forms protected
... company as the only partner for the conception or use of gene profiling microarrays that include alternative RNA splicing. "The granting of these claims build on the company's core assets further expanding our IP position in the field of gene expression and profiling," stated Bruno Tocque, President and...Gene therapy promising for growing tooth-supporting bone
...rnesses the virus' ability to enter into cells and use their genetic machinery. Once inside the cell, the viruses help BMP-7 genes get where they need to be in the host's cells to boost bone production. Gene expression producing BMP-7 proteins peaked after a week. Giannobile said that was ideal because ...Affymetrix Licenses Microfluidics Technology From Caliper Life Sciences
...r has issued Affymetrix a non-exclusive license to use a portion of Caliper's microfluidics patent estate...ed with GeneChip arrays, but excludes the right to use LabChip technology with respect to products intended primarily to perform nucleic acid separations a...New insight into regulation of blood stem cells
...s to understand how c-Myb controls HSC numbers and use this information to develop compounds that can regulate stem cell proliferation and differentiation. The ability to influence stem cell fate decisions would be expected to have a major impact on the field of stem cell therapy and to provide important...Alzheimer's cognitive decline slowed
... PET scans demonstrated an increase in the brain's use of glucose, an indication of increased brain activity, while mental-status tests showed a slowing of the patients' rate of cognitive decline was reduced by 36 to 51 percent. In addition, researchers examined the brain tissue of a study participant wh...Microbial fuel cell: High yield hydrogen source and wastewater cleaner
...ional fermentation processes. We can theoretically use our MFC to obtain high yields of hydrogen from any...dioxide and hydrogen. Logan notes, "Basically, we use the same microbial fuel cell we developed to clean wastewater and produce electricity. However, to p......s using the same MRI equipment that is in standard use for heart or brain scans," says senior author Greg...t more effective follow up, because a doctor could use them to discern whether a tumor was still growing after radiation or chemotherapy treatments. Altho...