The secret to longevity in tubeworms
...e seep where the worm lives. These chemoautotrophs use energy from hydrocarbons to reduce sulfate to sulfide, which L. luymesi absorbs through its unique "roots," extensions of its body that it tunnels into the sediments. However, current measurements of sulfide and sulfate fluxes in the water near the v...Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible
... institutions.Evaluation of the potential clinical use of microarrays may requirelarger studies carried out in multiple locations and would necessitatethat microarray data produced in different laboratories be combined foranalysis. Even if all procedures and equipment were the same, smalldifferences betw...Computers to be used to find blueprint for new influenza drug
...he University of Bath have won a £261,000 grant to use the latest software to produce a blueprint of a de...or Williams and his colleague Dr Gus Ruggiero will use part of the grant from the Biotechnology and Biological Sciences Research Council to buy computers w...Transplantation Of Monkey Embryonic Stem Cells Reverses Parkinson Disease In Primates
... here will advanceresearch aimed at validating the use of stem cells to treatneurodegenerative disease" and this is most welcome particularly asinvestigators face yet another presidential moratorium endeavoring tolimit the number of human stem cell lines that can be used for futureresearch and treatment....New Technique for Tracking Gene Regulators
...ched, and wash all the others away. Scientists can use traditionalgene-sequencing methods to decipher the sequence of A, T, G, and C onthese fragments and then locate their original positions on the genome,but it is a slow and somewhat expensive process. Other methods, such asmatching the pieces to their...HIV Patients May Be at Risk of Heart Problems When Taking Protease Inhibitor Drugs
...re several specific actions physicians can take to use this new information wisely, Drs. Ackerman and Badley say. The first is to screen by electrocardiogram for heart effects in vulnerable patients. The second is to be alert for multiple drug therapy situations, because certain drug-drug combinations co...Research on Worms Yields Clues on Aging
...the nervoussystem of C. elegans, they also plan to use the worms as modelorganisms to investigate how the drugs inhibit seizures in epilepticpatients, a mechanism that currently is not well understood. Suchresearch could lead to more effective treatments for epilepsy....U-M scientist to talk about tissue engineering at AAAS
...in these patients, and Krebsbach sees potential to use it for similar gains in tissue engineering new bone. Bone morphogenetic proteins help cells differentiate into specific kinds of bone, and encouraging cells to make more BMPs during tissue engineering also can ramp up the effects. "Together these t...Finding Cures For Tropical Diseases: Is Open Source An Answer?
...chemistry and biologyexperiments. Volunteers could use chat rooms and bulletin boards toannounce discover...lly--manufacturers. The absence ofpatents, and the use of volunteer staff, would contain the costs ofdrug development.Ten years ago, say the authors, TDI w...Breakthrough Microarray-based Technology for the Study of Cancer
...fication and throughput. Efforts inrecent years to use microarrays to overcome these limitations have bee...detect.Additionally, the technology allows for the use of total genomic DNA todetect chromosomal changes across the entire genome. The Platformenables ampl...Improved Outcomes Releases GeneLinker(TM) Gold and Platinum Version 4.6
...uding confidencevalues). Koadarray is very easy to use and produces better results thanother leading arra...tallation.- Improved Proteomics Import Scripts for use with the new NIH/NCICenter for Cancer Research Ovarian dataset 8-7-02 (see ProteinBiomarker/Proteomi...Gene therapy converts dead bone graft to new, living tissue
..." Such a transformation can occur because mammals use their skeletons for both support and as a kind of ...se their handling ?keeping them alive and ready to use ?is far harder than Schwarz's viral paste, which can be stored at room temperature and doesn't inter...Antibiotic Resistant Bacterium Uses Sonar-like Strategy to “See?Enemies or Prey
...first time, scientists have foundthat bacteria can use a Sonar-like system to spot other cells (eithernormal body cells or other bacteria) and target them for destruction.Reported in the December 24 issue of Science, this finding explains howsome bacteria know when to produce a toxin that makes infection...Molecular machine may lead to new drugs to combat human diseases
...les to cause biochemical reactions. Scientists can use this knowledge to manipulate the intron to splice ... of diseases, she said. Other scientists now will use the information gleaned from this study in an attempt to develop new drugs, Golden said. Introns we...Color-blind method opens new doors in DNA sequencing
... 'DNA sequencing' refers to the process scientists use to read out the order of those nucleotides. In sequencing, scientists first extract DNA from the nuclei of cells and through a painstaking series of bacterial cloning and/or polymerase chain reaction (PCR) steps, reduce its length to a manageable si...Female sex hormones play a vital role in defense against sexually transmitted diseases
...er of clinical studies as well show that women who use Depo-provera, a progesterone based injectable contraceptive, have particularly high susceptibility to sexually transmitted infections, including HIV-1 and HSV-2. We do not understand why, and our hope is that by doing these kind of mouse studies, we ...Spider Venom Could Yield Eco-Friendly Insecticides
...he mammalian nervous system, it may be possible to use them to create environmentally friendly insecticid.... The initial effectiveness of DDT in agricultural use and malaria eradication programs led many to view chemical insecticides as a panacea. But widespread...Gene variations explain drug dose required to control seizures
...approach when making decisions about which drug to use and in what dose," Goldstein said. "This study mak... then searched for an association between clinical use of the drugs and variation in the candidate genes. One variant of a gene known as CYP2C9, which enc...Solution to Pollution: New Bacteria Eats Toxic Waste
...through genomic analysis.?/p> Engineers often use other human-made chemicals to clean up contaminated sites, but these microbes will provide a natural solution, said Sims. Bioremediation cleans up the environment by allowing living organisms to degrade or transform hazardous organic contaminants usi...BRCA1 causes ovarian cancer through indirect, biochemical route
...ut interruption by pregnancy or oral contraceptive use are at highest risk for developing sporadic ovarian cancer," Dubeau explains. "So we had some clues that the cells that control the menstrual cycle-the ovarian granulosa cells-have an influence on ovarian cancer." But how? Was that influence direct,...