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Tag: "upon" at biology news

New lab technique churns out fungus' potential cancer fighter

...n fungi that selectively destroyed cells depending upon a gene called ras--one of the first known cancer-causing genes. They had found rasfonin, a compound that seemed tailor-made to knock out ras-dependent cancers like pancreatic cancer. After six years, however, rasfonin's secrets remain a mystery beca...

New lab technique churns out fungus' potential cancer fighter

...n fungi that selectively destroyed cells depending upon a gene called ras--one of the first known cancer-causing genes. They had found rasfonin, a compound that seemed tailor-made to knock out ras-dependent cancers like pancreatic cancer. After six years, however, rasfonin's secrets remain a mystery beca...

Chimpanzees can transmit cultural behavior to multiple 'generations'

...n of individual chimpanzees. These findings, based upon behavioral data gathered at the Yerkes Field Station in Lawrenceville, Ga., will publish online in the August 28 early edition of the Proceedings of the National Academy of Sciences. Using a research design that simulated transmission over multipl...

Mosquito spray increases toxicity of pyrethroids in creek, study finds

...ban streams, the researchers said. Based in part upon these prior findings, the California Department of...ces after a day or two," he said. However, based upon these study results, Weston said regulators should not only consider the toxicity of individual acti...

Scientist-astronaut sends T-cells into space

...mission on February 1, 2003, the Columbia broke up upon reentry into Earth's atmosphere, killing all seven crew members and destroying all experiments aboard. "We cannot go to Mars, or even to the Moon over the long term, without knowing more about why T-cells are not working," says Hughes-Fulford. "Wh...

COX-2 inhibitors significantly reduce risk of cancer

...er, case-control study of NSAID use and its impact upon the four leading types of cancer in the United Sta...hand, acetaminophen, which has a negligible effect upon COX-2 activity, and low-dose aspirin provided no significant change in the risk of breast cancer. ...

Predicting successful outcomes in living-donor liver transplants

...He concludes: "Before clinical decisions are based upon any of these tests, however, confirmation of the findings in larger patient populations in prospective studies are needed." ...

Weighting cancer drugs to make them hit tumors harder

...We can adjust the weight higher or lower depending upon where we want the drug to concentrate." Even drugs with vastly elevated molecular weights � 2 million molecular weight -- achieved better concentrations in tumors than a lower molecular weight, the study showed. Chilkoti said chemotherapy by itse...

Fruit fly reveals a potential connection between dementia and cancer

...d anticancer drugs. Cell-cycle activation depended upon a hyperactive cell growth molecule, TOR (target of rapamycin), also known to be abnormally activated in Alzheimer's disease. By establishing these causal connections, this study suggests that anticancer drugs are potential therapies for Alzheimer's d...

Paleontologists learn how not to become a fossil

... animal, like a shrimp, or they live parasitically upon the soft tissues of another organism. These guys have a lousy fossil record," Kidwell said. "If you're living inside the tissues, or directly attached to the tissues of another organism and it dies, then you're attached to a corpse of decaying organi...

Exotic crab poised for widespread UK invasion

...rs. Researchers from the University of Newcastle upon Tyne carried out the first comprehensive modelling of the crab's migration through Europe and the UK. They compared the two and found the pattern of the crabs' ongoing invasion of the UK is similar to the population expansion in Europe earlier in the...

Losing sleep undoes the rejuvenating effects new learning has on the brain

...verall, the study underlined that learning depends upon two things: exposure to novel material and getting a good night's sleep, Hairston said. Learning new things, at least in the case of spatial memory, quite literally keeps your brain young by ensuring a better survival rate for new brain cells in the...

Morning grogginess more debilitating than sleep deprivation, according to CU-Boulder study

...s and cognitive abilities during the groggy period upon awakening known as sleep inertia, said CU-Boulder ...ty and transportation workers who are often called upon to perform critical tasks immediately after waking, since cognitive deficiencies following 24 hours ...

Georgia Tech accelerates drug discovery with new IBM supercomputing cluster

...the world's 41st most powerful supercomputer based upon the November 2005 TOP500 list (www.top500.org) of supercomputers. The system performance and scalability will offer students and faculty the ability to quickly and accurately analyze complex DNA and proteins to determine the biological and chemical p...

Polymer aids in blood clotting, pointing way to new treatment

...und that polyphosphate was released from platelets upon stimulation, I immediately thought about a potential role in coagulation." In collaboration with Morrissey, an expert on blood clotting, Docampo and a team of U. of I. graduate and postdoctoral students tested the effect of adding polyphosphate to p...

USC, Rice to develop bacteria-powered fuel cells

...on of the genetic pathways that some microbes rely upon to maintain their respiratory metabolism in oxygen-poor environments. Shewanella oneidensis, one such bacterium, uses metals instead of oxygen to fully metabolize its food. "Since this organism is capable of passing electrons directly to solid metal...

Findings advance use of adult stem cells for replacement bone

...th-factor regime." In the study, Mikos's team hit upon the idea of having the stem cells create the proper growth medium themselves. The group, which included graduate student Quynh Pham and postdoctoral research associate Upma Sharma, accomplished this by seeding discs of titanium mesh with stem cells a...

Carbon cycle was already disrupted millions of years ago

...ssure in coal seams and then subsequently released upon coming into contact with magma. A third option is that carbon from organically-rich sediment came into contact with hot magma. As a result of this the organic molecules combusted into CO2 and water. Yvonne van Breugel's research was funded by NWO. ...

Researchers reveal lung's unique innate immune system

...pressed in its steady state, activated when called upon to fight invading microorganisms, and then re-repressed, in a circuit that is unique to this microenvironment. "Dissecting this immune mechanism provides us with the knowledge of how we might prolong the activation status of alveolar macrophages...

Molecule by molecule, new assay shows real-time gene activity

...nt understanding of this two-step pathway is built upon their averaging of genetic and biochemical activity across large populations of cells and molecules, masking the essential randomness of the process at the cellular level. Furthermore, much of our knowledge on the workings of the molecular machinery ...

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