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An entropy-based gene selection method for cancer classification using microarray data

...lied again to pare down the list of selected genes until a "minimal" subset is obtained that gives a satisfactory accuracy of classification. The algorithm was applied to three different data sets and the results obtained were compared to work done by others using the same data sets. This study presents a...

Jumping gene helps explain immune system's abilities

...ognizing a million immune-stimulatingproteins. But until now, no jumping gene was known to behave just right. Writingin the Dec. 23 issue of Nature, the researchers show that a jumpinggene called Hermes, still active in the common house fly, createschanges in DNA very much like those created by the proces...

UCSD Discovery Shows How Embryonic Stem Cells Perform 'Quality Control' Inspections

...ognizing a million immune-stimulatingproteins. But until now, no jumping gene was known to behave just right. Writingin the Dec. 23 issue of Nature, the researchers show that a jumpinggene called Hermes, still active in the common house fly, createschanges in DNA very much like those created by the proces...

New therapy for HIV/AIDS eliminates needles and excessive toxicity

...ognizing a million immune-stimulatingproteins. But until now, no jumping gene was known to behave just right. Writingin the Dec. 23 issue of Nature, the researchers show that a jumpinggene called Hermes, still active in the common house fly, createschanges in DNA very much like those created by the proces...

Gene sequencing explains bioremediation 'bug'

...ognizing a million immune-stimulatingproteins. But until now, no jumping gene was known to behave just right. Writingin the Dec. 23 issue of Nature, the researchers show that a jumpinggene called Hermes, still active in the common house fly, createschanges in DNA very much like those created by the proces...

Study Models Impact Of Anthrax Vaccine

...omepostal workers did not begin taking antibiotics until 9 days afterexposure.The current licensed anthrax vaccine requires six doses over an18-month period to provide immunity. The researchers looked at whatimpact a new and improved anthrax vaccine could have, and evaluated arange of vaccine characteristi...

Scientists discover that host cell lipids facilitate bacterial movement

...engthen, they drive the bacterium through the cell until it reaches the peripheral or outer cell membrane," explains Dr. Frederick Southwick of the University of Florida College of Medicine. "Here the growing actin filaments push the bacterium against the membrane, forming long membrane projections called ...

Sequencing of marine bacterium will help study of cell communication

...these signal molecules increase with cell density, until they initiate various reactions, such as light production ?or, in a pathogen, the release of toxin once a certain level of bacteria build up. Stevens studies the regulation system of the cell-to-cell communication. "Our quorum sensing research group...

Antibiotic might fight HIV-induced neurological problems

...-infected monkeys, but it is not expected to start until sometime next year. "It is too early to recommend minocycline for patients," emphasizes Ned Sacktor, M.D., an associate professor of neurology at the Johns Hopkins Bayview Medical Center who wasn't involved with the current study, but who is one of ...

Rats infected as newborns grew up vulnerable to memory problems during an immune challenge

... and those who were infected are completely normal until they get that second immune system challenge. The relatively uncommon one-two punch seems to cause the problem, although researchers don't know how long it lasts. Still, says Bilbo, "This may go far to explain some of the individual variability in di...

How the environment could be damaging men's reproductive health

...eriod, but clinically this is usually not detected until the third decade of life. Thus, the recent findings of good semen quality and low frequency of testicular cancer in Lithuania may reflect the intrauterine environment situation more than 20 years ago. However, cryptorchidism can be detected immediate...

Dead zone area in Gulf could be increasing, researchers say

...e Gulf of Mexico. "We saw no hypoxia in this area until June of last year, and this year we found in late March," DiMarco says. "If the physical conditions we noticed continue, it could mean an unusually strong hypoxic zone this year, and that's not good news." DiMarco said the team studied an area betw...

Nanoscale Diagnostic Sets Sights on Alzheimer's

...ADDLs would leak into the cerebrospinal fluid, but until now we couldn't detect them. Thanks to the extraordinary sensitivity of the BCA it's been possible to validate the prediction, and maybe even set the stage for creating the first clinical lab test for Alzheimer's disease. " -- William Klein, Northwes...

Low level of extinction during ice age linked to adaptability

...ction rates and did not re-appear in great numbers until the ice age ended. "The absence of these particular brachiopods during the ice age left the oceans populated almost entirely with those who lived over a wider geographic area," Powell said. "What I found is that the uniquely low global rates of evol...

50-year-old Mystery Solved: Protein Tags Regulate Key Ion Channel

...covered biological process known as sumoylation -- until now thought to be active only in the nucleus -- al...as an important mechanism of cellular activity but until now its 60-or-so known targets were primarily nuclear proteins, mostly involved in gene transcriptio...

New Drugs For Bad Bugs: UF Approach Could Bolster Antibiotic Arsenal

...dicine at the University of Wisconsin, adding that until now, “many, many antibiotics that initially came out have either had their dosages changed because they were excessive or had them increased because they weren’t enough.?/p>...

Researchers identify protein crucial for survival of Lyme-disease bacterium

...ted ticks fed, bacteria levels within them dropped until they eventually were zero. "We're not sure whethe...ok more in the tick," Dr. Norgard said. "It wasn't until we went through the later stages of tick feeding ?allowing the ticks to feed on mice, waiting a coup...

Gray wolves maintain the food chain in winter

...pus). Gray wolves inhabited most of North America until US extirpation campaigns nearly eradicated them by the 1930s. In 1995, the US Fish and Wildlife Service reintroduced the persecuted predator into Yellowstone. Wilmers and Getz used data from the past 50 years to establish winter trends and model wolv...

Rare surgery performed to remove pancreas, prevent diabetes

...following the surgery, and will be in the hospital until sometime next week, doctors said. Stewart's chron...uniformly good, so the procedure fell out of favor until recently, when new advances in cadaveric islet cell transplantation made outcomes more favorable. ...

Buying Time Through Hibernation on Demand

...y temperature taken down in order to buy them time until the pathology reports come back and they can get on the right course of treatment," Roth said. "Today, physicians have no way of dealing with uncontrolled fever other than literally putting people on ice. Well, we believe we know how to flip the brea...

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