Scientists discover dozens of new species in 'Lost World' of western New Guinea
... specimens collected by indigenous hunters from an unknown location on New Guinea, the species had been the focus of several subsequent expeditions that failed to find it. On the second day of the recent month-long expedition, amazed scientists watched as a male Berlepsch's bird of paradise performed a mati...MBL leads effort to update E. coli genome
...rchlight on the fraction of E. coli genes that are unknown and will accelerate laboratory work on the unknown functions with the goal of knowing what every gene does in the living organism," said Riley. Acco...Major WHO study concludes calcium supplements can reduce complications during pregnancy
...e. "Other simulations by our group discovered an unknown binding site on the integrase enzyme, " McCammon explained. "Merck's new anti-integrase inhibitors include molecules that are designed to hit that site, in addition to a site that was known earlier from x-ray crystallography studies." These new inhib...Computer simulation hints at new HIV drug target
...e. "Other simulations by our group discovered an unknown binding site on the integrase enzyme, " McCammon explained. "Merck's new anti-integrase inhibitors include molecules that are designed to hit that site, in addition to a site that was known earlier from x-ray crystallography studies." These new inhib...Study shows that cells have a natural defense against HIV
Scientists here have discovered a previously unknown mechanism that cells use to fight off the human immunodeficiency virus (HIV), the cause of AIDS. The findings indicate that two proteins that normally help repair cellular DNA can also destroy the DNA made by HIV after it enters a human cell. This ...Stanford/Packard scientist's data-mining technique strikes genetic gold
...t. Butte and Kohane identified several previously unknown correlations: nine genes whose expression increased or decreased significantly with aging, two genes that are highly expressed in response to injury, and another gene in which the expression drops significantly in leukemic cells. They also confirmed ...Hantavirus found in African wood mouse
...ease," the malady was later traced to a previously unknown hantavirus carried by the deer mouse. The team h... Africa, and they had the technology for detecting unknown hantaviruses. "We are also planning to look for other emerging viruses in our rodent collection," sa...Why nerve cells work faster than the theory allows
With accuracy unknown until now, researchers from the Max Planck Institute for Dynamics and Self-Organization and the Bernstein Center for Computational Neuroscience in Göttingen together with the neurophysiologist Maxim Volgushev from the Ruhr-Universität Bochum have ana...Diverse tropical forests defy metabolic ecology models
...eatened by global anthropogenic change, with still unknown implications for the integrity of their tremendous carbon stores. ...New RNAi tools enable systematic studies of gene function
.... This approach uncovered more than 100 previously unknown growth regulators in addition to several known players, confirming the library's sensitivity as a vehicle for gene discovery. "This critical new tool illustrates the requirement for academic and industry partnerships to drive scientific innovation,...Ocean virus identified in human blood samples
... of individuals with liver damage, or hepatitis of unknown cause related to blood exposure. A study on these...n viral infection and the presence of a disease of unknown cause does not prove cause and effect, the researchers say, but the data are intriguing and raise im...Mining for gems in the fungal genome
...dary metabolites," says Keller. For some as-yet unknown biological reason, all the genes required for the production of any given secondary metabolite-usually between three and two dozen genes-are located right next to each other along the chromosome in a gene cluster. These groups of genes stand out in ...Genes involved in cell growth and cell division identified
...rojects have revealed a large number of genes with unknown functions. The current study lead by professor Taipale identified a number of such functionally unannotated genes in addition to the identification of the majority of known growth regulators. This set of genes provides an excellent starting point for...Largest study of human 'interactome' reveals a novel way
...s allowed Pandey's group to identify 36 previously unknown protein-protein interactions, nine of which were tested in the laboratory to verify what the analysis suggested. "We proved they were valid," Pandey says. "By linking computerized sleuthing to laboratory experiments to confirm those findings, we exp...'Virus chip' detects new virus in prostate tumors
...egy of using the virus chip to discover previously unknown viruses and potentially uncover new viral causes for disease, the researchers say. While most other virus identification techniques require researchers to look for only a small number of candidates, the virus chip represents an unbiased search, since...UCSD study finds anthrax toxins also harmful to fruit flies
... that similar types of analyses might identify yet unknown proteins shared by flies and humans that can be ac...n of a variety of bacterial and viral pathogens of unknown function. One could then test hypotheses obtained from these studies with flies in mammalian organis...Genetic key to growth of new arteries is identified
...he researchers identified and described previously unknown areas of the MMP2 gene, plus other molecules that activate those areas, that are essential to expression of the gene in response to decreased blood flow. "It's a very time-consuming approach, but a very elegant way to deal with the problem," commen...Poison + water = hydrogen. New microbial genome shows how
...ull suite of genes for making spores, a previously unknown talent of the microbe. Organisms that make spores have attracted great interest recently because this is a process found in the bacterium that causes anthrax. Sporulation allows anthrax to be used as a bioweopon because the spores are resistant to ...Chlamydia parasite lives off our fat
... that Chlamydia use lipid droplets in a previously unknown pathway for lipid acquisition," says Kumar. "Alternatively, it is possible that the recruitment of lipid droplets constitutes an example of 'organelle mimicry' where Chlamydia escapes recognition by the host by cloaking itself in these fat-rich struc......planted in mice. Even though the idea is virtually unknown to cancer researchers today, many scientists worked on it in the 20th century. From the late 1960's up to today there have been many reports of tumor hybrids." "Aichel implored future scientists to study cancer cells 'from all angles' for evidence o...