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Tag: "understanding" at biology news

Development of portable infectious disease detector

...ts into itsmode of action."Pria has an outstanding understanding of the clinical and diagnosticdevice market and the ability to rapidly prototype optical andmicrofluidics devices," says Wikswo, "but it is difficult for thecompany to survey large numbers of possible applications. Yet, here atthe university, searchi...

Scientists discover unique microbe in California's largest lake

...layed a key rolein changing the scientific world's understanding of how ocean food websare based on much smaller organisms than previously believed.Wood is an adjunct scientist at the Bigelow Laboratory for OceanSciences and the Harbor Branch Oceanographic Institution. In 2004, shebecame a fellow of the Cooperativ...

Ice core 'dipstick' indicates West Antarctic ice has thinned less than believed

...ate in the last ice age and since, which is key to understanding how climate is changing today, Waddington said. "To make climate judgments based on the past requires knowing the past climate accurately," he said. ...

The Shapes Of Life: NIGMS Project Yields More Than 1,000 Protein Structures

...a lot of proteins that are incredibly important to understanding human biology and medicine, yet we know very little about most of them,?said Norvell. “The PSI will provide important information about these molecules so vital to life.?/p> The nine pilot centers participating in the first phase of the PSI are: ...

Beyond lithium for bipolar disorder

...treatments for bipolar disorder depend on a better understanding of the still-mysterious mechanism by which lithium damps the highs and lows of the disorder. Now, researchers led by Philip Brandish of Merck & Co., Inc., and Edward Scolnick of the Broad Institute (formerly of Merck and Co., Inc.) have identifie...

Duke Chemists Isolating Individual Molecules Of Toxic Protein In Alzheimer's, Parkinson's Disease

...olution of fibrils, They can thus develop a better understanding of amyloid aggregation. The scientists are also seeking the precise point during fibril formation when interactions between monomers become irreversible. Defining that point is important because "the fibrils are virtually indestructible once formed,...

Scientists identify new model Of NK cell development

...ses to cancer. "This study is fundamentally about understanding the immune system more fully so we can help patients," says Caligiuri. A major arm of the body's defense system is made up of lymphocytes, cells that fall broadly into three categories ?T cells, B cells and NK cells. Although all lymphocytes stem f...

White blood cell waste disposal system plays critical regulatory role

... actively linked to neutrophil production. A clear understanding of the processes that control neutrophil turnover may contribute to the development of future therapeutics for conditions characterized by abnormal numbers of these critical immune cells. Human neutrophils are white blood cells that are constantly b...

Research Using Mouse Models Reveals A Novel Key Player In The Initiation Of Colon Cancer

...ent. What is the significance of these results on understanding the initiation of colon cancer? A deficiency of Foxl1 in the mesenchymal layer of the colon leads to altered signaling to the epithelium layer and results in increased cell proliferation and turnover of this layer. In people with a genetic predisposi...

Agilent Technologies releases automated literature search tool for biology researchers

...p of complex biological networks, increasing their understanding of molecular pathways and the biological causes of disease. The Agilent Literature Search tool automatically searches for and extracts information from multiple textual databases, such as those of the U.S. Patent Office and the National Center for B...

New methods of gene delivery using lasers

...ch Council) which aims to use light to enhance our understanding of biology and to develop new biomedical devices. Although other research groups have touched on this area, the St Andrews group have greatly simplified the technique by using an extremely simple and versatile miniature violet laser which is compatib...

RNA project to create language for scientists worldwide

...NA science already is playing an important role in understanding normal and abnormal metabolism and physiology and in designing new strategies for intervention in the form of gene therapy, Leontis said. ...

Examination of internal 'wiring' of yeast, worm, and fly reveals conserved circuits

...ndispensable tools for biologists seeking a better understanding of all cellular functions. He said that just as a species evolved new proteins to give it a selective advantage, it also could have evolved a new combination of existing proteins. Such novel arrangements would have generated new capabilities or chang...

Unexpressed But Indispensable -- The DNA Sequences That Control Development

...ations drive development astray may lead to better understanding not only of these diseases, which are likely to be rare, but also of normal human development. ...

UF Researchers Map Bacterial Proteins That Cause Tooth Loss

.... “This study is important in that we now have an understanding of the protein expression on a global scale for this pathogen,?Lamont said. “Now we need to see how it adapts to various situations present in the mouth to cause disease.?/p>...

VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain

... suggest a 'network' of genes that may be a key to understanding drinking behaviors and the mechanisms of alcoholism." Other studies have suggested that interfering with Bdnf signaling can alter alcohol consumption. If researchers can identify drugs that may inhibit or activate the function of one of the genes i...

How an AIDS-Related Cancer Unleashes Inflammation

...w knowledge of kaposin B's role will contribute to understanding how the responsible virus produces cytokines, there are likely other mechanisms at work as well, Ganem emphasized. Other viral genes are also known to be involved in cytokine pathways, he said. Developing countries ?where HIV treatments are not read...

Sequencing of marine bacterium will help study of cell communication

... Virginia Tech is working to build a more complete understanding of the molecular processes that occur at the point that a bacterium changes its gene expression pattern in response to quorum sensing," she said. The genome sequence has allowed Stevens to begin exploring the connection between quorum sensing and oth...

Opposing fat metabolism pathways triggered by a single gene

...ther investigation of this link may lead to better understanding of the functions of PPARs and provide opportunities for altering their function for treatment of fat metabolism disorders such as diabetes and obesity. ### Citation: Van Gilst MR, Hadjivassiliou H, Jolly A, Yamamoto K (2005) Nuclear hormone recepto...

International HapMap consortium expands mapping effort

...is dream into reality. The payoff will be a better understanding of the genetic risk factors underlying a wide rang...e are 99.9 percent identical at the genetic level, understanding the one-tenth of one percent difference is important because it helps explain why one person may be ...

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