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Tag: "underlying" at biology news

Modeling the restless brain

...ture at multiple time scales that is shaped by the underlying structural topology," Sporns and Honey wrote in an article appearing this week in the Proceedings of the National Academy of Sciences early edition online. The article, which will be available at http://www.pnas.org/cgi/doi/10.1073/pnas.07015191...

Dirty snow may warm Arctic as much as greenhouse gases

...s in the snow have caused enough melting to expose underlying sea ice or soil that is significantly darker than the snow. The darker surfaces absorb sunlight more rapidly than snow, causing additional warming. This cycle causes temperatures in the polar regions to rise as much as 3 degrees Celsius during some s...

Brain holds clues to bipolar disorder

...The findings suggest a new avenue for treating the underlying cause of bipolar, rather than treating flare-ups of depression or mania, and also provide new targets, for improved medications many of which are being tested in clinical trials. Mary Phillips, M.D., professor of psychiatry at the University of Pi...

Breakthrough developments in rheumatoid arthritis reported

.... This will provide key insights into the pathways underlying rheumatoid arthritis and other autoimmune diseases. It may ultimately provide tests to predict who will respond to the available new treatments. Franak Batliwalla, PhD, also of The Feinstein Institute, will be presenting related studies on biomarker...

Researchers shed light on shrinking of chromosomes

...w hope to uncover the detailed molecular mechanism underlying the late shortening of chromosomes. This could further advance our understanding of cell division and the risk factors that lead to defects in chromosome separation and their dramatic consequences....

Penn researchers link cell's protein recycling systems

...because accumulation of toxic proteins is a common underlying feature of age-related neurodegeneration.” Taylor and his group study fruit flies in which the proteasome is disabled by a genetic mutation, which results in neurodegeneration. They use the fly eye, a neuron-rich tissue, as a surrogate for the br...

Putting feelings into words produces therapeutic effects in the brain

...ss meditation, and suggest, for the first time, an underlying reason why mindfulness meditation programs improve mood and health. “The right ventrolateral prefrontal cortex can turn down the emotional response you get when you feel angry,” he said. “This moves us forward in beginning to understand the benefi...

How brain pacemakers erase diseased messages

...pulses. A better understanding of the processes underlying deep brain stimulation could enable physicians to better fine-tune electrical implants, Grill said. That could be particularly useful for zeroing in on effective settings for implants used to treat diseases, such as epilepsy, in which seizures occur ...

Salk scientists hammer out a pathway that promotes muscle cell survival in mice

...zyme in muscle cells may someday shed light on the underlying mechanisms of many diseases that affect cell survival, such as muscular dystrophy, neurodegenerative diseases, and congestive heart failure." Montminy’s team, led by postdoctoral researcher Rebecca Berdeaux, Ph.D., first became interested in the ...

Gene malfunctions cause schizophrenia, depression symptoms in mice

... least in part, common genetic etiologies and thus underlying molecular mechanisms." ...

New technique will produce a better chromosome map

...ort out how the bands and interbands relate to the underlying genetic sequence, said cell and developmental biology research specialist Dmitri Novikov, who developed the new technique. The genome of the fruit fly, Drosophila melanogaster, was sequenced in 2000, and yet its relationship to chromosome structure r...

High-dose anticlotting drug cuts heart attack, death risk in half

... only. Further analysis showed that the higher the underlying risk of complications related to blood clotting, the greater the benefit from high-dose clopidogrel. The study will be presented at the Orlando SCAI meeting by Antonio Abbate, M.D., an assistant professor of medicine, Virginia Commonwealth Univer...

Asexual worm quickly adapts to soil contamination

... research disciplines are crucial for insight into underlying mechanisms of the response to stress and for the consequences for the natural system....

Brain maps online

...ying fine morphological and chemical abnormalities underlying Alzheimer's, Parkinson's and other neurological diseases, Mikula said. To make the maps, the researchers started with sections of brain mounted on microscope slides. Those slides were scanned to create image files or "virtual slides," and assembl...

Sandia researchers take new approach to studying how cells respond to pathogens

...gathered from a large population of cells may mask underlying mechanisms at the individual cell level. "Cells have different life cycles, just like any living being. And not all cells are exposed to the pathogen at the same time," Singh says. "We wanted to look at cells in the same life cycle and same infect...

Blood sugar's manufacture limited by building blocks' supply

...on." Gray said she plans to further explore the underlying mechanisms involved in KLF15's glucose regulation and see how increasing KLF15 levels affects blood sugar production. Meanwhile, Jain plans to further examine the transcription factor's function in other parts of the body where it is active, namely i...

Red flag for repetitive stress injuries identified for first time in humans

...by repetitive motions. These biomarkers warn of an underlying problem. "While not a diagnostic test, because ...lammatory mediators ?biomarkers ?which signaled an underlying problem," said Barr. "Also, the more severe the injury, the more biomarkers there were." Future r...

Scientists identify molecular cause for one form of deafness

...sts exploring the physics of hearing have found an underlying molecular cause for one form of deafness, and a co..., in principle, be made. "We have identified the underlying molecular cause for one form of deafness, and we have identified a mechanism to potentially 'rescue'...

Researchers identify gene involved in dog size

...s in dog size is particularly exciting because the underlying gene is present in all dogs and other diverse species, including humans,?said Eric Green, M.D., Ph.D., scientific director of the NHGRI Division of Intramural Research. “Discoveries like this illustrate the exciting promise of genomics research for u...

Major gene study uncovers secrets of leukemia

...identification of the genetic lesions that are the underlying cause of not only ALL, but also many other cancers, including those affecting adults," said James Downing, M.D., scientific director and chair of the Pathology department at St. Jude. He is senior author of the paper. The study found that 40 perc...

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