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Tag: "unaffected" at biology news

Mitochondrial DNA mutations play significant role in prostate cancer

...tpassed from father to son, but rather through the unaffected mother toher sons."...

Protein That Promotes Survival Of Stem Cells Might Be Key To Poor Leukemia Prognosis

...ntinued to flourish. In contrast, liver cells were unaffected following loss of Mcl-1, demonstrating that Mcl-1 is important only in certain cell types. Finally, the investigators showed that growth factors (natural proteins that stimulate cells to grow), such as the "stem cell factor," trigger the expression o...

15-year hunt finds cause of pseudothalidomide syndrome

...families (consisting of 18 affected members and 33 unaffected members) and tied the condition to one of 6 genes. Then, the international team compared the human sequence of the genes to those from chimpanzee, mouse, rat, chicken and zebrafish, and to the gene sequences of the affected family members. One segme...

Can our genes tell the story of our divergence?

...re functionally significant molecular changes than unaffected regions. In the new study, Rasmus Nielsen, Michele Cargill, and their colleagues compared 13,731 genes in humans to their equivalents in chimps to find positively selected genes in both species. Nielsen et al. identified many genes involved in senso...

TGen awarded $7.1 million to accelerate brain disease research

...tterns between an individual with a disease and an unaffected person. Using this information, investigators can identify the root causes responsible for certain disorders so that diagnostics and treatments can be developed that have a direct impact on the disease mechanisms. The Microarray Consortium initially...

Bird samples from Mongolia confirmed as H5N1 avian flu

...to put die-offs in perspective with the numbers of unaffected birds, thus there was no way to assess the impact. The WCS team at Erkhel Lake in Mongolia collected this information for the first time. Overall, over 6,500 apparently healthy birds of 55 species were observed on the lake. The percentage of sick...

Envisat and ERS-2 reveal hidden side of Hurricane Rita

...uable is that its C-band radar frequency is almost unaffected by heavy rain, so it can return useful wind data even from the heart of the fiercest storms ?and is the sole scatterometer of this type currently in orbit. The ERS-2 Scatterometer results for Hurricane Rita seen here have been processed by the Roya...

A little telomerase isn't enough

...osis congenita is a bone marrow transplant from an unaffected family member. But the team's new findings in mice suggest that the family member chosen for the transplant -- if there's more than one option -- should not only have normal telomerase levels but also have long telomeres compared to other family memb...

Role of microRNA identified in thyroid cancer

...her levels of expression in the tumors than in the unaffected tissue nearby. Further investigation revealed that two additional miRs ?miR-21 and miR-181a ?when coupled with the three that showed dramatic overexpression, formed a "signature" that clearly predicted the presence of malignant tissue. "We also d...

Spring migration of pink-footed geese under threat

...ns on the breeding grounds have generally remained unaffected by human activities, the staging and wintering grounds have undergone dramatic changes as a result of human development. As a result, most wintering populations have changed from feeding on natural or semi-natural habitats to agricultural land," Klaa...

Salmonella caught red-handed

...arrhoea and typhoid), the bacteria is surprisingly unaffected by the blockade of several central metabolic pathways. The reason for this is redundant enzymes, as well as the host offering a wide range of nutrients, which means Salmonella does not depend on its own biosynthetic abilities. Only a few enzymes in...

Losing sleep undoes the rejuvenating effects new learning has on the brain

...vantage of the specific neural substrates that are unaffected by sleep loss," the researchers concluded. "This finding could be used to design training regimens for chronically sleep-deprived people, including members of the military and medical students," Hairston said. "That said, while the cognitive impairm...

Key to early diagnosis of autism may be in the placenta

...acentas from 13 children with ASD to those from 61 unaffected children for the presence of trophoblast inclusions. They found that the placentas from ASD children were three times more likely to have the inclusions. Kliman and the team identified trophoblast inclusions by performing microscopic examinations o...

Can you hear me now? Scientists find previously unknown receptors on adult stem cells

...istence in a slumber-like state, unaware of -- and unaffected by -- the daily battles fought by the body's immune system. Not so. Scientists at the Oklahoma Medical Research Foundation have discovered that marrow stem cells -- undifferentiated cells that eventually give rise to the blood cells that fight infe...

New biologic treatment for tennis elbow may replace surgery for chronic sufferers

...n of the blood.) Blood was drawn from a patient's unaffected arm and spun down in the physician's office lab to separate the blood's components. Approximately a half-teaspoon (2 to 3 mL) of this material ?over 500% richer in platelets than whole blood ?was then injected into the tendon of the sore elbow. The...

Spike in testicular cancer is focus

...s with testicular cancer and in an equal number of unaffected control subjects. Because so little is known about the potential environmental causes of testicular cancer, Zheng said, the team will collect and evaluate information on various major suspected risk factors, such as past medical history, history of...

Walking not enough for significant exercise benefits

...ucose tolerance test and various blood lipids were unaffected by either exercise program. "Our concern is that people might think what matters most is the total number of daily steps accumulated, and not pay much attention to the pace or effort invested in taking those steps," Dr. Harber said. "The 10,000-step...

Vaccine for brain tumors shows promising results

...t. The vaccine is intended to leave healthy tissue unaffected and limit the debilitating side effects typically associated with traditional cancer treatments such as chemotherapy and radiation therapy. Vitespen has been granted fast track and orphan drug designations from the Food and Drug Administration in bot...

Edge density key to controlling gypsy moth spread

...ed that no pulsed expansion exists for populations unaffected by the Allee effect. However, when the it is a factor, not only does pulsed expansion occur, but it mimics the historic pulses of the gypsy moth population from 1960 to 2002 found in the quarantine records. Currently, the containment program for gy...

Origin of inherited pain disorder pinpointed

...rmed a detailed genetic comparison of affected and unaffected members of one large family that showed inheritance of the disease. That analysis revealed that mutations that compromise the gene for a component of one particular sodium channel, called SCN9A, were the likely culprit. Further analysis of the gene i...

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