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Tag: "ultimately" at biology news

Genomic Analysis Uncovers New Targets for HIV Vaccine

...ol the virus than others," Goldstein. "This should ultimately lead to novel targets for vaccines, the primary go... study. However, some of these polymorphisms could ultimately be shown to play a major role when future analyses involving more patients are performed, the resear...

Hormone helps mice 'hibernate,' survive starvation

...ating the PPAR-alpha-FGF21 signaling pathway might ultimately prove to be a vital part of the ongoing search for new therapies for human obesity and other metabolic conditions, Dr. Kliewer said. “Given that the PPAR-alpha receptor already is the target of drugs that work to boost high-density lipoproteins, o...

Research team identifies new Alzheimer's gene

...to provide a clearer picture of how life works and ultimately allow better clinical management of patients,” sai...capable of detecting the presence of GAB2, and may ultimately help millions of individuals reach a more informed decision regarding the most appropriate type and ...

Sun exposure early in life linked to specific skin cancer gene mutation

...om the initial phase of an ongoing study that will ultimately include more than 1,000 patients from the U.S. and Australia. The research was funded by the Dermatology Foundation, the National Cancer Institute and the UNC Lineberger Cancer Center. ...

Dual-imaging technique useful before -- and during -- brain surgery

...ze surgical approaches to treating brain tumors to ultimately improve patient outcomes.” He says that combining standard visual, sound, and voice-based tests, whose results are measured by MRI, performed on a high-field-strength (3 Tesla) scanner, with a precise intraoperative guidance system will improve p...

Breakthrough developments in rheumatoid arthritis reported

...d arthritis and other autoimmune diseases. It may ultimately provide tests to predict who will respond to the available new treatments. Franak Batliwalla, PhD, also of The Feinstein Institute, will be presenting related studies on biomarkers and genetic influences on drug response at the same meeting. I...

Now, self-healing materials can mimic human skin, healing again and again

...as two-part epoxies – to be exploited, which could ultimately lead to unlimited healing capability. “Currently, the material can heal cracks in the epoxy coating – analogous to small cuts in skin,” Sottos said. “The next step is to extend the design to where the network can heal ‘lacerations’ that extend into...

Cancer stem cells similar to normal stem cells can thwart anti-cancer agents

...stant tumor cells, called cancer stem cells, which ultimately become the source of disease recurrence and eventual metastasis. Now, research by scientists at the University of Pittsburgh School of Medicine suggests that for chemotherapy to be truly effective in treating lung cancers, for example, it must be abl...

Marine phytoplankton changes form to protect itself from different predators

... studying climate change because the predator that ultimately consumes the phytoplankton determines the fate of the carbon it contains. If eaten by copepods, for example, the carbon becomes part of fecal packages that sink into the deep ocean where a portion of that carbon is sequestered – thereby reducing atm...

Researchers discover 'acquired' DNA key to certain bacterial infection

...ium’s ability to enter environmental amoebas – and ultimately humans – is an “island” of genetic material acquired through evolution from another bacterium, according to Luiz E. Bermudez, a professor of biomedical sciences in OSU’s College of Veterinary Medicine and an author of the study. “Without these acq...

Fat fish put obesity on the hook

...derstand the molecular basis of disease. This may ultimately increase the efficiency and power of the drug discovery process, thus bringing new medicines to the market faster and cheaper.” In the study, researchers caused obesity in zebrafish by introducing the same type of genetic mutation that causes seve...

Study identifies 5 genetic themes key to keeping stem cells in a primitive, flexible state

...n dysregulated, they can lead to disease. This may ultimately allow us to develop targeted therapies to stimulate adult stem cells within our own bodies to repair damaged tissues, and may provide further areas of exploration for the treatment of cancer.”...

Scientists close in on missing carbon sink

...s in climate science has been the question of what ultimately happens to the carbon emitted by motor vehicles, factories, deforestation, and other sources. Of the approximately 8 billion tons of carbon emitted each year, about 40 percent accumulates in the atmosphere and about 30 percent is absorbed by the ocea...

Modified mushrooms may yield human drugs

...r. Romaine added. The degree of gene expression ultimately depends on where exactly the imported gene lands in the mushroom chromosome, among a complexity of other factors, but researchers point out that the process of producing biopharmaceuticals is potentially faster and cheaper with mushrooms than convent...

For many insects, winter survival is in the genes

...ese proteins, insects can't bear the cold and will ultimately die." Denlinger and his colleagues found nearly a dozen additional heat-shock proteins that are activated during diapause, a hibernation-like state that insects enter when temperatures drop. Insects can stay in this state of arrested development f...

UQ research heralds vaccine technology breakthrough

...es into the vaccine." He hoped the vaccine would ultimately be able to protect people against both diseases in the one shot and, even better, the recombinant vaccine model could potentially be used for most infectious diseases and some cancers, Professor Tindle said. Playing a key role in the research group...

Fat screen delivers plant-derived chemical with antidiabetic effects

...n inhibitor for a net positive effect on fat" that ultimately appears to restore insulin response without some of the side effects attributed to TZDs, Tontonoz said. The findings provide "a second example of a small molecule that both promotes fat cell differentiation in vitro and improves glucose tolerance ...

World's leading scientists announce creation of 'Encyclopedia of Life'

...lion from the Alfred P. Sloan Foundation, and will ultimately serve as a global beacon for biodiversity and cons...nserve biodiversity. The Encyclopedia of Life will ultimately make high-quality, well-organized information available on an unprecedented level. Even five years ...

The longest carbon nanotubes you've ever seen

...ricity than copper and many other materials--could ultimately find use in smart fabrics, sensors and a host of other applications. To grow the aligned bundles of tiny tubes, the researchers combined advantages of chemical vapor deposition (CVD), a technique for creating thin coatings that is especially commo...

DOE JGI sets 'gold standard' for metagenomic data analysis

...agments to enable the amplification, labeling, and ultimately sequencing. Genome assembly is the process of putting the sequenced fragments back in order, in effect, putting Humpty Dumpty back together again, to recreate the identity of an organism from the scattered puzzle pieces of DNA. "One of the probl...

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