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DNA-damage test could aid drug development

...als. "This research is the first stage in a new type of clinical drug toxicity test," says Lodish. "And although we haven't done it, you may be able to extend the technique to humans. Humans are the gold standard in that one wants an assay that directly predicts toxicity in humans, not animals, and you...

The quest for an effective HIV vaccine presents new possibilities, challenges

...s. Johnston and Fauci assert. Vaccines of this type present several complications, however. T-cell-mediated control of HIV infection may not stave off disease forever. Additional human studies would be needed to determine if the vaccine also reduces the spread of HIV. Finally, an HIV vaccine that dela...

Decoding protein structures helps illuminate cause of diabetes

...rted form of a human protein that is implicated in type II diabetes. Pancreatic damage in type II diabetes has been linked to toxic clumps of the protein hIAPP (human islet amyloid polypeptide), ...

Implanting dopamine generators in brain cells obtains improvement in Parkinson's in monkeys

...eriments and in humans. The advantage of this cell type with respect to others is the possibility of carrying out autoimplants, thus avoiding tissue rejection or immunosupressor treatment. Research Research was undertaken with monkeys who had Parkinson's induced by the administration of a neurotox...

Iowa State scientists demonstrate first use of nanotechnology to enter plant cells

...re swallowed by the plant protoplasts, which are a type of spherical plant cells without cell walls. Most plant transformation, however, occurs with the use of a gene gun, not through endocytosis. In order to use the gene gun to introduce the nanoparticles to walled plant cells, the chemists made anot...

A new portable biosensor detects traces of contaminants in food more quickly and cheaply

...ntibodies which hook onto, for example, a specific type of virus. Hence the virus is identified and may be eliminated. In the case of the sensors, specific antibodies for atrazine have been used (in the case of pesticides) and for sulphanilamide (in the case of identifying antibiotics). Once the antibodie...

Left-right wiring determined by neural communication in the embryonic worm

...y so that every worm still has exactly one of each type of cell," says the paper's senior author Cori Bargmann, Torsten N. Wiesel Professor and head of the Laboratory of Neural Circuits and Behavior at Rockefeller. "What is it that sets up this kind of handedness in the brain"" Prior studies had shown ...

Intelligent materials to regenerate bone tissue

...aused by accidents. The implants required for this type of solutions are more complex and sophisticated than the small implants known to date. . The Nanobiocom project aims at developing a support matrix (scaffold) of a compound material that is ‘intelligent? proactive, and capable of repairing and reg...

Bats get the munchies too!

...sweetness versus bitterness may vary according the type of sugar and the amount of ethanol consumed. The combination of sucrose and ethanol may just have tasted better than either ethanol and fructose, or ethanol and glucose?...

Switching genes to overdrive improves muscular dystrophy symptoms in mice

...chenne muscular dystrophy (DMD) is the most common type of muscular dystrophy in children, occurring once in about every 5,000 live births of boys, and is ultimately fatal. The average age of death is the mid-teens, and most patients die by their 30s. In the United States, about 400 to 600 boys are born e...

Biodegradable microspheres deliver time release vaccines, stimulate different immune response

...omething unexpected. The vaccine enhanced another type of immune response known as cellular-mediated immunity (CMI). CMI allows the immune system to identify, target and kill cells that have already become infected, something antibodies can not do. The determine the cause of this effect, Wilson-Welde...

Deconstructing brain wiring, one neuron at a time

... network, and even neighboring neurons of the same type differ in connectivity and function. So, resea...figure out the pattern of connections typical of a type of neuron, to see which other cell types they connect with and how those connections are configured....

MIT's ocean model captures diversity of underwater forests

...sholm, Follows and Dutkiewicz plan to use this new type of model to look in more detail at what shapes the habitats of the phytoplankton and to link this to other, larger scientific issues about oceans, the plants and creatures living in them and global climate. "This is just the beginning," said Chis...

It's never too late to get it back! Aging interrupted

...er of calories which are consumed, rather than the type of food which is the key to the effects of low calorie diets on the ageing process. However, it is known that vegetarians and fish eaters live longer than red meat eaters, and that, generally, the more fruit and vegetables in the diet, the better you...

Genome sequencing reveals key to viable ethanol production

..."Once we know how a bacterium targets a particular type of biomass, we should be able to boost that process to draw ethanol from biomass far more efficiently that we can today." Ethanol holds the promise of a clean, renewable alternative to fossil fuels, but deriving it from plants is difficult. Produci...

Rare cell prevents rampant brain activity

...n excitatory signals, which are transmitted by one type of synapse, and inhibitory counter-signals, which ...a mechanism that might explain how the most common type of neuron in the cerebral cortex ?the pyramid cell ?is prevented from becoming over-activated. Their...

Investigating the measles virus as a tool to kill multiple myeloma

...d or refractory (that is, having had more than one type of treatment fail them) myeloma. They must not have had allogeneic (from another person) stem cell transplants and must either have had a prior measles infection or been vaccinated against it. In the 1970s, measles infections were observed to cau...

Scientists identify pancreatic cancer stem cells

... The researchers then implanted about 100 of each type of cell in mice, and found that tumors would grow in a subset of the animals, but cells that expressed all three markers were the most potent, producing tumors in six of 12 mice tested. If more cells are used, "we can get tumors to grow 100 percent o...

Stanford-led study closes in on genes that may predispose some people to severe depression

...ression, then we would be able to understand what type of gene is it, what it does in the brain and by what mechanism it could make one more or less predisposed to depression." Knowing more about which genes are the major factors causing a predisposition for depression would also help researchers ...

Sandia researchers take new approach to studying how cells respond to pathogens

...cells are short-lived outside of bodies. To do the type of experiments they wanted, the researchers needed cells that can stay alive more than a couple of hours, have the ability grow and represent a relevant model of human immune cells. They obtained "immortalized mouse immune cells" from a collaborator ...

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(Date:12/3/2009)...eve that staph infections are caused by many bacte...The signaling process is called quorum sensing bec...ocess. , But the Jeff Brinker research group has...ection, when bacteria switch from a harmless to a ...is individual process can be stopped by the applic...
(Date:12/3/2009)...evels for the past three years in the troposphere ... area near Valladolid. The results, which are the ... that the levels rose "significantly" between 2002...eteorologists have been trying to find out about c...lved in the troposphere over various urban and rur...
(Date:12/2/2009)...o men have a more difficult time quitting smoking ...re, but acculturation has no affect on Latinas odd...re published in Cancer Epidemiology, Biomarkers &...n for Cancer Research. The December issue has a sp... smoking cessation differently for Latino men and ...
Breaking Biology News(10 mins):Stopping MRSA before it becomes dangerous is possible, Sandia/UNM researchers find 2Stopping MRSA before it becomes dangerous is possible, Sandia/UNM researchers find 3CO2 levels rising in troposphere over rural areas 2Acculturation affects smoking cessation success among Latinos 2Cradle and birthday of dog identified 9751 1Hard To Treat Diseases 28HTDS PK 29 Stem Cells and Regenerative Medicine 4931 1Hard To Treat Diseases 28HTDS PK 29 Stem Cells and Regenerative Medicine 4931 2Hard To Treat Diseases 28HTDS PK 29 Stem Cells and Regenerative Medicine 4931 3Video 3A New Insights Link Low HDL Cholesterol and Elevated Triglycerides with Coronary Heart Disease and Microvascular Complications in Patients at G 55865 1Video 3A New Insights Link Low HDL Cholesterol and Elevated Triglycerides with Coronary Heart Disease and Microvascular Complications in Patients at G 55865 2Video 3A New Insights Link Low HDL Cholesterol and Elevated Triglycerides with Coronary Heart Disease and Microvascular Complications in Patients at G 55865 3Video 3A New Insights Link Low HDL Cholesterol and Elevated Triglycerides with Coronary Heart Disease and Microvascular Complications in Patients at G 55865 4Video 3A New Insights Link Low HDL Cholesterol and Elevated Triglycerides with Coronary Heart Disease and Microvascular Complications in Patients at G 55865 5Video 3A New Insights Link Low HDL Cholesterol and Elevated Triglycerides with Coronary Heart Disease and Microvascular Complications in Patients at G 55865 6Video 3A New Insights Link Low HDL Cholesterol and Elevated Triglycerides with Coronary Heart Disease and Microvascular Complications in Patients at G 55865 7Video 3A New Insights Link Low HDL Cholesterol and Elevated Triglycerides with Coronary Heart Disease and Microvascular Complications in Patients at G 55865 8
(Date:12/4/2009)..., LOS ANGELES, Dec. 4 Yogen Fruz ...announced today the launch of its holiday themed "...n December 7, the new festive mixes will be unveil...n Fruz,s low-calorie Yog-Nog and Mint Chocolate Ch...rt alternative to indulge in this holiday season. ...
(Date:12/4/2009)... , BOSTON and HOUSTON, Dec. 4 /PRNewswire-F...eronics, Inc . (Nasdaq: CYBX ) announced today th...ly FDA-approved implantable medical device for the...d in 14 presentations at the American Epilepsy So...er 4-8 at the Hynes Convention Center in Boston, M...
(Date:12/4/2009)... InhibOx, a leading developer of n...discovery, has joined forces with MolPort, an inno... developing rare chemical trading platform and bui...Now we provide this database and its updates to co...rate it into the virtual screening procedures. Onc...
(Date:12/4/2009)... IntelliSoft Group offers their new...r in medical credentialing software, IntelliSoft G...e as a Service) deployment option. ,SaaS is an exc...t have budget restraints, yet are in need of medic... (Vocus) December 4, 2009 -- ISG Group, LLC, do...
(Date:12/4/2009)... Best-Selling author and Personal &...ss Organizational Transformation through Accountab... (PRWEB) December 4, 2009 -- IMPAQ Accountabilit...t Mark Samuel , best-selling Author, renowned Spe...y Business Consultants Inc., will present at the 1...
Breaking Medicine News(10 mins):Health News:Yogen Fruz Introduces New Holiday Flavors: Yog-Nog and Mint Chocolate Chip 2Health News:NYU Langone Medical Center Study Shows VNS Therapy is a Safe and Effective Treatment for Refractory Epilepsy 2Health News:NYU Langone Medical Center Study Shows VNS Therapy is a Safe and Effective Treatment for Refractory Epilepsy 3Health News:InhibOx and Molport Join Forces to Deliver Integrated Lead Design and Delivery 2Health News:InhibOx and Molport Join Forces to Deliver Integrated Lead Design and Delivery 3Health News:IntelliSoft Group Focuses on Protecting Customer Investment in Medical Credentialing Systems -- Budget Constraints and Forced Upgrades in Medical Credentialing Automation 2Health News:Mark Samuel, CEO & Founder, IMPAQ Accountability Business Consultants Inc., to Present at 14th ICF Annual International Conference 2
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