Ice Age extinction claimed highly carnivorous Alaskan wolves
...tively unscathed. But this previously unrecognized type of wolf appears to have vanished without a trace some 12,000 years ago. The study, which will be published in the June 21 online issue of Current Biology, combined genetic and chemical analyses with more conventional paleontological study of the m...New vaccine prevents CMV infection and disease in mice
...egalovirus (hCMV) infection and disease. CMV, a type of herpes virus, is the leading viral cause of birth defects and a serious problem in patients with compromised immune systems. The body’s natural immunity doesn’t protect against infection by the virus, estimated to be present in 50 to 75 percent o...Adult stem cells from human cord umbilical cord blood successfully engineered to make insulin
...a fundamental discovery that someday may help cure type 1 diabetes by allowing people to grow their own i...f cells, Denner explained. Then, for a person with type 1 diabetes, researchers might engineer these cells to become islets of Langerhans, the cellular mass...HIV and malaria combine to adversely affect pregnant women and their infants
...ed that protection to PAM is mediated by a special type of antibody that allows women to preferentially clear the parasites in their placentas. They found that HIV-infected women lose these antibodies and again become susceptible to the ravages of PAM. The findings, according to Kain, may help in the d...Mice with a migraine show signs of brain damage
...d from migraines were much more likely to have the type of brain damage done by a stroke, even though they had never reported symptoms of stroke. Friedman, a member of the board of directors of the American Headache Society who has treated thousands of headache sufferers, echoes Nedergaard’s call for a...Scripps research team sheds light on long-sought cold sensation gene
...me cold, as evidenced by responses similar to wild type mice when exposed to -1° C cold plates. This suggests that other genes are responsible for this facet of cold sensation. Though cold can be unpleasant or painful under certain circumstances, it can also deaden pain, as illustrated by icing an inju...'Insulator' helps silence genes in dormant herpes virus
...as interacting with other viral proteins to form a type of insulator in the virus structure," Zhou says. To verify that it was an insulator at work, the researchers then inserted copies of the structure into fruit fly embryos to see if they could block the activity driven by gene-activating elements c...Keeping the immune system from starting a 'food fight'
...including insulin resistance, fatty liver disease, type 2 diabetes, and cardiovascular disease. This cluster of chronic diseases now constitutes the largest global health threat, Hotamisligil said. Their current findings pinpoint STAMP2 as a critical factor to prevent overt inflammatory responses durin...First clinical trial of gene therapy for childhood blindness
...led Leber’s congenital amaurosis (LCA), which is a type of inherited retinal degeneration. This disease causes progressive deterioration in vision, due to an abnormality in a particular gene called RPE65. This defect prevents normal function of the retina, the light-sensitive layer of cells at the back of...8 plants from South Africa may hold potential for treating high blood pressure
...ar, provide beneficial properties to patients with type 1 diabetes. In an effort to identify indigenous plants consumed by the local population in Kwa-Zulu Natal that hold potential antihypertensive properties, the researchers examined 16 plants to identify ACE inhibitor activity. The plants were: ...UQ research heralds vaccine technology breakthrough
...g with helping children, it included forming a new type of vaccine. The research group has developed a "recombinant" vaccine using the existing Hepatitis B vaccine to carry the RSV peptides. "Hepatitis B surface antigen forms virus-like particles, which are the vaccine used for Hepatitis B vaccine all a...Gene mutation linked to cognition is found only in humans
...es and monkeys. Their previous work had shown that type II neuropsin, a longer form of the protein, is not...n the current study, they tested the expression of type II in the PFC of two great ape species, chimpanzees and orangutans, and found that it was not presen...Risk of lymphoma increases with hepatitis C virus infection
...developing Waldenström's macroglobulinemia (a rare type of non-Hodgkin's lymphoma) went up by 300 percent ... that 71,380 Americans will be diagnosed with some type of lymphoma, which will take 19,730 lives. The researchers note that this study was limited to mi...Molecule that destroys bone also protects it, new research shows
...t a sea change in 2005 with the discovery of a new type of T cell that produces IL-17, now called TH-17," she said. "We know now that almost all autoimmune diseases, at least in the mouse model, are caused by TH-17 cells. This new information has forced scientists to revise completely how they view their ...Survival of the rarest: Fruit flies shed light on the evolution of behavior
...ators. However, to date we haven't understood this type of survival advantage at the level of the gene." ...al of the other. In essence, there is not one best type of fly," he says. If this process is common in nature, it may offer one explanation for why individu...Researchers publish first marsupial genome sequence
... ultraviolet radiation alone can cause melanoma, a type of skin cancer that also strikes humans exposed to too much of the sun's ultraviolet rays. Having the sequence of the opossum genome will give researchers the ability to learn more about the molecular basis of melanoma and its progression, as well as...Study shows continued success for new HPV vaccine against virus responsible for cervical cancer
...nd treat these pre-cancerous stages caused by some type of HPV." To date there is no vaccine specifically designed to treat disease that is already established. Dr. Ault explains the current HPV vaccine is meant to be a preventive or prophylactic vaccine Ð that's why it is given to adolescents. Gar...Tissue engineered scaffolding allows reproduction of cartilage tissue
... the shape and porosity can be altered to suit the type of tissue required." ...Study offers clues to 'Broken Heart Syndrome'
...ercent were women, and 60 percent experienced some type of stress shortly before coming to the emergency room. The intensity of the stress varied dramatically, however, ranging from armed robbery to a heated argument, tooth extraction, or preparation for a colonoscopy. "We don't know why some women de...High-dose anticlotting drug cuts heart attack, death risk in half
...ly dose (75 mg) for up to a year, depending on the type of stent used to prop open the clogged coronary artery. To evaluate the effect of the clopidogrel loading dose, researchers from University of Turin and Virginia Commonwealth University, in Richmond, performed a meta-analysis of data from 10 studi...