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Tag: "turned" at biology news

Depression gene may weaken mood-regulating circuit

...ight this gene account for it?'" In this case, it turned out that the amygdala, a fear processing hub deep in the brain and the cingulate, an emotion-dampening center located near the front of the brain, were playing a duet under the baton of the depression-linked gene. The gene codes for the serotonin tr...

Proteomics brings researchers closer to understanding microbes that produce acid mine drainage

.... To identify the peptides from their masses, they turned back to the genomes. The genomes they obtained last year allowed them to predict the proteins in each member of the biofilm community, and from that predict the protein fragments that would result if they were all chopped up. Correlating the two allo...

Bees, Brains and Addiction

...t lead to addiction, some researchers at UCSD have turned to bees. Granted, the brains of humans and bees don't look much alike. But how bees respond to simple rewards, such as food, can tell scientists much about the workings of the primitive portion of our brains that lead some of us to become addicted t...

Identification of specific genes predicts which patients will respond to Hepatitis C treatment

...as the level of expression ?whether the genes were turned on or turned off - of 18 genes. "Our results demonstrate that a relatively small number of genes can predict res...

TGen awarded $7.1 million to accelerate brain disease research

...nologies which provide information about the genes turned on or off in the diseased tissues being studied. Scientists use these microarray technologies to compare genetic patterns between an individual with a disease and an unaffected person. Using this information, investigators can identify the root cause...

Microscopic brain imaging in the palm of your hand

...t at the deep structures, the Stanford researchers turned to microendoscopy, tiny, minimally invasive optical probes that could be inserted deep into living brain tissue. To make one group of images (figures 1c-1e), the researchers inserted the microendoscope into the hippocampus, about a millimeter below t...

Fragment of yellow fever virus may hold key to safer vaccine

...sary components of an improved vaccine, ter Meulen turned to survivors of acute yellow fever in the Republic of Guinea in West Africa. Along the war-torn border with Sierra Leone, disruptions in vaccination and medical services led to a large epidemic in 2000. In collaboration with local health authorities,...

Snapin: A protein with therapy potential for autism

...drite skeleton. Now Firestein's research group has turned its attention to the protein snapin. When snapin binds to cypin, tubulin is crowded out, so fewer dendrites assemble and more branching occurs. When researchers overexpressed snapin in hippocampal neurons in the lab, the number of primary dendrites ...

Say what? Bacterial conversation stoppers

...n the test tube, AI-2 production by either species turned up the marine bacteria's light and turned on the quorum-sensing genes in E. coli. That confirmed what the scientists already suspected: the...

Study casts doubt on 'Snowball Earth' theory

...iques to previously unexamined rock formations has turned up strong evidence on the "Slushball Earth" side of a decades-long scientific argument. The study appears in the Sept. 29 Science Express. The lead author is Alison Olcott, a Ph.D. student of earth sciences in the USC College of Letters, Arts and Sc...

Stem Cells Found In Cerebellum; Possible Cell of Origin for Childhood Brain Tumors

...minating cells. But upon closer examination, these turned out to include a small population of neural stem cells, said Audra Lee, a research associate in Wechsler-Reya's lab who carried out the majority of the work. The stem cells they isolated represented less than one percent of the total number of cells...

Compound from Chinese medicine shows promise in head and neck cancer

...ells became sensitive to cisplatin when Bcl-xL was turned off, confirming its role in drug resistance. "We believe novel agents that target Bcl-xL can improve survival for our patients," Carey says. In a previous study published in November 2004 in Clinical Cancer Research, Bradford, Carey and their team ...

Scientists devise way to measure RNA synthesis on the fly in a live cell

...a major role in determining when and how genes are turned on and off, but they have lacked the ability to monitor action of these molecules as it happens within a single living cell. Now Cluzel and his associates, using a technique called fluorescence correlation spectroscopy (FCS), have shown how to monit...

Gene therapy to lower blood pressure just enough

...duce disease connected to a gene regulatory system turned on by the drug mifepristone. Using this vector, O...ne into the cells of mice. Then tiny doses of drug turned on the regulatory system, which controlled the amount of ANP made so that blood pressure remained at...

Chemical 'band-aid' prevents heart failure in mice with muscular dystrophy

...the level of individual heart muscle cells, and it turned out to be true at the organ level, also." The key to the U-M discovery was technology developed by Soichiro Yasuda, Ph.D., a post-doctoral fellow and co-first author of the study. He created a device to allow the simultaneous measurement of force an...

Mayan stingless bee keeping: Going, going, gone?

...echnology is all but lost, but we'd like to see it turned around, not only to ensure the survival of meliponiculture as a way of life, but also to build up breeding stock to be re-introduced into the wild where bees play an important role as pollinators," Roubik explains. But beekeeping is fast becoming a ...

MicroRNA tweaks protein that controls early heart development

... protein synthesis can immediately be shut off and turned back on based on a cell's environment or its needs at the time." Dr. Yong Zhao, a postdoctoral researcher in Dr. Srivastava's lab at UT Southwestern, developed a new method to predict targets for vertebrate microRNAs based on the genetic sequence of...

U of MN researchers reverse memory loss in mice

...hat when the transgene expressing the dementia was turned off, memory loss would stop. The results, however, surpassed their expectations. The mice's symptoms of dementia were reversed--in other words, they regained memory. "Most Alzheimer's disease treatments focus on slowing the symptoms or preventing th...

Energy management in cells may hold key to cancer defense

...around and alter any deficits in the cell if it is turned on by the kinase LKB1. In this JBC study, we wanted to see if AMPK could also be turned on by something besides LKB1." "We decided to work with cervical and lung cancer cells because LKB1...

Mechanism regulating tooth shape formulation found

...o be a recently identified gene called ectodin. It turned out that ectodin is the first gene that is expressed as a mirror image of the future cusps. The team generated a mouse that has no functional ectodin. Whereas the mice appear fairly normal, the areas forming cusps were much broader resulting in che...

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