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Tag: "turned" at biology news

Scientists document complex genomic events leading to the birth of new genes

...single copy in all other species tested. They then turned their attention to the gene that exhibited the most dramatic of these duplications: RanBP2. RanBP2 is the largest protein found at the nuclear pore complex, helping to regulate nucleic acid and protein traffic in and out of the nucleus. The correspon...

Ice core 'dipstick' indicates West Antarctic ice has thinned less than believed

...f the site where snow was deposited and eventually turned to glacial ice, the work gives scientists new information for interpreting climate in the last ice age and since, which is key to understanding how climate is changing today, Waddington said. "To make climate judgments based on the past requires kno...

First real-time view of developing neurons reveals surprises, say Stanford researchers

...ed left to right, a distinct population of neurons turned fluorescent colors to indicate their activity. Moving the square the reverse direction triggered a different population of neurons to light up. "At first we felt like we let some air out of our own tires with this finding," said Smith. His previous ...

Newly Discovered Compound Blocks Known Cancer-Causing Protein

...ayer in keeping a cancer-causing gene called 'Ras' turned on inside cells," said Casey. Ras is a normal gen...cal structure. A search of the chemical literature turned up no previous description of the chemical, leading the scientists to believe they had discovered a ...

VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain

... some cases exposure to alcohol caused genes to be turned on more in one strain while decreasing expression of the same gene in the other mouse strain. Such differences are thought to be related to the mechanisms underlying the different behaviors that the B6 and D2 mice show with alcohol. Researchers also...

Asthma gene clusters identified

... of the disease. "Now that we know what genes are turned on during an asthma attack, we will conduct studies to see if this genetic profile can be used to customize care. The current methods of treatment primarily consist of anti-inflammatory drugs, which may not be optimal for acute attacks," Dr. Hershey ...

LUCA technologies confirms real-time methane generation

... currently active but may have the potential to be turned into active Geobioreactors through cross-inoculation with microbial consortia from active sites. Luca scientists have also begun to isolate and identify particular members of the Monument Butte microbial consortium. Through partial DNA sequence anal...

Molecular Motors Cooperate In Moving Cellular Cargo, Study Shows

...t appears that motors are somehow regulated, being turned on or off in a fashion that prevents them from simultaneously dragging the peroxisome." In the future, Selvin wants to combine FIONA and an optical trap technique to monitor the speed and direction of a peroxisome, and the force acting upon it. "By...

Variation in women's X chromosomes may explain differences among individuals, between sexes

...471 genes to determine whether the second copy was turned on or off. Overall, about 15 percent of genes on the second X chromosome escape inactivation to some degree, they found. The proportion of genes that remain active differs dramatically among regions of the X chromosome, they reported. Furthermore, ...

New component of the 'brakes' on nerve regeneration found

...lex is known to function. The two research groups turned their attention to TAJ/TROY because it is a member of the same family of receptor proteins--called TNF receptors--as p75. Their experiments revealed that TAJ/TROY is produced throughout the adult brains of mice. Also, they found that TAJ/TROY readily...

Gene therapy promising for growing tooth-supporting bone

...obile said using a virus, with the harmful effects turned off, harnesses the virus' ability to enter into cells and use their genetic machinery. Once inside the cell, the viruses help BMP-7 genes get where they need to be in the host's cells to boost bone production. Gene expression producing BMP-7 protein...

Promising new West Nile therapy cures disease in mice

...dious molecular-level screening process. They then turned to Rockville, MD-based MacroGenics Inc., to create a human-like version of the most effective antibody. MacroGenics stitched the part of the antibody that cripples the West Nile virus into the scaffold of a human antibody. The monoclonal antibody was...

Survey finds silver contamination in North Pacific waters

...lver contamination ever observed in the open ocean turned up in samples collected during a survey of the North Pacific in 2002. Researchers from the University of California, Santa Cruz, measured silver concentrations 50 times greater than the natural background level. Though still well below levels that wo...

Scientists identify genetic pathways essential to RNA interference

...the worms to glow under ultraviolet light but also turned that gene off using RNAi. They then used RNAi to inactivate every one of the worms' 19,000 genes by feeding the worms bacteria that produce double-stranded RNA for each gene. Inactivation of about 90 genes caused the worms to glow, indicating that th...

Brain Scans Reveal How Gene May Boost Schizophrenia Risk

...radio. For the clearest signal, the "dial" must be turned in opposite directions, depending on which version...rontal and too much midbrain dopamine, the dial is turned "way up," the NIMH researchers speculate. "We expected that there would be different regulatory mec...

Study: 'homemade' gene expression technology unreliable

...etermine how the expression of individual genes is turned up or down by placing copies of DNA or RNA molecules labeled with fluorescent dyes on the slide, and examining whether the molecules that bind to a particular gene light up when viewed with a special scanner. By interrogating thousands of genes at o...

New tumor-suppressor gene discovered

...f a known tumor-suppressor gene named "wts," which turned out to be the case. The researchers performed three experiments to test whether the mats and wts genes interact genetically. In the first experiment, they inserted an additional normal mats gene into a line of flies and found no change in the shape ...

Protein helps regulate the genes of embryonic stem cells

... associated with modified histones is marked to be turned on or off. In the study, eed is the first protein shown to be required for the addition of a single methyl group to histone H3, said Montgomery. Knowing which proteins are responsible for the various histone modifications is the first step toward un...

Biochemists report discovery of structure of major piece of telomerase; implications for cancer

...o longer divide, and they die. While telomerase is turned off in most types of healthy cells in our bodies, it is active in the vast majority of cancer cells, Feigon said. Because cancer cells divide rapidly, their telomeres should get shorter more quickly than normal cells. However, because cancer cells h...

One gene links newborn neurons with those that die in diseases such as Alzheimer's

...b to find out which of the genes in the cells were turned on. This technique allowed them to identify which ... in the replaceable neurons. But instead, one gene turned up in consistently low levels. The gene was UCHL1. "We expected UCHL1 would be high in all kinds o...

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