tumors 2 9

Tag: "tumors" at biology news

Common molecular 'signature' identified in solid tumors

...g, breast, stomach, prostate, colon and pancreatic tumors and in the normal tissue surrounding them. Using microarray technology developed at Ohio State , lead investigators Stefano Volinia and George Calin found 137 different miRNAs expressed in at least half of the cancers, with 43 miRNAs allowing scien...

Proteins stop blood-vessel and tumor growth in mice

...own as fibulins 3 and 5, slow the growth of cancer tumors in mice by preventing blood vessels from sprouting... cancer-related death. Fighting cancer by starving tumors of life-giving blood vessels has generated great interest in recent years. In their most recent exp...

Protein found to control tumor growth in certain breast cancers

...ellular model for estrogen sensitive breast cancer tumors ?were used to induce tumor growth in severe combin...ses in vitro. Moreover, scientists found that the tumors diminished rapidly in these mice, becoming virtually undetectable by the end of the experiment. I...

Newly discovered killer cell fights cancer

...actor combo served as a lure, leading the IKDCs to tumors implanted in the mice. The results were that tumors shrunk in mice, which received injections of IKDCs, but not in those receiving conventional NK cells...

VCU Massey Cancer Center researchers identify a new class of anti-cancer drugs based on platinum

...esistance and side effects and expand the range of tumors that can be treated by platinum. In the Dec. 26 issue of the journal Inorganic Chemistry researchers reported on the design of a new trinuclear platinum compound and demonstrated that its cellular absorption is significantly greater than that of neu...

Stem cell transplants improve recovery in animal models for stroke, cerebral palsy

... cells have been shown to be safe, and do not form tumors or other abnormal tissue, a potential problem seen with embryonic stem cells. Furthermore, MultiStem TM cells generally do not require the close genetic matching between donor and recipient that is needed for a bone marrow or conventional stem cell...

Molecular force field helps cancer cells defend against attack

...uman tumors, and our work has shown this makes the tumors more likely to survive as they spread throughout t...colleagues were the first to pull FAK out of human tumors and to show that human cancers make the molecule in large quantities. In 1996, the team was the firs...

New Research Shows Artificial Light at Night Stimulates Breast Cancer Growth in Laboratory Mice

...ficial light stimulated the growth of human breast tumors by suppressing the levels of a key hormone called ...velopment of cancerous tumors. “We know that many tumors are largely dependent on a nutrient called linoleic acid, an essential fatty acid, in order to grow,...

Nano-particles effective in killing cancer with one-two punch of chemotherapeutics

...d names such as Taxol, and doxorubicin directly to tumors implanted in mice. Their findings, presented online in the journal Molecular Pharamaceutics, illustrate the broad clinical potential of polymersomes. "The system provides a number of advantages over other Trojan horse-style drug delivery system,...

Loosen leash on cancer protein 'watchdog,' researchers say

... the ability to halt the progression of intestinal tumors that arise from genetic predisposition. When the activity of this protein, known only by the technical name of p53, was artificially increased in the cells of laboratory mice, those known to have a hereditary predisposition for developing cancer show...

'Shuttling' protein possibly key to resilience of cancer cells

...stance role of cancer stem cells could explain why tumors return after treatment. If stem cells prove to be critical to cancer's resistance to treatment, new medications might be developed to target cancer stem cells while chemotherapy or radiation is administered, Hu said. Research findings are detailed i...

Tumor cells that border normal tissue are told to leave

...ng the cancer cells to establish deadly metastatic tumors elsewhere in the body. The researchers say their... tissues." To do this, the research team created tumors in fruit fly eyes and wings that permitted them to study the behavior of individual tumor cells. "...

New test to detect rare proteins in blood

...n these cells are implanted into animals they form tumors exactly like breast tumors in humans. Using ELISA, the researchers could not detect Her2/neu from mouse blood until the tumors ...

How can we protect patients with weakened immune systems from influenza?

...ng different intensities of chemotherapy for solid tumors and two types of leukemia. Another project is dedicated to children with neuroblastoma, a solid tumor of the peripheral nervous system, who are treated with a novel type of stem cell transplant. Both chemotherapy and stem cell transplants involve sup...

Scientists discover a genetic switch that links animal growth and cancer

...and proliferation of cells during the formation of tumors in cancer, it also involves the same players," said Rothman. The research team found that PTEN functions with two other proteins –?known as protein kinases –?that are also involved in cancer progression. This discovery means that other proteins that...

Curry and cauliflower could halt prostate cancer

...ells from human prostate cancer cell lines to grow tumors against which the compounds could be tested. "Despite convincing data from laboratory cell cultures, we knew little about how PEITC and curcumin would perform in live animals, especially on prostate cancer," Kong said. "So we undertook this study t...

Botox could help target resistant tumors for treatment

...d increased efforts to develop more drugs to which tumors don't show resistance. To increase the efficacy of...d is a determining factor in the poor prognosis of tumors to cytotoxic treatments," said Gallez. "Botulinum toxin could lead to inhibition of contractions of ...

New cellular flaw found in some virulent breast cancers

...ki said, it may be possible to test women's breast tumors for the presence of the overactive kinase, and the... next five years a movement away from treating all tumors with the same drugs, and instead match specific drugs to tumors based on their molecular characteris...

NJIT engineer poised to take stem cell research a step forward

...tation could help cancer patients who've had large tumors removed from bone, Arinzeh says. In many such surgeries, patients lose their limbs. But if her method of implanting stem cells is shown to induce bone repair, amputation may not be necessary. Stem cells could also help patients suffering from osteopo...

New hybrid virus provides targeted molecular imaging of cancer

...s ability to find, highlight, and deliver genes to tumors in mice. Researchers say the advance, reported in...ng mice, we show that this hybrid virus can target tumors systemically to deliver an imaging or therapeutic gene," says the co-leader of the study, Renata Pas...

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